#SampleID	BarcodeSequence	LinkerPrimerSequence	TARGET_SUBFRAGMENT	ASSIGNED_FROM_GEO	EXPERIMENT_CENTER	TITLE	RUN_PREFIX	AGE	MESALAMINE	BIRTHDATE	HOST_COMMON_NAME	DEPTH	HOST_TAXID	ILLUMINA_TECHNOLOGY	COMMON_NAME	SEX	GASTRIC_INVOLVEMENT	DISEASE_DURATION	BODY_SITE	PERIANAL	ELEVATION	RUN_DATE	TYPE_SAMPLE	COLLECTION_DATE	ALTITUDE	STEROIDS	ENV_BIOME	INFLAMMATIONSTATUS	PLATFORM	ANTIBIOTICS	RACE	STUDY_CENTER	COUNTRY	SMOKING	COLLECTION	HOST_SUBJECT_ID	ANONYMIZED_NAME	TAXON_ID	SAMPLE_CENTER	SAMP_SIZE	DISEASE_EXTENT	AGE_UNIT	STUDY_ID	DISEASESUBTYPE	EXPERIMENT_DESIGN_DESCRIPTION	BIOLOGICS	DIAGNOSIS	BODY_HABITAT	SEQUENCING_METH	B_CAT	IMMUNOSUP	LONGITUDE	ENV_MATTER	TARGET_GENE	DISEASE_STAT	ENV_FEATURE	KEY_SEQ	BIOPSY_LOCATION	BODY_PRODUCT	ILEAL_INVOVLEMENT	REGION	RUN_CENTER	PCR_PRIMERS	LIBRARY_CONSTRUCTION_PROTOCOL	GASTROINTEST_DISORD	LATITUDE	EXTERNAL_ID	Description_duplicate	Description
SKBTI.1325.1246591	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161197	9.083333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	9/2/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0741	SKBTI.1325	408170	BI	.1,g	L3	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.1325	M1-0741 biopsy	CCFA_RISK
121283.1246600	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136332	22.0	None	9/26/89	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:feces	no	15.34	None	stool	8/14/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8603	121283	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121283	8603 stool	CCFA_RISK
SKBTI.0870.1246169	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146974	15.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	12/21/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0606	SKBTI.0870	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0870	M1-0606 biopsy	CCFA_RISK
SKBTI.1178.1246304	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162352	12.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	1/28/11	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0453	SKBTI.1178	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1178	M1-0453 biopsy	CCFA_RISK
MGH101468.1246593	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125757	49.0	yes	4/20/58	human	0	9606	MiSeq	human gut metagenome	male	no	34	UBERON:colon	no	15.34	None	biopsy	11/6/07	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7072	MGH101468	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	yes	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Transverse colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH101468	7072 biopsy	CCFA_RISK
SKBTI047.1246817	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106918	14.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	1/25/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0069	SKBTI047	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI047	M1-0069 biopsy	CCFA_RISK
SKBTI.0972.1247111	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161115	11.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	11/4/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0026	SKBTI.0972	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0972	M1-0026 biopsy	CCFA_RISK
SKBTI.0635.1247107	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133770	11.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/29/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0417	SKBTI.0635	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0635	M1-0417 biopsy	CCFA_RISK
122113.1246583	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153060	30.0	None	10/13/82	human	0	9606	MiSeq	human gut metagenome	female	no	11	UBERON:feces	no	15.34	None	stool	3/1/13	0.0	None	ENVO:urban biome	None	Illumina	None	other	BI	GAZ:United States of America	Never	PRISM	1939:8726	122113	408170	BI	.1,g	J-Pouch	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B2	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122113	8726 stool	CCFA_RISK
SKBTI.1217.1247088	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161102	13.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	12/13/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0768	SKBTI.1217	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1217	M1-0768 biopsy	CCFA_RISK
SKBTI.0945.1246328	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147049	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	4/5/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0539	SKBTI.0945	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0945	M1-0539 biopsy	CCFA_RISK
SKBTI022.1247417	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106893	5.333333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	10/29/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0089	SKBTI022	408170	BI	.1,g	L2	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI022	M1-0089 biopsy	CCFA_RISK
SKBTI.0882.1246581	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146986	8.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	3/7/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0685	SKBTI.0882	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0882	M1-0685 biopsy	CCFA_RISK
MGH100748.1246798	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125794	32.0	no	9/1/74	human	0	9606	MiSeq	human gut metagenome	female	no	2	UBERON:colon	no	15.34	None	biopsy	8/22/07	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7200	MGH100748	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH100748	7200 biopsy	CCFA_RISK
MGH101614.1246411	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125767	40.0	yes	10/5/67	human	0	9606	MiSeq	human gut metagenome	male	no	13	UBERON:colon	no	15.34	None	biopsy	11/28/07	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Current	PRISM	1939:7102	MGH101614	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH101614	7102 biopsy	CCFA_RISK
SKBTI.0285.1246960	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123139	15.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	1/24/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0573	SKBTI.0285	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0285	M1-0573 biopsy	CCFA_RISK
SKBTI.0269.1246526	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123124	10.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	4/4/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0402	SKBTI.0269	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0269	M1-0402 biopsy	CCFA_RISK
SKBTI.0917.1246240	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147021	16.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	7/25/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0705	SKBTI.0917	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0917	M1-0705 biopsy	CCFA_RISK
MGH103785.1247459	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125876	35.0	yes	2/16/73	human	0	9606	MiSeq	human gut metagenome	female	no	7	UBERON:ileum	no	15.34	None	biopsy	6/24/08	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7094	MGH103785	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B3	yes	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH103785	7094 biopsy	CCFA_RISK
121977.1246232	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153029	41.0	None	5/1/71	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:feces	no	15.34	None	stool	1/1/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8636	121977	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121977	8636 stool	CCFA_RISK
SKBTI.1270.1246946	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162452	15.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/29/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0125	SKBTI.1270	408170	BI	.1,g	L3	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1270	M1-0125 biopsy	CCFA_RISK
122007.1247027	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153019	60.0	None	11/5/51	human	0	9606	MiSeq	human gut metagenome	male	no	9	UBERON:feces	no	15.34	None	stool	10/25/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8592	122007	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122007	8592 stool	CCFA_RISK
121502.1246527	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136422	39.0	None	4/10/71	human	0	9606	MiSeq	human gut metagenome	male	no	19	UBERON:feces	yes	15.34	None	stool	3/17/11	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8226	121502	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121502	8226 stool	CCFA_RISK
SKBTI087.1246525	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106958	13.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	yes	15.34	None	biopsy	8/24/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0523	SKBTI087	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI087	M1-0523 biopsy	CCFA_RISK
SKBTI.0171.1246915	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123021	7.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/14/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0361	SKBTI.0171	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0171	M1-0361 biopsy	CCFA_RISK
SKBTI059.1247180	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106930	15.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	11/3/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0263	SKBTI059	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI059	M1-0263 biopsy	CCFA_RISK
SKBTI.0220.1246190	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123076	13.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	2/26/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0071	SKBTI.0220	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0220	M1-0071 biopsy	CCFA_RISK
SKBTI014.1246923	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106885	10.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	2/4/09	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0203	SKBTI014	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI014	M1-0203 biopsy	CCFA_RISK
SKBTI.0100.1246820	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122955	10.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	1/14/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0009	SKBTI.0100	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0100	M1-0009 biopsy	CCFA_RISK
SKBTI.1191.1247392	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162360	4.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	1/23/12	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0411	SKBTI.1191	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1191	M1-0411 biopsy	CCFA_RISK
SKBTI050.1246700	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106921	8.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	11/17/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0599	SKBTI050	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI050	M1-0599 biopsy	CCFA_RISK
SKBTI.0512.1246797	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133647	15.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	5/12/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0541	SKBTI.0512	408170	BI	.1,g	L2	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0512	M1-0541 biopsy	CCFA_RISK
100217.1246514	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127137	20.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100217	100217	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	yes	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100217	OR100217 stool	CCFA_RISK
SKBTI.0513.1246597	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133648	12.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/2/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0693	SKBTI.0513	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0513	M1-0693 biopsy	CCFA_RISK
SKBTI.0577.1246680	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133712	14.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	6/16/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0135	SKBTI.0577	408170	BI	.1,g	L3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0577	M1-0135 biopsy	CCFA_RISK
100115.1246245	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125861	15.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100115	100115	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100115	OR100115 stool	CCFA_RISK
100087.1246709	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125844	8.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100087	100087	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100087	OR100087 stool	CCFA_RISK
SKBTI.0732.1246896	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155049	13.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	11/8/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0645	SKBTI.0732	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0732	M1-0645 biopsy	CCFA_RISK
SKBTI.0195.1246195	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123053	10.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	8/2/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0251	SKBTI.0195	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0195	M1-0251 biopsy	CCFA_RISK
SKBTI.0112.1246824	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122967	14.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/29/10	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0491	SKBTI.0112	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0112	M1-0491 biopsy	CCFA_RISK
SKBTI.1251.1247304	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162441	4.166666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	3/29/12	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0806	SKBTI.1251	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1251	M1-0806 biopsy	CCFA_RISK
121492.1246983	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136413	35.0	None	6/13/76	human	0	9606	MiSeq	human gut metagenome	female	no	22	UBERON:feces	no	15.34	None	stool	1/30/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8440	121492	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121492	8440 stool	CCFA_RISK
SKBTI.1272.1246551	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162454	13.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	5/2/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0695	SKBTI.1272	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1272	M1-0695 biopsy	CCFA_RISK
SKBTI.0908.1247330	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147012	7.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	2/8/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0611	SKBTI.0908	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0908	M1-0611 biopsy	CCFA_RISK
SKBTI.0966.1246408	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161113	14.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:cecum	no	15.34	None	biopsy	2/25/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0813	SKBTI.0966	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0966	M1-0813 biopsy	CCFA_RISK
SKBTI006.1247355	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106877	11.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	2/20/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0012	SKBTI006	408170	BI	.1,g	L3	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI006	M1-0012 biopsy	CCFA_RISK
SKBTI.0564.1246636	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133699	16.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/6/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0699	SKBTI.0564	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0564	M1-0699 biopsy	CCFA_RISK
SKBTI.0140.1246133	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122992	11.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	8/5/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0253	SKBTI.0140	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0140	M1-0253 biopsy	CCFA_RISK
SKBTI.0545.1247474	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133680	13.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	5/25/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0374	SKBTI.0545	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0545	M1-0374 biopsy	CCFA_RISK
SKBTI.0498.1246374	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133709	16.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	4/20/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0460	SKBTI.0498	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0498	M1-0460 biopsy	CCFA_RISK
MGH112053.1246811	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125737	56.0	yes	10/7/53	human	0	9606	MiSeq	human gut metagenome	female	no	31	UBERON:colon	no	15.34	None	biopsy	11/17/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7775	MGH112053	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH112053	7775 biopsy	CCFA_RISK
SKBTI.0172.1246267	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123022	12.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	5/18/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	arab	BI	GAZ:United States of America	None	RISK	1939:M1-0239	SKBTI.0172	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0172	M1-0239 biopsy	CCFA_RISK
SKBTI.0634.1246139	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133769	15.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	None	15.34	None	biopsy	5/17/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0385	SKBTI.0634	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0634	M1-0385 biopsy	CCFA_RISK
SKBTI079.1247266	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106950	14.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/5/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0074	SKBTI079	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI079	M1-0074 biopsy	CCFA_RISK
SKBTI.0761.1246264	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155060	12.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	11/29/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0097	SKBTI.0761	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0761	M1-0097 biopsy	CCFA_RISK
MGH104519.1246177	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125886	44.0	yes	6/11/64	human	0	9606	MiSeq	human gut metagenome	female	no	13	UBERON:colon	yes	15.34	None	biopsy	8/27/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7325	MGH104519	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH104519	7325 biopsy	CCFA_RISK
SKBTI.1177.1246155	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161089	15.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	6/23/10	0.0	no	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	None	RISK	1939:M1-0447	SKBTI.1177	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1177	M1-0447 biopsy	CCFA_RISK
SKBTI.0744.1247422	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135658	7.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	1/24/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0397	SKBTI.0744	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0744	M1-0397 biopsy	CCFA_RISK
100074.1247405	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125835	54.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	2	OSCCAR	1939:OR100074	100074	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100074	OR100074 stool	CCFA_RISK
SKBTI.0221.1247435	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123077	15.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/2/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0383	SKBTI.0221	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0221	M1-0383 biopsy	CCFA_RISK
121311.1246878	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136339	21.0	None	5/9/91	human	0	9606	MiSeq	human gut metagenome	male	no	5	UBERON:feces	yes	15.34	None	stool	7/6/12	0.0	None	ENVO:urban biome	None	Illumina	None	other	BI	GAZ:United States of America	Never	PRISM	1939:8562	121311	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121311	8562 stool	CCFA_RISK
SKBTI.0493.1246747	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133628	12.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/4/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0689	SKBTI.0493	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0493	M1-0689 biopsy	CCFA_RISK
SKBTI.0722.1247245	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135640	8.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	10/27/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0290	SKBTI.0722	408170	BI	.1,g	L3	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0722	M1-0290 biopsy	CCFA_RISK
SKBTI.0655.1246662	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133790	9.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/25/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0704	SKBTI.0655	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0655	M1-0704 biopsy	CCFA_RISK
SKBTI.0578.1247315	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133703	9.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/16/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0330	SKBTI.0578	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0578	M1-0330 biopsy	CCFA_RISK
121971.1246158	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153027	77.0	None	7/7/35	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:feces	yes	15.34	None	stool	11/6/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8629	121971	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121971	8629 stool	CCFA_RISK
SKBTI.1246.1247160	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162393	10.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	4/4/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0402	SKBTI.1246	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1246	M1-0402 biopsy	CCFA_RISK
SKBTI.0530.1246967	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133665	11.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	5/19/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0325	SKBTI.0530	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0530	M1-0325 biopsy	CCFA_RISK
SKBTI.0500.1247476	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155024	12.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/21/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0582	SKBTI.0500	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0500	M1-0582 biopsy	CCFA_RISK
SKBTI.1265.1246692	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162447	15.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/27/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0601	SKBTI.1265	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1265	M1-0601 biopsy	CCFA_RISK
SKBTI.1007.1246208	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161131	12.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	3/25/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0304	SKBTI.1007	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1007	M1-0304 biopsy	CCFA_RISK
100192.1247106	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127119	47.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	2	OSCCAR	1939:OR100192	100192	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100192	OR100192 stool	CCFA_RISK
SKBTI.0739.1246718	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155051	5.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	1/24/12	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0604	SKBTI.0739	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0739	M1-0604 biopsy	CCFA_RISK
122116.1246222	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153069	21.0	None	8/2/91	human	0	9606	MiSeq	human gut metagenome	female	yes	1	UBERON:feces	yes	15.34	None	stool	3/4/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8649	122116	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122116	8649 stool	CCFA_RISK
121191.1246140	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136308	24.0	None	6/13/87	human	0	9606	MiSeq	human gut metagenome	male	no	9	UBERON:feces	no	15.34	None	stool	3/19/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Current	PRISM	1939:8478	121191	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121191	8478 stool	CCFA_RISK
SKBTI.0215.1246555	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123071	8.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	2/22/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0225	SKBTI.0215	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0215	M1-0225 biopsy	CCFA_RISK
100065.1246135	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125830	20.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100065	100065	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100065	OR100065 stool	CCFA_RISK
SKBTI.0610.1246310	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133745	15.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/4/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0703	SKBTI.0610	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0610	M1-0703 biopsy	CCFA_RISK
121314.1247259	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136342	19.0	None	12/27/92	human	0	9606	MiSeq	human gut metagenome	female	no	10	UBERON:feces	yes	15.34	None	stool	9/11/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8618	121314	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121314	8618 stool	CCFA_RISK
SKBTI092.1247177	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106963	7.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/29/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0300	SKBTI092	408170	BI	.1,g	L1	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI092	M1-0300 biopsy	CCFA_RISK
SKBTI.1283.1247418	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161180	7.333333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	8/25/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0288	SKBTI.1283	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1283	M1-0288 biopsy	CCFA_RISK
121501.1246321	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136421	39.0	None	9/10/73	human	0	9606	MiSeq	human gut metagenome	male	no	9	UBERON:feces	no	15.34	None	stool	10/23/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Current	PRISM	1939:8639	121501	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121501	8639 stool	CCFA_RISK
SKBTI.1252.1247124	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162442	4.166666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/29/12	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0806	SKBTI.1252	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1252	M1-0806 biopsy	CCFA_RISK
SKBTI.1106.1246873	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162325	12.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	7/25/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0842	SKBTI.1106	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1106	M1-0842 biopsy	CCFA_RISK
121444.1246866	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136361	29.0	None	1/21/83	human	0	9606	MiSeq	human gut metagenome	female	no	12	UBERON:feces	no	15.34	None	stool	9/19/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Current	PRISM	1939:8624	121444	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121444	8624 stool	CCFA_RISK
SKBTI.0633.1246227	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133768	13.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	5/12/10	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0362	SKBTI.0633	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0633	M1-0362 biopsy	CCFA_RISK
100083.1246311	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125841	37.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100083	100083	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100083	OR100083 stool	CCFA_RISK
SKBTI.0256.1246764	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123111	9.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	None	15.34	None	biopsy	3/15/11	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0578	SKBTI.0256	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0256	M1-0578 biopsy	CCFA_RISK
SKBTI.0202.1246326	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123059	16.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	12/24/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0222	SKBTI.0202	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0202	M1-0222 biopsy	CCFA_RISK
SKBTI.0626.1246860	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133761	13.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	7/15/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0284	SKBTI.0626	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0626	M1-0284 biopsy	CCFA_RISK
SKBTI.1339.1247442	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161205	16.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	10/13/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0730	SKBTI.1339	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1339	M1-0730 biopsy	CCFA_RISK
SKBTI.0562.1247438	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133697	4.333333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	6/13/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0667	SKBTI.0562	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0562	M1-0667 biopsy	CCFA_RISK
SKBTI.1087.1247320	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162314	12.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	12/6/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0393	SKBTI.1087	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1087	M1-0393 biopsy	CCFA_RISK
MGH109682.1247344	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125729	60.0	no	5/27/49	human	0	9606	MiSeq	human gut metagenome	female	no	29	UBERON:colon	no	15.34	None	biopsy	9/1/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7614	MGH109682	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Ascending colon	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH109682	7614 biopsy	CCFA_RISK
100203.1246754	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127126	29.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	2	OSCCAR	1939:OR100203	100203	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100203	OR100203 stool	CCFA_RISK
SKBTI.0895.1246868	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146999	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	5/31/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0129	SKBTI.0895	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0895	M1-0129 biopsy	CCFA_RISK
SKBTI.0944.1246472	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147048	15.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	4/1/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0538	SKBTI.0944	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0944	M1-0538 biopsy	CCFA_RISK
SKBTI.0607.1246446	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133742	14.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/30/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0465	SKBTI.0607	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0607	M1-0465 biopsy	CCFA_RISK
SKBTI.0174.1247076	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123024	14.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	yes	15.34	None	biopsy	5/21/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0240	SKBTI.0174	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0174	M1-0240 biopsy	CCFA_RISK
SKBTI.0727.1246209	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135645	15.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	10/7/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0616	SKBTI.0727	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0727	M1-0616 biopsy	CCFA_RISK
SKBTI.0927.1247468	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147031	9.416666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	5/16/12	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0711	SKBTI.0927	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0927	M1-0711 biopsy	CCFA_RISK
SKBTI.1205.1247372	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162371	10.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	2/14/12	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0056	SKBTI.1205	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1205	M1-0056 biopsy	CCFA_RISK
SKBTI.0532.1247122	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133667	10.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/25/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0542	SKBTI.0532	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0532	M1-0542 biopsy	CCFA_RISK
SKBTI.0520.1246392	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133655	15.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/11/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0662	SKBTI.0520	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0520	M1-0662 biopsy	CCFA_RISK
SKBTI.0689.1246344	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135701	11.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	yes	15.34	None	biopsy	8/16/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0256	SKBTI.0689	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0689	M1-0256 biopsy	CCFA_RISK
100195.1247038	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127120	65.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	2	OSCCAR	1939:OR100195	100195	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100195	OR100195 stool	CCFA_RISK
122061.1247260	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153051	22.0	None	2/14/91	human	0	9606	MiSeq	human gut metagenome	male	no	1	UBERON:feces	no	15.34	None	stool	2/25/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Current	PRISM	1939:8678	122061	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	122061	8678 stool	CCFA_RISK
SKBTI.1351.1246314	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161021	6.166666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	10/26/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0473	SKBTI.1351	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1351	M1-0473 biopsy	CCFA_RISK
SKBTI.1016.1246272	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161138	9.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:cecum	no	15.34	None	biopsy	5/17/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0075	SKBTI.1016	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1016	M1-0075 biopsy	CCFA_RISK
100227.1246626	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127145	51.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100227	100227	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100227	OR100227 stool	CCFA_RISK
SKBTI.0107.1247323	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135933	10.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/15/09	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0201	SKBTI.0107	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0107	M1-0201 biopsy	CCFA_RISK
100068.1246376	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125831	33.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100068	100068	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	100068	OR100068 stool	CCFA_RISK
SKBTI.1332.1246892	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161200	11.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	10/12/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0729	SKBTI.1332	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1332	M1-0729 biopsy	CCFA_RISK
121186.1246365	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136303	68.0	None	4/3/43	human	0	9606	MiSeq	human gut metagenome	male	no	50	UBERON:feces	no	15.34	None	stool	3/28/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8444	121186	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121186	8444 stool	CCFA_RISK
121461.1247420	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136285	62.0	None	11/20/47	human	0	9606	MiSeq	human gut metagenome	male	yes	12	UBERON:feces	no	15.34	None	stool	1/19/10	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:7839	121461	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121461	7839 stool	CCFA_RISK
SKBTI.1355.1246399	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162303	14.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	None	15.34	None	biopsy	10/27/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0784	SKBTI.1355	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1355	M1-0784 biopsy	CCFA_RISK
SKBTI.1050.1246293	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161164	13.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	9/22/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0827	SKBTI.1050	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1050	M1-0827 biopsy	CCFA_RISK
SKBTI.0362.1246358	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29E7.1.Solexa-124725	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	12/20/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0104	SKBTI.0362	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0362	M1-0104 biopsy	CCFA_RISK
SKBTI.0663.1247277	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133798	10.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	None	15.34	None	biopsy	8/1/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0673	SKBTI.0663	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0663	M1-0673 biopsy	CCFA_RISK
SKBTI.0169.1247246	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123019	14.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	4/12/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0073	SKBTI.0169	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0169	M1-0073 biopsy	CCFA_RISK
SKBTI.0164.1247217	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123014	13.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	5/12/10	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0362	SKBTI.0164	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0164	M1-0362 biopsy	CCFA_RISK
100046.1246388	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125821	61.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100046	100046	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100046	OR100046 stool	CCFA_RISK
SKBTI.0179.1246791	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123028	15.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/6/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0241	SKBTI.0179	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0179	M1-0241 biopsy	CCFA_RISK
122057.1246885	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153039	21.0	None	8/2/91	human	0	9606	MiSeq	human gut metagenome	female	yes	1	UBERON:feces	yes	15.34	None	stool	1/2/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8649	122057	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122057	8649 stool	CCFA_RISK
SKBTI.0660.1246329	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133795	16.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	7/29/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0467	SKBTI.0660	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0660	M1-0467 biopsy	CCFA_RISK
100086.1247268	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125843	80.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100086	100086	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100086	OR100086 stool	CCFA_RISK
SKBTI.0936.1247276	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147040	15.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	yes	15.34	None	biopsy	5/17/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0420	SKBTI.0936	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0936	M1-0420 biopsy	CCFA_RISK
MGH103446.1246319	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125751	54.0	yes	12/14/53	human	0	9606	MiSeq	human gut metagenome	male	no	18	UBERON:rectum	no	15.34	None	biopsy	5/13/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7043	MGH103446	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	UC	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH103446	biopsy 7043	CCFA_RISK
SKBTI.1186.1247395	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162358	15.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	3/1/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0315	SKBTI.1186	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1186	M1-0315 biopsy	CCFA_RISK
SKBTI057.1246676	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106928	16.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	2/12/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0293	SKBTI057	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI057	M1-0293 biopsy	CCFA_RISK
SKBTI.0561.1246516	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133696	15.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	None	15.34	None	biopsy	6/9/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0666	SKBTI.0561	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0561	M1-0666 biopsy	CCFA_RISK
SKBTI.1039.1246497	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161155	10.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	8/26/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0819	SKBTI.1039	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1039	M1-0819 biopsy	CCFA_RISK
SKBTI.0629.1246291	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133764	11.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/25/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0466	SKBTI.0629	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0629	M1-0466 biopsy	CCFA_RISK
SKBTI.1348.1247427	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162300	8.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	10/21/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0835	SKBTI.1348	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1348	M1-0835 biopsy	CCFA_RISK
MGH113669.1247130	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136039	27.0	no	3/3/82	human	0	9606	MiSeq	human gut metagenome	female	None	9	UBERON:colon	None	15.34	None	biopsy	2/3/10	0.0	yes	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7871	MGH113669	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	MGH113669	7871 biopsy	CCFA_RISK
SKBTI.1305.1246664	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162469	10.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	5/2/12	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0740	SKBTI.1305	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1305	M1-0740 biopsy	CCFA_RISK
SKBTI.0697.1247296	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155064	9.416666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	11/9/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0528	SKBTI.0697	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0697	M1-0528 biopsy	CCFA_RISK
SKBTI090.1246347	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106961	12.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	4/29/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0188	SKBTI090	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI090	M1-0188 biopsy	CCFA_RISK
SKBTI.0933.1246235	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147037	10.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	4/14/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0550	SKBTI.0933	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0933	M1-0550 biopsy	CCFA_RISK
SKBTI.1193.1246398	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162362	4.666666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/27/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0734	SKBTI.1193	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1193	M1-0734 biopsy	CCFA_RISK
MGH103547.1247433	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125761	55.0	yes	12/10/52	human	0	9606	MiSeq	human gut metagenome	male	no	35	UBERON:colon	yes	15.34	None	biopsy	6/10/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7085	MGH103547	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	yes	CD	UBERON:gastrointestinal system	sequencing by synthesis	B3	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH103547	7085 biopsy	CCFA_RISK
SKBTI.1160.1246345	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161080	9.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	yes	15.34	None	biopsy	7/26/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0822	SKBTI.1160	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1160	M1-0822 biopsy	CCFA_RISK
SKBTI.0981.1247206	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162408	8.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:cecum	no	15.34	None	biopsy	2/22/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0225	SKBTI.0981	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0981	M1-0225 biopsy	CCFA_RISK
SKBTI.0209.1247020	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123065	13.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	1/29/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0070	SKBTI.0209	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0209	M1-0070 biopsy	CCFA_RISK
MGH104119.1246223	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125754	40.0	no	6/23/68	human	0	9606	MiSeq	human gut metagenome	female	no	12	UBERON:ileum	yes	15.34	None	biopsy	7/15/08	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7059	MGH104119	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	yes	CD	UBERON:gastrointestinal system	sequencing by synthesis	B3	yes	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH104119	7059 biopsy	CCFA_RISK
SKBTI.1148.1246752	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162437	6.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:colon	no	15.34	None	biopsy	8/16/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0469	SKBTI.1148	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Ascending colon	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1148	M1-0469 biopsy	CCFA_RISK
SKBTI.0679.1247172	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135691	8.666666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/1/12	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0154	SKBTI.0679	408170	BI	.1,g	L3	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0679	M1-0154 biopsy	CCFA_RISK
SKBTI.0130.1246625	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122982	12.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	10/27/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0218	SKBTI.0130	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0130	M1-0218 biopsy	CCFA_RISK
SKBTI.1113.1246880	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161054	13.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:colon	no	15.34	None	biopsy	7/25/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0781	SKBTI.1113	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Ascending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1113	M1-0781 biopsy	CCFA_RISK
SKBTI.0597.1246309	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133732	16.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/31/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0688	SKBTI.0597	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0597	M1-0688 biopsy	CCFA_RISK
122116.1246717	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153044	21.0	None	8/2/91	human	0	9606	MiSeq	human gut metagenome	female	yes	1	UBERON:feces	yes	15.34	None	stool	3/4/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8649	122116	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122116	8649 stool	CCFA_RISK
SKBTI.0550.1246570	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133685	12.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	None	15.34	None	biopsy	5/25/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0664	SKBTI.0550	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0550	M1-0664 biopsy	CCFA_RISK
SKBTI.0188.1246738	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123036	12.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	7/22/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0423	SKBTI.0188	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0188	M1-0423 biopsy	CCFA_RISK
SKBTI.1207.1246567	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161095	3.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	2/8/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0108	SKBTI.1207	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1207	M1-0108 biopsy	CCFA_RISK
121954.1247408	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153058	31.0	None	12/4/81	human	0	9606	MiSeq	human gut metagenome	male	no	6	UBERON:feces	no	15.34	None	stool	1/23/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8700	121954	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121954	8700 stool	CCFA_RISK
SKBTI044.1246151	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106915	10.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	1/20/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0068	SKBTI044	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI044	M1-0068 biopsy	CCFA_RISK
SKBTI.0154.1246746	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-154976	9.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	7/30/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	east_asian	BI	GAZ:United States of America	None	RISK	1939:M1-0497	SKBTI.0154	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0154	M1-0497 biopsy	CCFA_RISK
100160.1246616	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125865	48.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100160	100160	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100160	OR100160 stool	CCFA_RISK
SKBTI.0213.1246213	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-154999	13.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	2/9/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0302	SKBTI.0213	408170	BI	.1,g	L2	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0213	M1-0302 biopsy	CCFA_RISK
SKBTI.0255.1247176	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136013	13.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/15/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0111	SKBTI.0255	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0255	M1-0111 biopsy	CCFA_RISK
SKBTI.1073.1246935	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161039	15.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	None	15.34	None	biopsy	10/25/10	0.0	no	ENVO:urban biome	None	Illumina	no	east_asian	BI	GAZ:United States of America	None	RISK	1939:M1-0392	SKBTI.1073	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1073	M1-0392 biopsy	CCFA_RISK
SKBTI.0137.1246515	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122989	15.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	8/2/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0252	SKBTI.0137	408170	BI	.1,g	L1	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0137	M1-0252 biopsy	CCFA_RISK
100178.1246691	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127109	51.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100178	100178	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100178	OR100178 stool	CCFA_RISK
121194.1246890	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136311	68.0	None	1/12/44	human	0	9606	MiSeq	human gut metagenome	male	no	8	UBERON:feces	no	15.34	None	stool	5/15/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:7184	121194	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121194	7184 stool	CCFA_RISK
SKBTI.0559.1246999	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133694	14.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	yes	15.34	None	biopsy	6/10/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0560	SKBTI.0559	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0559	M1-0560 biopsy	CCFA_RISK
SKBTI.0581.1247204	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133716	14.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/23/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0331	SKBTI.0581	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0581	M1-0331 biopsy	CCFA_RISK
100216.1246217	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127136	60.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100216	100216	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100216	OR100216 stool	CCFA_RISK
SKBTI060.1247467	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106931	11.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/3/09	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0018	SKBTI060	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI060	M1-0018 biopsy	CCFA_RISK
MGH102278.1246387	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125786	30.0	no	7/23/77	human	0	9606	MiSeq	human gut metagenome	male	no	17	UBERON:colon	no	15.34	None	biopsy	2/26/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7168	MGH102278	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	yes	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH102278	7168 biopsy	CCFA_RISK
MGH102228.1246744	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125885	42.0	no	7/10/65	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:colon	None	15.34	None	biopsy	2/25/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7313	MGH102228	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Recto-Sigmoid	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	MGH102228	7313 biopsy	CCFA_RISK
121313.1246613	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136341	31.0	None	1/22/81	human	0	9606	MiSeq	human gut metagenome	female	no	3	UBERON:feces	no	15.34	None	stool	7/20/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8573	121313	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121313	8573 stool	CCFA_RISK
SKBTI.0264.1247471	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123119	11.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/12/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0679	SKBTI.0264	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0264	M1-0679 biopsy	CCFA_RISK
SKBTI.0485.1246351	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133620	15.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	None	15.34	None	biopsy	4/7/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0628	SKBTI.0485	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0485	M1-0628 biopsy	CCFA_RISK
SKBTI.0551.1246805	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133686	15.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	yes	15.34	None	biopsy	5/24/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0696	SKBTI.0551	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0551	M1-0696 biopsy	CCFA_RISK
122076.1247261	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153008	30.0	None	10/8/82	human	0	9606	MiSeq	human gut metagenome	female	no	1	UBERON:feces	no	15.34	None	stool	3/5/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8582	122076	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122076	8582 stool	CCFA_RISK
SKBTI076.1246468	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127161	9.416666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/1/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0166	SKBTI076	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI076	M1-0166 biopsy	CCFA_RISK
SKBTI.1343.1246914	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162487	16.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	10/18/11	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0791	SKBTI.1343	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1343	M1-0791 biopsy	CCFA_RISK
SKBTI.0692.1246233	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135612	13.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	9/30/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0337	SKBTI.0692	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0692	M1-0337 biopsy	CCFA_RISK
122164.1246663	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153047	29.0	None	7/1/83	human	0	9606	MiSeq	human gut metagenome	female	no	3	UBERON:feces	no	15.34	None	stool	12/6/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8670	122164	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	122164	8670 stool	CCFA_RISK
100095.1246168	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125850	41.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100095	100095	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	yes	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100095	OR100095 stool	CCFA_RISK
121188.1247234	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136305	30.0	None	9/20/81	human	0	9606	MiSeq	human gut metagenome	male	None	7	UBERON:feces	None	15.34	None	stool	3/1/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8457	121188	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	121188	8457 stool	CCFA_RISK
100106.1246858	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125858	26.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100106	100106	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100106	OR100106 stool	CCFA_RISK
SKBTI075.1247167	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106946	10.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	8/5/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0349	SKBTI075	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI075	M1-0349 biopsy	CCFA_RISK
SKBTI.0103.1246121	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122958	9.666666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/23/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0210	SKBTI.0103	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0103	M1-0210 biopsy	CCFA_RISK
SKBTI.0165.1247112	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123015	15.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	5/13/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0238	SKBTI.0165	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0165	M1-0238 biopsy	CCFA_RISK
SKBTI.1194.1246932	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162363	4.666666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	1/27/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0734	SKBTI.1194	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1194	M1-0734 biopsy	CCFA_RISK
SKBTI.0750.1247414	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155056	14.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	6/16/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0243	SKBTI.0750	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0750	M1-0243 biopsy	CCFA_RISK
100222.1247291	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127141	33.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100222	100222	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100222	OR100222 stool	CCFA_RISK
122100.1246447	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153070	21.0	None	8/2/91	human	0	9606	MiSeq	human gut metagenome	female	yes	1	UBERON:feces	yes	15.34	None	stool	3/4/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8649	122100	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122100	8649 stool	CCFA_RISK
SKBTI.1025.1247303	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161144	16.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	7/29/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0787	SKBTI.1025	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1025	M1-0787 biopsy	CCFA_RISK
SKBTI.0598.1247404	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133733	16.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/29/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0694	SKBTI.0598	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0598	M1-0694 biopsy	CCFA_RISK
SKBTI.1047.1247373	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161162	16.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	9/17/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0833	SKBTI.1047	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1047	M1-0833 biopsy	CCFA_RISK
SKBTI.0129.1246157	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122981	9.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	yes	15.34	None	biopsy	10/7/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0217	SKBTI.0129	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0129	M1-0217 biopsy	CCFA_RISK
122115.1247226	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153063	30.0	None	10/13/82	human	0	9606	MiSeq	human gut metagenome	female	no	11	UBERON:feces	no	15.34	None	stool	3/1/13	0.0	None	ENVO:urban biome	None	Illumina	None	other	BI	GAZ:United States of America	Never	PRISM	1939:8726	122115	408170	BI	.1,g	J-Pouch	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B2	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122115	8726 stool	CCFA_RISK
SKBTI.1124.1246490	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161061	12.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	7/29/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0743	SKBTI.1124	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1124	M1-0743 biopsy	CCFA_RISK
121981.1247080	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153025	23.0	None	1/17/90	human	0	9606	MiSeq	human gut metagenome	male	no	1	UBERON:feces	no	15.34	None	stool	2/12/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8600	121981	408170	BI	.1,g	E3	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	121981	8600 stool	CCFA_RISK
SKBTI.0670.1246349	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133785	6.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	8/26/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0482	SKBTI.0670	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0670	M1-0482 biopsy	CCFA_RISK
SKBTI.0599.1246538	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133734	16.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	6/9/11	0.0	no	ENVO:urban biome	None	Illumina	no	arab	BI	GAZ:United States of America	None	RISK	1939:M1-0700	SKBTI.0599	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0599	M1-0700 biopsy	CCFA_RISK
MGH101725.1247251	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125753	57.0	yes	8/21/50	human	0	9606	MiSeq	human gut metagenome	male	yes	6	UBERON:colon	no	15.34	None	biopsy	12/18/07	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7052	MGH101725	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Transverse colon	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH101725	7052 biopsy	CCFA_RISK
SKBTI.0996.1246375	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161124	14.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:colon	yes	15.34	None	biopsy	3/31/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0359	SKBTI.0996	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Ascending colon	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0996	M1-0359 biopsy	CCFA_RISK
SKBTI.0241.1246904	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123096	7.666666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	3/7/11	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0400	SKBTI.0241	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0241	M1-0400 biopsy	CCFA_RISK
SKBTI.0170.1246571	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123020	10.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/14/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0550	SKBTI.0170	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0170	M1-0550 biopsy	CCFA_RISK
122098.1247178	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153062	30.0	None	10/13/82	human	0	9606	MiSeq	human gut metagenome	female	no	11	UBERON:feces	no	15.34	None	stool	3/1/13	0.0	None	ENVO:urban biome	None	Illumina	None	other	BI	GAZ:United States of America	Never	PRISM	1939:8726	122098	408170	BI	.1,g	J-Pouch	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B2	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122098	8726 stool	CCFA_RISK
SKBTI.0574.1246493	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133802	11.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	6/13/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0668	SKBTI.0574	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0574	M1-0668 biopsy	CCFA_RISK
SKBTI.0839.1246690	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WCA.1.Solexa-150163	9.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	None	15.34	None	biopsy	3/15/11	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0578	SKBTI.0839	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0839	M1-0578 biopsy	CCFA_RISK
SKBTI.1104.1246588	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162323	10.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	7/22/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0831	SKBTI.1104	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1104	M1-0831 biopsy	CCFA_RISK
SKBTI.1176.1247064	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162351	13.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:cecum	None	15.34	None	biopsy	3/3/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0840	SKBTI.1176	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1176	M1-0840 biopsy	CCFA_RISK
SKBTI.1345.1246175	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161017	11.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	12/20/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0428	SKBTI.1345	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1345	M1-0428 biopsy	CCFA_RISK
MGH113527.1246397	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125730	24.0	no	5/16/85	human	0	9606	MiSeq	human gut metagenome	female	yes	14	UBERON:colon	no	15.34	None	biopsy	1/27/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7615	MGH113527	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	yes	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH113527	7615 biopsy	CCFA_RISK
MGH106399.1247406	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125723	60.0	no	6/7/48	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:colon	None	15.34	None	biopsy	4/15/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7385	MGH106399	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	MGH106399	7385 biopsy	CCFA_RISK
SKBTI.0659.1247328	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133794	14.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	8/5/11	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0406	SKBTI.0659	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0659	M1-0406 biopsy	CCFA_RISK
SKBTI.1091.1247164	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161046	17.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	12/8/10	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0714	SKBTI.1091	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1091	M1-0714 biopsy	CCFA_RISK
SKBTI.0534.1247001	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133669	10.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	None	15.34	None	biopsy	5/13/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0632	SKBTI.0534	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0534	M1-0632 biopsy	CCFA_RISK
SKBTI002.1247215	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106873	11.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	11/4/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0026	SKBTI002	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI002	M1-0026 biopsy	CCFA_RISK
100234.1246324	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127149	7.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100234	100234	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	yes	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100234	OR100234 stool	CCFA_RISK
SKBTI.1301.1247194	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162467	10.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	5/18/12	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0476	SKBTI.1301	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1301	M1-0476 biopsy	CCFA_RISK
SKBTI.0992.1246474	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161122	9.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:colon	no	15.34	None	biopsy	12/23/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0031	SKBTI.0992	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0992	M1-0031 biopsy	CCFA_RISK
MGH106288.1247403	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125775	57.0	yes	2/27/52	human	0	9606	MiSeq	human gut metagenome	male	no	17	UBERON:colon	no	15.34	None	biopsy	4/7/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7129	MGH106288	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH106288	7129 biopsy	CCFA_RISK
SKBTI.0489.1246909	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133624	14.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	3/4/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0590	SKBTI.0489	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0489	M1-0590 biopsy	CCFA_RISK
SKBTI.0117.1247282	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122971	15.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	11/11/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0066	SKBTI.0117	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0117	M1-0066 biopsy	CCFA_RISK
SKBTI.0272.1247188	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123127	15.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	4/1/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0538	SKBTI.0272	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0272	M1-0538 biopsy	CCFA_RISK
MGH103029.1246825	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125745	30.0	no	4/6/78	human	0	9606	MiSeq	human gut metagenome	male	no	3	UBERON:rectum	no	15.34	None	biopsy	4/23/08	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7018	MGH103029	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH103029	7018 biopsy	CCFA_RISK
SKBTI045.1246556	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106916	14.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	11/12/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0067	SKBTI045	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI045	M1-0067 biopsy	CCFA_RISK
SKBTI.0958.1246251	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147062	12.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	12/19/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0618	SKBTI.0958	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0958	M1-0618 biopsy	CCFA_RISK
100226.1246263	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127144	62.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	2	OSCCAR	1939:OR100226	100226	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	yes	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100226	OR100226 stool	CCFA_RISK
SKBTI.0919.1246366	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147023	10.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	3/9/12	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0152	SKBTI.0919	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0919	M1-0152 biopsy	CCFA_RISK
SKBTI.0549.1247310	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133684	13.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	None	15.34	None	biopsy	5/31/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0634	SKBTI.0549	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0549	M1-0634 biopsy	CCFA_RISK
SKBTI.0180.1246773	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123047	12.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/6/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0388	SKBTI.0180	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0180	M1-0388 biopsy	CCFA_RISK
SKBTI.0757.1246505	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135670	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	yes	15.34	None	biopsy	4/18/11	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0692	SKBTI.0757	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0757	M1-0692 biopsy	CCFA_RISK
SKBTI.0623.1246521	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133758	11.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	7/1/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0623	SKBTI.0623	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0623	M1-0623 biopsy	CCFA_RISK
SKBTI.1004.1247345	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161130	None	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:cecum	None	15.34	None	biopsy	3/15/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0357	SKBTI.1004	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1004	M1-0357 biopsy	CCFA_RISK
SKBTI.1138.1247238	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161069	12.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	8/10/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0820	SKBTI.1138	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1138	M1-0820 biopsy	CCFA_RISK
SKBTI.0627.1247444	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133762	11.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/21/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0335	SKBTI.0627	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0627	M1-0335 biopsy	CCFA_RISK
121200.1246461	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136317	34.0	None	1/11/78	human	0	9606	MiSeq	human gut metagenome	female	no	4	UBERON:feces	no	15.34	None	stool	5/30/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8529	121200	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121200	8529 stool	CCFA_RISK
100070.1246721	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125832	12.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100070	100070	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100070	OR100070 stool	CCFA_RISK
122163.1246898	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153049	21.0	None	2/14/91	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:feces	no	15.34	None	stool	12/17/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Current	PRISM	1939:8678	122163	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	122163	8678 stool	CCFA_RISK
SKBTI.1114.1246342	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161055	13.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	7/25/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0781	SKBTI.1114	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1114	M1-0781 biopsy	CCFA_RISK
MGH109531.1246394	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125724	31.0	no	5/19/78	human	0	9606	MiSeq	human gut metagenome	female	no	2	UBERON:ileum	no	15.34	None	biopsy	8/19/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7429	MGH109531	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH109531	7429 biopsy	CCFA_RISK
SKBTI003.1247462	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106874	14.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	12/30/08	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0198	SKBTI003	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI003	M1-0198 biopsy	CCFA_RISK
121980.1247090	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153085	48.0	None	1/8/65	human	0	9606	MiSeq	human gut metagenome	female	no	1	UBERON:feces	no	15.34	None	stool	2/13/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8712	121980	408170	BI	.1,g	E1	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121980	8712 stool	CCFA_RISK
121982.1246173	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153006	30.0	None	10/8/82	human	0	9606	MiSeq	human gut metagenome	female	no	1	UBERON:feces	no	15.34	None	stool	2/5/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8582	121982	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121982	8582 stool	CCFA_RISK
SKBTI.1334.1247137	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162483	13.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	None	15.34	None	biopsy	10/12/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0844	SKBTI.1334	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1334	M1-0844 biopsy	CCFA_RISK
121976.1247220	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153023	22.0	None	1/17/90	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:feces	no	15.34	None	stool	12/12/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8600	121976	408170	BI	.1,g	E3	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	121976	8600 stool	CCFA_RISK
SKBTI.1126.1246316	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162335	10.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	8/2/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0336	SKBTI.1126	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1126	M1-0336 biopsy	CCFA_RISK
122033.1246288	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153024	22.0	None	1/17/90	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:feces	no	15.34	None	stool	1/10/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8600	122033	408170	BI	.1,g	E3	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	122033	8600 stool	CCFA_RISK
100102.1246796	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125855	62.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100102	100102	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100102	OR100102 stool	CCFA_RISK
122079.1246313	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153026	23.0	None	9/26/89	human	0	9606	MiSeq	human gut metagenome	male	no	1	UBERON:feces	no	15.34	None	stool	10/9/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8603	122079	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122079	8603 stool	CCFA_RISK
121455.1246836	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136279	26.0	None	7/4/84	human	0	9606	MiSeq	human gut metagenome	male	no	2	UBERON:feces	no	15.34	None	stool	10/28/10	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8096	121455	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121455	8096 stool	CCFA_RISK
SKBTI.0261.1246330	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136014	12.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/21/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0687	SKBTI.0261	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0261	M1-0687 biopsy	CCFA_RISK
SKBTI.0558.1247236	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133693	12.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/8/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0544	SKBTI.0558	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0558	M1-0544 biopsy	CCFA_RISK
SKBTI.0615.1246962	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133750	16.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	7/11/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0438	SKBTI.0615	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0615	M1-0438 biopsy	CCFA_RISK
SKBTI.1341.1246655	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162485	16.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	10/17/11	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0757	SKBTI.1341	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1341	M1-0757 biopsy	CCFA_RISK
121959.1247341	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153056	31.0	None	12/4/81	human	0	9606	MiSeq	human gut metagenome	male	no	6	UBERON:feces	no	15.34	None	stool	1/23/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8700	121959	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121959	8700 stool	CCFA_RISK
SKBTI.0730.1247082	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135648	8.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	12/8/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0557	SKBTI.0730	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0730	M1-0557 biopsy	CCFA_RISK
SKBTI053.1246431	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106924	15.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	1/24/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0653	SKBTI053	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI053	M1-0653 biopsy	CCFA_RISK
SKBTI.0606.1246635	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133741	10.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/28/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0437	SKBTI.0606	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0606	M1-0437 biopsy	CCFA_RISK
SKBTI.0974.1246790	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162402	13.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:cecum	no	15.34	None	biopsy	11/5/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0027	SKBTI.0974	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0974	M1-0027 biopsy	CCFA_RISK
SKBTI096.1247388	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-107059	5.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	11/2/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0065	SKBTI096	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI096	M1-0065 biopsy	CCFA_RISK
SKBTI.0683.1247039	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135695	10.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	5/18/12	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0476	SKBTI.0683	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0683	M1-0476 biopsy	CCFA_RISK
SKBTI.0158.1246412	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123009	12.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/28/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0307	SKBTI.0158	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0158	M1-0307 biopsy	CCFA_RISK
122049.1246753	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153005	30.0	None	10/8/82	human	0	9606	MiSeq	human gut metagenome	female	no	1	UBERON:feces	no	15.34	None	stool	11/27/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8582	122049	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122049	8582 stool	CCFA_RISK
SKBTI.1069.1246203	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161035	16.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:colon	no	15.34	None	biopsy	10/19/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0501	SKBTI.1069	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Transverse colon	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1069	M1-0501 biopsy	CCFA_RISK
121281.1246713	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136330	25.0	None	3/30/87	human	0	9606	MiSeq	human gut metagenome	female	no	9	UBERON:feces	yes	15.34	None	stool	8/28/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8587	121281	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121281	8587 stool	CCFA_RISK
SKBTI.0584.1247349	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133719	7.416666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/22/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0603	SKBTI.0584	408170	BI	.1,g	L3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0584	M1-0603 biopsy	CCFA_RISK
100206.1246938	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127129	53.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100206	100206	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100206	OR100206 stool	CCFA_RISK
SKBTI.0133.1247396	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122985	6.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	8/26/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0482	SKBTI.0133	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0133	M1-0482 biopsy	CCFA_RISK
SKBTI.0249.1246163	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123104	13.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	None	15.34	None	biopsy	3/7/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0686	SKBTI.0249	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0249	M1-0686 biopsy	CCFA_RISK
121448.1246595	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136365	29.0	None	9/23/82	human	0	9606	MiSeq	human gut metagenome	female	None	9	UBERON:feces	None	15.34	None	stool	7/2/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8567	121448	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	121448	8567 stool	CCFA_RISK
SKBTI.0621.1246627	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133756	8.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/13/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0142	SKBTI.0621	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0621	M1-0142 biopsy	CCFA_RISK
SKBTI.0613.1246236	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133748	13.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/7/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0334	SKBTI.0613	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0613	M1-0334 biopsy	CCFA_RISK
SKBTI.0705.1247060	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135624	13.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	9/7/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0584	SKBTI.0705	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0705	M1-0584 biopsy	CCFA_RISK
SKBTI.0988.1247352	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162412	13.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:colon	no	15.34	None	biopsy	1/22/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0812	SKBTI.0988	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Ascending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0988	M1-0812 biopsy	CCFA_RISK
121185.1247360	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136302	31.0	None	10/15/80	human	0	9606	MiSeq	human gut metagenome	male	no	12	UBERON:feces	no	15.34	None	stool	3/14/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8474	121185	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121185	8474 stool	CCFA_RISK
SKBTI.0272.1247054	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136006	15.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	4/1/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0538	SKBTI.0272	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0272	M1-0538 biopsy	CCFA_RISK
SKBTI.0596.1246518	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133731	13.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	None	15.34	None	biopsy	6/27/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0670	SKBTI.0596	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0596	M1-0670 biopsy	CCFA_RISK
SKBTI.0672.1246496	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155035	10.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	2/14/12	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0056	SKBTI.0672	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0672	M1-0056 biopsy	CCFA_RISK
121216.1247056	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136323	45.0	None	8/19/66	human	0	9606	MiSeq	human gut metagenome	female	no	19	UBERON:feces	no	15.34	None	stool	8/13/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8523	121216	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121216	8523 stool	CCFA_RISK
SKBTI.0740.1246520	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135654	13.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/7/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0416	SKBTI.0740	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0740	M1-0416 biopsy	CCFA_RISK
SKBTI.0957.1246483	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147061	10.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	2/8/12	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0548	SKBTI.0957	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0957	M1-0548 biopsy	CCFA_RISK
SKBTI.0555.1246287	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133690	4.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	6/2/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0328	SKBTI.0555	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0555	M1-0328 biopsy	CCFA_RISK
SKBTI077.1246715	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106948	8.666666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	1/24/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0398	SKBTI077	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI077	M1-0398 biopsy	CCFA_RISK
SKBTI.0150.1246990	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123002	12.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	10/27/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0596	SKBTI.0150	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0150	M1-0596 biopsy	CCFA_RISK
SKBTI.1171.1246681	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161085	13.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:colon	no	15.34	None	biopsy	7/25/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0781	SKBTI.1171	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Ascending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1171	M1-0781 biopsy	CCFA_RISK
122063.1246844	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153034	23.0	None	2/13/89	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:feces	no	15.34	None	stool	1/8/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8646	122063	408170	BI	.1,g	E1	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	122063	8646 stool	CCFA_RISK
SKBTI.0766.1246308	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135679	8.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	9/9/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0563	SKBTI.0766	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0766	M1-0563 biopsy	CCFA_RISK
SKBTI.1026.1246716	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161145	9.333333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	7/19/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0576	SKBTI.1026	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1026	M1-0576 biopsy	CCFA_RISK
122061.1246318	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153077	22.0	None	2/14/91	human	0	9606	MiSeq	human gut metagenome	male	no	1	UBERON:feces	no	15.34	None	stool	2/25/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Current	PRISM	1939:8678	122061	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	122061	8678 stool	CCFA_RISK
SKBTI.0576.1246806	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133657	6.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/17/11	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0054	SKBTI.0576	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0576	M1-0054 biopsy	CCFA_RISK
100096.1247401	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125851	18.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100096	100096	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100096	OR100096 stool	CCFA_RISK
MGH105126.1246485	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125889	26.0	yes	1/10/82	human	0	9606	MiSeq	human gut metagenome	female	no	4	UBERON:rectum	no	15.34	None	biopsy	11/12/08	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7355	MGH105126	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH105126	7355 biopsy	CCFA_RISK
SKBTI012.1246804	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127157	7.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/5/09	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0023	SKBTI012	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI012	M1-0023 biopsy	CCFA_RISK
SKBTI046.1246305	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106917	16.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/27/10	0.0	no	ENVO:urban biome	None	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0168	SKBTI046	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI046	M1-0168 biopsy	CCFA_RISK
SKBTI.0969.1246876	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162399	12.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	9/24/09	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0746	SKBTI.0969	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0969	M1-0746 biopsy	CCFA_RISK
SKBTI.1306.1247356	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161190	9.166666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	5/2/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0156	SKBTI.1306	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1306	M1-0156 biopsy	CCFA_RISK
SKBTI.1014.1247306	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161136	15.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	None	15.34	None	biopsy	5/17/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0385	SKBTI.1014	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1014	M1-0385 biopsy	CCFA_RISK
SKBTI028.1246818	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106899	13.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/5/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0016	SKBTI028	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI028	M1-0016 biopsy	CCFA_RISK
SKBTI.0538.1247331	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133673	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/31/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0129	SKBTI.0538	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0538	M1-0129 biopsy	CCFA_RISK
SKBTI.0494.1246364	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133629	6.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/14/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0458	SKBTI.0494	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0494	M1-0458 biopsy	CCFA_RISK
SKBTI.1045.1247193	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161160	16.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	9/15/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0083	SKBTI.1045	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1045	M1-0083 biopsy	CCFA_RISK
SKBTI.0192.1246404	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123040	9.333333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	7/19/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0576	SKBTI.0192	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0192	M1-0576 biopsy	CCFA_RISK
SKBTI.0167.1247157	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123017	10.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/13/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0549	SKBTI.0167	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0167	M1-0549 biopsy	CCFA_RISK
SKBTI.0227.1247270	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135995	None	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	None	15.34	None	biopsy	3/15/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0357	SKBTI.0227	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0227	M1-0357 biopsy	CCFA_RISK
121493.1247335	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136414	29.0	None	1/11/82	human	0	9606	MiSeq	human gut metagenome	female	no	20	UBERON:feces	yes	15.34	None	stool	6/22/11	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8336	121493	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B2	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121493	8336 stool	CCFA_RISK
121464.1246138	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136288	31.0	None	7/27/78	human	0	9606	MiSeq	human gut metagenome	female	no	13	UBERON:feces	yes	15.34	None	stool	4/12/10	0.0	None	ENVO:urban biome	None	Illumina	None	african	BI	GAZ:United States of America	Never	PRISM	1939:7941	121464	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121464	7941 stool	CCFA_RISK
SKBTI.1166.1247021	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162347	10.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	7/22/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0831	SKBTI.1166	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1166	M1-0831 biopsy	CCFA_RISK
SKBTI.1264.1247153	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161175	11.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:cecum	no	15.34	None	biopsy	4/26/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0600	SKBTI.1264	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1264	M1-0600 biopsy	CCFA_RISK
121192.1247127	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136309	34.0	None	8/14/77	human	0	9606	MiSeq	human gut metagenome	male	no	9	UBERON:feces	no	15.34	None	stool	3/21/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8480	121192	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121192	8480 stool	CCFA_RISK
SKBTI.1084.1247144	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162311	15.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	11/30/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0265	SKBTI.1084	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1084	M1-0265 biopsy	CCFA_RISK
SKBTI061.1247050	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106932	14.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/6/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0033	SKBTI061	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI061	M1-0033 biopsy	CCFA_RISK
SKBTI.0552.1246197	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133687	14.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/30/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0697	SKBTI.0552	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0552	M1-0697 biopsy	CCFA_RISK
SKBTI.0210.1246599	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123066	13.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	1/28/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0299	SKBTI.0210	408170	BI	.1,g	L1	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0210	M1-0299 biopsy	CCFA_RISK
SKBTI.1134.1246714	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161067	11.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	yes	15.34	None	biopsy	8/2/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0817	SKBTI.1134	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1134	M1-0817 biopsy	CCFA_RISK
SKBTI.1204.1246618	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162370	13.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	9/28/10	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0038	SKBTI.1204	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1204	M1-0038 biopsy	CCFA_RISK
122050.1246161	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153016	38.0	None	5/31/74	human	0	9606	MiSeq	human gut metagenome	male	no	1	UBERON:feces	yes	15.34	None	stool	10/26/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8585	122050	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122050	8585 stool	CCFA_RISK
100075.1246833	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125836	19.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100075	100075	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	yes	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100075	OR100075 stool	CCFA_RISK
SKBTI.0234.1246423	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123089	8.416666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	1/12/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0429	SKBTI.0234	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0234	M1-0429 biopsy	CCFA_RISK
SKBTI.0274.1246503	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123144	12.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/30/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0118	SKBTI.0274	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0274	M1-0118 biopsy	CCFA_RISK
121457.1247318	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136281	45.0	None	4/29/65	human	0	9606	MiSeq	human gut metagenome	male	no	26	UBERON:feces	yes	15.34	None	stool	12/17/10	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:7875	121457	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B2	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121457	7875 stool	CCFA_RISK
SKBTI.0991.1247254	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161121	12.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	yes	15.34	None	biopsy	12/11/09	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0774	SKBTI.0991	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0991	M1-0774 biopsy	CCFA_RISK
SKBTI.0675.1246665	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135687	1.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/27/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0153	SKBTI.0675	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0675	M1-0153 biopsy	CCFA_RISK
MGH100601.1247089	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125768	27.0	yes	9/9/79	human	0	9606	MiSeq	human gut metagenome	female	no	6	UBERON:colon	no	15.34	None	biopsy	8/1/07	0.0	yes	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7111	MGH100601	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	yes	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH100601	7111 biopsy	CCFA_RISK
SKBTI.1245.1246863	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162392	12.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/5/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0432	SKBTI.1245	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1245	M1-0432 biopsy	CCFA_RISK
SKBTI.0973.1246509	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162401	5.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:colon	no	15.34	None	biopsy	2/15/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0224	SKBTI.0973	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0973	M1-0224 biopsy	CCFA_RISK
SKBTI.1097.1246573	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161047	11.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	7/25/11	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0466	SKBTI.1097	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1097	M1-0466 biopsy	CCFA_RISK
100091.1247210	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125848	23.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100091	100091	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100091	OR100091 stool	CCFA_RISK
SKBTI025.1247326	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106896	10.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	3/29/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0233	SKBTI025	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI025	M1-0233 biopsy	CCFA_RISK
SKBTI.1202.1246546	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162368	4.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	None	15.34	None	biopsy	2/9/12	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0786	SKBTI.1202	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1202	M1-0786 biopsy	CCFA_RISK
MGH105234.1246894	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125747	34.0	no	1/15/74	human	0	9606	MiSeq	human gut metagenome	male	no	13	UBERON:ileum	no	15.34	None	biopsy	11/19/08	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	None	BI	GAZ:United States of America	Never	PRISM	1939:7022	MGH105234	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B3	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH105234	7022 biopsy	CCFA_RISK
122060.1246740	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153002	29.0	None	10/8/82	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:feces	no	15.34	None	stool	8/22/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8582	122060	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122060	8582 stool	CCFA_RISK
SKBTI.0611.1246512	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133746	4.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	7/6/11	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0141	SKBTI.0611	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0611	M1-0141 biopsy	CCFA_RISK
100198.1246877	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127123	40.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100198	100198	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100198	OR100198 stool	CCFA_RISK
121199.1246159	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136316	30.0	None	8/7/81	human	0	9606	MiSeq	human gut metagenome	female	no	11	UBERON:feces	yes	15.34	None	stool	5/23/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8527	121199	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B2	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121199	8527 stool	CCFA_RISK
SKBTI.0997.1246861	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161125	16.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/7/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0305	SKBTI.0997	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0997	M1-0305 biopsy	CCFA_RISK
SKBTI.1042.1246604	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161158	15.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	11/10/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0598	SKBTI.1042	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1042	M1-0598 biopsy	CCFA_RISK
SKBTI.0921.1247351	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147025	6.333333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	yes	15.34	None	biopsy	2/28/12	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0379	SKBTI.0921	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0921	M1-0379 biopsy	CCFA_RISK
MGH103687.1246642	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125758	57.0	no	2/25/51	human	0	9606	MiSeq	human gut metagenome	female	no	40	UBERON:colon	no	15.34	None	biopsy	6/18/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7265	MGH103687	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH103687	7265 biopsy	CCFA_RISK
SKBTI.0217.1247447	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123073	15.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	2/24/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0227	SKBTI.0217	408170	BI	.1,g	L1	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0217	M1-0227 biopsy	CCFA_RISK
SKBTI.1012.1246610	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161134	16.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	5/10/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0747	SKBTI.1012	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1012	M1-0747 biopsy	CCFA_RISK
SKBTI.0763.1246872	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135676	10.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	6/14/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0364	SKBTI.0763	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0763	M1-0364 biopsy	CCFA_RISK
121954.1247208	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153084	31.0	None	12/4/81	human	0	9606	MiSeq	human gut metagenome	male	no	6	UBERON:feces	no	15.34	None	stool	1/23/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8700	121954	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121954	8700 stool	CCFA_RISK
SKBTI.0175.1246294	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136073	15.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	5/26/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0363	SKBTI.0175	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0175	M1-0363 biopsy	CCFA_RISK
SKBTI.0983.1247361	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161118	14.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:cecum	no	15.34	None	biopsy	9/14/09	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0064	SKBTI.0983	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0983	M1-0064 biopsy	CCFA_RISK
SKBTI.0196.1247109	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123054	11.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	None	15.34	None	biopsy	2/25/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0382	SKBTI.0196	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0196	M1-0382 biopsy	CCFA_RISK
122011.1246363	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153036	41.0	None	10/16/71	human	0	9606	MiSeq	human gut metagenome	female	no	17	UBERON:feces	no	15.34	None	stool	12/17/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8647	122011	408170	BI	.1,g	J-Pouch	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122011	8647 stool	CCFA_RISK
SKBTI082.1247043	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127154	14.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/16/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0243	SKBTI082	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI082	M1-0243 biopsy	CCFA_RISK
SKBTI.0260.1247152	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123115	12.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/17/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0536	SKBTI.0260	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0260	M1-0536 biopsy	CCFA_RISK
SKBTI.0102.1247000	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135930	4.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	1/20/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0202	SKBTI.0102	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0102	M1-0202 biopsy	CCFA_RISK
100088.1246120	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125845	29.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100088	100088	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100088	OR100088 stool	CCFA_RISK
100051.1247218	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125825	36.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100051	100051	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100051	OR100051 stool	CCFA_RISK
SKBTI.1078.1246823	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162307	10.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	12/22/08	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0713	SKBTI.1078	408170	BI	.1,g	L1	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1078	M1-0713 biopsy	CCFA_RISK
SKBTI.1253.1246606	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161168	9.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/2/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0710	SKBTI.1253	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1253	M1-0710 biopsy	CCFA_RISK
122039.1246202	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153065	21.0	None	8/2/91	human	0	9606	MiSeq	human gut metagenome	female	yes	1	UBERON:feces	yes	15.34	None	stool	1/29/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8649	122039	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122039	8649 stool	CCFA_RISK
SKBTI.0245.1247452	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135997	8.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/7/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0685	SKBTI.0245	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0245	M1-0685 biopsy	CCFA_RISK
SKBTI.1092.1246638	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162318	7.416666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	12/13/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0395	SKBTI.1092	408170	BI	.1,g	L2	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.1092	M1-0395 biopsy	CCFA_RISK
SKBTI.0569.1247213	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133807	12.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	12/9/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0426	SKBTI.0569	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0569	M1-0426 biopsy	CCFA_RISK
121449.1246322	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136366	53.0	None	12/16/58	human	0	9606	MiSeq	human gut metagenome	female	no	18	UBERON:feces	no	15.34	None	stool	6/25/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8565	121449	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121449	8565 stool	CCFA_RISK
SKBTI.1192.1247336	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162361	3.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/25/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0769	SKBTI.1192	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1192	M1-0769 biopsy	CCFA_RISK
SKBTI.0283.1247094	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123137	13.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/10/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0396	SKBTI.0283	408170	BI	.1,g	L1	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0283	M1-0396 biopsy	CCFA_RISK
SKBTI.0688.1246780	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135700	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	7/2/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0245	SKBTI.0688	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0688	M1-0245 biopsy	CCFA_RISK
122001.1246615	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153028	41.0	None	5/1/71	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:feces	no	15.34	None	stool	11/13/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8636	122001	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	122001	8636 stool	CCFA_RISK
121454.1246786	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136278	21.0	None	8/18/89	human	0	9606	MiSeq	human gut metagenome	male	no	1	UBERON:feces	no	15.34	None	stool	11/30/10	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8106	121454	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121454	8106 stool	CCFA_RISK
SKBTI.0126.1247399	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122978	8.333333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	9/24/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0296	SKBTI.0126	408170	BI	.1,g	L3	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0126	M1-0296 biopsy	CCFA_RISK
MGH101187.1247389	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125787	43.0	yes	7/10/64	human	0	9606	MiSeq	human gut metagenome	female	no	5	UBERON:cecum	no	15.34	None	biopsy	10/4/07	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7174	MGH101187	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH101187	7174 biopsy	CCFA_RISK
SKBTI.0646.1246846	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133781	14.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	yes	15.34	None	biopsy	6/18/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0244	SKBTI.0646	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0646	M1-0244 biopsy	CCFA_RISK
SKBTI.0526.1246560	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133661	5.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/25/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0387	SKBTI.0526	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0526	M1-0387 biopsy	CCFA_RISK
SKBTI.1285.1246958	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161182	12.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:colon	no	15.34	None	biopsy	8/25/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0470	SKBTI.1285	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1285	M1-0470 biopsy	CCFA_RISK
SKBTI.0200.1246259	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123057	7.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	1/24/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0397	SKBTI.0200	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0200	M1-0397 biopsy	CCFA_RISK
SKBTI.1280.1246994	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161178	12.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	8/23/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0287	SKBTI.1280	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1280	M1-0287 biopsy	CCFA_RISK
100058.1247305	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125827	21.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100058	100058	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100058	OR100058 stool	CCFA_RISK
MGH103912.1247006	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125748	45.0	no	6/24/63	human	0	9606	MiSeq	human gut metagenome	male	no	18	UBERON:colon	yes	15.34	None	biopsy	7/1/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7035	MGH103912	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	yes	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Transverse colon	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH103912	7035 biopsy	CCFA_RISK
SKBTI.0999.1246492	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161127	10.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/13/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0549	SKBTI.0999	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0999	M1-0549 biopsy	CCFA_RISK
SKBTI.0223.1247281	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123143	14.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	yes	15.34	None	biopsy	3/3/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0229	SKBTI.0223	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0223	M1-0229 biopsy	CCFA_RISK
100200.1246541	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127124	35.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	2	OSCCAR	1939:OR100200	100200	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100200	OR100200 stool	CCFA_RISK
MGH102271.1246470	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125880	42.0	no	6/26/65	human	0	9606	MiSeq	human gut metagenome	female	yes	3	UBERON:colon	no	15.34	None	biopsy	2/26/08	0.0	yes	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7178	MGH102271	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	yes	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Transverse colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH102271	7178 biopsy	CCFA_RISK
SKBTI.0889.1246530	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146993	15.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	yes	15.34	None	biopsy	5/24/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0696	SKBTI.0889	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0889	M1-0696 biopsy	CCFA_RISK
SKBTI.0653.1246736	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133788	12.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/27/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0547	SKBTI.0653	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0653	M1-0547 biopsy	CCFA_RISK
SKBTI.0976.1246407	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162404	13.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:cecum	no	15.34	None	biopsy	11/5/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0027	SKBTI.0976	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0976	M1-0027 biopsy	CCFA_RISK
SKBTI.0262.1246176	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155005	15.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/21/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0319	SKBTI.0262	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0262	M1-0319 biopsy	CCFA_RISK
SKBTI.0304.1247385	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29E7.1.Solexa-124667	15.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	2/1/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0109	SKBTI.0304	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0304	M1-0109 biopsy	CCFA_RISK
SKBTI.0888.1247295	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146992	10.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	2/25/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0533	SKBTI.0888	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0888	M1-0533 biopsy	CCFA_RISK
SKBTI.0667.1246339	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133718	11.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	None	15.34	None	biopsy	8/23/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0389	SKBTI.0667	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0667	M1-0389 biopsy	CCFA_RISK
121498.1246290	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136418	71.0	None	4/13/41	human	0	9606	MiSeq	human gut metagenome	male	no	20	UBERON:feces	no	15.34	None	stool	10/16/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8628	121498	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121498	8628 stool	CCFA_RISK
SKBTI.0488.1246639	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133708	16.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	4/13/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0120	SKBTI.0488	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0488	M1-0120 biopsy	CCFA_RISK
SKBTI.1116.1247309	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161057	9.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	yes	15.34	None	biopsy	7/26/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0822	SKBTI.1116	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1116	M1-0822 biopsy	CCFA_RISK
122053.1247029	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153079	67.0	None	5/22/45	human	0	9606	MiSeq	human gut metagenome	male	no	51	UBERON:feces	no	15.34	None	stool	1/10/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8692	122053	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	122053	8692 stool	CCFA_RISK
SKBTI.0910.1246537	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147014	9.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/2/12	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0710	SKBTI.0910	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0910	M1-0710 biopsy	CCFA_RISK
SKBTI.0715.1246268	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135633	14.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	9/23/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	east_asian	BI	GAZ:United States of America	None	RISK	1939:M1-0472	SKBTI.0715	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0715	M1-0472 biopsy	CCFA_RISK
SKBTI.0128.1246922	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122980	13.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	10/7/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0350	SKBTI.0128	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0128	M1-0350 biopsy	CCFA_RISK
SKBTI076.1247100	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106947	9.416666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/1/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0166	SKBTI076	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI076	M1-0166 biopsy	CCFA_RISK
122100.1247161	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153045	21.0	None	8/2/91	human	0	9606	MiSeq	human gut metagenome	female	yes	1	UBERON:feces	yes	15.34	None	stool	3/4/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8649	122100	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122100	8649 stool	CCFA_RISK
SKBTI.0250.1246980	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136004	14.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	3/10/11	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0112	SKBTI.0250	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0250	M1-0112 biopsy	CCFA_RISK
SKBTI.0893.1246194	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146997	14.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	5/30/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0697	SKBTI.0893	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0893	M1-0697 biopsy	CCFA_RISK
SKBTI023.1246430	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106894	7.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	2/20/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0013	SKBTI023	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI023	M1-0013 biopsy	CCFA_RISK
SKBTI.0952.1247368	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147056	12.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	3/2/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0316	SKBTI.0952	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0952	M1-0316 biopsy	CCFA_RISK
120153.1246821	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127150	22.0	None	12/22/87	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	2/11/10	0.0	None	ENVO:urban biome	None	Illumina	None	other	BI	GAZ:United States of America	Never	PRISM	1939:7847	120153	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	None	no	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	120153	7847 stool	CCFA_RISK
SKBTI033.1247139	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106904	9.166666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/29/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0209	SKBTI033	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI033	M1-0209 biopsy	CCFA_RISK
SKBTI075.1246200	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127160	10.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	8/5/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0349	SKBTI075	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI075	M1-0349 biopsy	CCFA_RISK
SKBTI.0666.1246852	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133713	16.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	8/18/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0481	SKBTI.0666	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0666	M1-0481 biopsy	CCFA_RISK
MGH102386.1246679	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125782	47.0	no	1/8/61	human	0	9606	MiSeq	human gut metagenome	female	no	13	UBERON:cecum	yes	15.34	None	biopsy	3/4/08	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7154	MGH102386	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH102386	7154 biopsy	CCFA_RISK
121473.1247472	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136401	22.0	None	3/15/89	human	0	9606	MiSeq	human gut metagenome	female	no	13	UBERON:feces	no	15.34	None	stool	6/29/11	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8345	121473	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121473	8345 stool	CCFA_RISK
SKBTI.0544.1246933	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133679	8.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/23/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0327	SKBTI.0544	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0544	M1-0327 biopsy	CCFA_RISK
SKBTI.1088.1246462	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162315	16.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:cecum	no	15.34	None	biopsy	12/6/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0839	SKBTI.1088	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1088	M1-0839 biopsy	CCFA_RISK
SKBTI035.1246985	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106906	13.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	2/25/10	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	other	BI	GAZ:United States of America	None	RISK	1939:M1-0228	SKBTI035	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI035	M1-0228 biopsy	CCFA_RISK
SKBTI.0107.1246579	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122962	10.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/15/09	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0201	SKBTI.0107	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0107	M1-0201 biopsy	CCFA_RISK
MGH110455.1247279	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125735	51.0	no	4/2/58	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:colon	None	15.34	None	biopsy	9/21/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	None	PRISM	1939:7664	MGH110455	408170	BI	.1,g	None	years	1939	control	study of normal and IBD samples	no	control	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	control	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	MGH110455	biopsy 7664	CCFA_RISK
SKBTI.0155.1246919	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123006	10.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	9/17/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	arab	BI	GAZ:United States of America	None	RISK	1939:M1-0499	SKBTI.0155	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0155	M1-0499 biopsy	CCFA_RISK
SKBTI070.1246206	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106941	7.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	2/8/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0412	SKBTI070	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI070	M1-0412 biopsy	CCFA_RISK
SKBTI.0706.1246831	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135625	16.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	9/19/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0585	SKBTI.0706	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0706	M1-0585 biopsy	CCFA_RISK
SKBTI.1051.1246225	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162430	14.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	9/22/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0620	SKBTI.1051	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1051	M1-0620 biopsy	CCFA_RISK
SKBTI.0641.1246956	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133776	3.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/16/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0464	SKBTI.0641	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0641	M1-0464 biopsy	CCFA_RISK
121499.1247002	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136419	28.0	None	12/7/83	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:feces	no	15.34	None	stool	10/14/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8641	121499	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121499	8641 stool	CCFA_RISK
SKBTI.1146.1246654	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162435	14.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	8/15/11	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0754	SKBTI.1146	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1146	M1-0754 biopsy	CCFA_RISK
SKBTI.0524.1247451	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133659	14.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/6/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0246	SKBTI.0524	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0524	M1-0246 biopsy	CCFA_RISK
SKBTI080.1246769	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106951	9.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	12/11/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0160	SKBTI080	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI080	M1-0160 biopsy	CCFA_RISK
SKBTI.0444.1246275	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-154992	15.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	4/8/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0348	SKBTI.0444	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0444	M1-0348 biopsy	CCFA_RISK
SKBTI.0636.1246335	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133771	9.083333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/10/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0418	SKBTI.0636	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0636	M1-0418 biopsy	CCFA_RISK
121469.1246137	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136369	57.0	None	11/15/53	human	0	9606	MiSeq	human gut metagenome	female	no	8	UBERON:feces	no	15.34	None	stool	5/4/11	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:7421	121469	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121469	7421 stool	CCFA_RISK
SKBTI.0148.1246192	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123000	12.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	10/18/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0084	SKBTI.0148	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0148	M1-0084 biopsy	CCFA_RISK
SKBTI.1282.1246682	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161179	11.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	8/24/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0801	SKBTI.1282	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1282	M1-0801 biopsy	CCFA_RISK
SKBTI.0125.1247196	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122977	15.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	yes	15.34	None	biopsy	9/11/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0215	SKBTI.0125	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0125	M1-0215 biopsy	CCFA_RISK
SKBTI051.1246945	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106922	15.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/25/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0232	SKBTI051	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI051	M1-0232 biopsy	CCFA_RISK
SKBTI.1223.1247448	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162377	9.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	8/23/11	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0762	SKBTI.1223	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1223	M1-0762 biopsy	CCFA_RISK
SKBTI.0514.1246749	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133649	15.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/3/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0540	SKBTI.0514	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0514	M1-0540 biopsy	CCFA_RISK
MGH101010.1246829	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125779	30.0	no	6/2/77	human	0	9606	MiSeq	human gut metagenome	male	no	4	UBERON:ileum	no	15.34	None	biopsy	9/18/07	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7141	MGH101010	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B3	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH101010	7141 biopsy	CCFA_RISK
SKBTI.0925.1247367	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147029	15.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	9/22/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0439	SKBTI.0925	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0925	M1-0439 biopsy	CCFA_RISK
121183.1246254	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136300	21.0	None	6/1/90	human	0	9606	MiSeq	human gut metagenome	female	no	6	UBERON:feces	no	15.34	None	stool	3/12/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8470	121183	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121183	8470 stool	CCFA_RISK
SKBTI.0994.1246822	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162415	9.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	3/3/10	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0384	SKBTI.0994	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0994	M1-0384 biopsy	CCFA_RISK
SKBTI.0674.1246315	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135686	13.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	12/9/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0708	SKBTI.0674	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0674	M1-0708 biopsy	CCFA_RISK
122098.1246463	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153088	30.0	None	10/13/82	human	0	9606	MiSeq	human gut metagenome	female	no	11	UBERON:feces	no	15.34	None	stool	3/1/13	0.0	None	ENVO:urban biome	None	Illumina	None	other	BI	GAZ:United States of America	Never	PRISM	1939:8726	122098	408170	BI	.1,g	J-Pouch	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B2	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122098	8726 stool	CCFA_RISK
SKBTI.0947.1246381	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147051	15.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	yes	15.34	None	biopsy	11/30/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	east_asian	BI	GAZ:United States of America	None	RISK	1939:M1-0502	SKBTI.0947	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0947	M1-0502 biopsy	CCFA_RISK
SKBTI030.1247289	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106901	10.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	8/3/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0562	SKBTI030	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI030	M1-0562 biopsy	CCFA_RISK
SKBTI.0963.1246653	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162396	13.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:colon	no	15.34	None	biopsy	10/1/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0718	SKBTI.0963	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0963	M1-0718 biopsy	CCFA_RISK
SKBTI.1284.1247147	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161181	12.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:colon	no	15.34	None	biopsy	8/25/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0470	SKBTI.1284	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1284	M1-0470 biopsy	CCFA_RISK
SKBTI.0252.1246170	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123107	15.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	3/14/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0113	SKBTI.0252	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0252	M1-0113 biopsy	CCFA_RISK
SKBTI089.1247099	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106960	5.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	9/16/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0588	SKBTI089	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI089	M1-0588 biopsy	CCFA_RISK
100225.1246548	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127143	27.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	2	OSCCAR	1939:OR100225	100225	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	yes	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100225	OR100225 stool	CCFA_RISK
SKBTI.1054.1247185	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162432	6.083333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	10/1/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0553	SKBTI.1054	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.1054	M1-0553 biopsy	CCFA_RISK
SKBTI.1006.1246720	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162419	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	3/24/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0303	SKBTI.1006	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.1006	M1-0303 biopsy	CCFA_RISK
SKBTI.1144.1246149	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162434	14.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:cecum	no	15.34	None	biopsy	8/15/11	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0754	SKBTI.1144	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1144	M1-0754 biopsy	CCFA_RISK
121463.1246219	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136287	38.0	None	2/21/72	human	0	9606	MiSeq	human gut metagenome	female	None	21	UBERON:feces	None	15.34	None	stool	4/6/10	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:7932	121463	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	121463	7932 stool	CCFA_RISK
122039.1247121	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153040	21.0	None	8/2/91	human	0	9606	MiSeq	human gut metagenome	female	yes	1	UBERON:feces	yes	15.34	None	stool	1/29/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8649	122039	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122039	8649 stool	CCFA_RISK
121952.1246340	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153055	31.0	None	12/4/81	human	0	9606	MiSeq	human gut metagenome	male	no	6	UBERON:feces	no	15.34	None	stool	1/23/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8700	121952	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121952	8700 stool	CCFA_RISK
SKBTI.0311.1246585	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29E7.1.Solexa-124674	6.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	2/28/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0485	SKBTI.0311	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B3	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0311	M1-0485 biopsy	CCFA_RISK
SKBTI.0600.1247446	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133735	11.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/29/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0138	SKBTI.0600	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0600	M1-0138 biopsy	CCFA_RISK
SKBTI.0716.1246727	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135634	15.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	9/27/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0625	SKBTI.0716	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0716	M1-0625 biopsy	CCFA_RISK
SKBTI.0392.1246534	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-154985	14.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	8/5/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0496	SKBTI.0392	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0392	M1-0496 biopsy	CCFA_RISK
SKBTI.0490.1246843	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133625	7.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/11/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0372	SKBTI.0490	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0490	M1-0372 biopsy	CCFA_RISK
121181.1246741	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136298	41.0	None	1/25/71	human	0	9606	MiSeq	human gut metagenome	male	no	13	UBERON:feces	no	15.34	None	stool	3/7/12	0.0	None	ENVO:urban biome	None	Illumina	None	other	BI	GAZ:United States of America	Never	PRISM	1939:8462	121181	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121181	8462 stool	CCFA_RISK
SKBTI.0762.1247378	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155061	4.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	1/26/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0106	SKBTI.0762	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0762	M1-0106 biopsy	CCFA_RISK
SKBTI.0651.1246810	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133786	12.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/5/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0432	SKBTI.0651	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0651	M1-0432 biopsy	CCFA_RISK
100219.1247117	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127138	50.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100219	100219	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100219	OR100219 stool	CCFA_RISK
122119.1247014	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153068	21.0	None	8/2/91	human	0	9606	MiSeq	human gut metagenome	female	yes	1	UBERON:feces	yes	15.34	None	stool	3/4/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8649	122119	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122119	8649 stool	CCFA_RISK
SKBTI.0614.1246948	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133749	15.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/6/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0433	SKBTI.0614	408170	BI	.1,g	L3	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0614	M1-0433 biopsy	CCFA_RISK
SKBTI.0891.1246968	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146995	13.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	5/26/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0569	SKBTI.0891	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0891	M1-0569 biopsy	CCFA_RISK
SKBTI.1315.1246136	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162477	9.666666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/10/12	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0737	SKBTI.1315	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1315	M1-0737 biopsy	CCFA_RISK
SKBTI018.1246212	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106889	12.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	9/8/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0368	SKBTI018	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI018	M1-0368 biopsy	CCFA_RISK
MGH100896.1247342	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136031	34.0	yes	2/16/73	human	0	9606	MiSeq	human gut metagenome	female	no	6	UBERON:ileum	no	15.34	None	biopsy	9/11/07	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7094	MGH100896	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B3	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH100896	7094 biopsy	CCFA_RISK
SKBTI.0557.1246763	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133692	6.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/21/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0507	SKBTI.0557	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0557	M1-0507 biopsy	CCFA_RISK
SKBTI.0758.1246673	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155058	10.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	6/16/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0036	SKBTI.0758	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0758	M1-0036 biopsy	CCFA_RISK
SKBTI.0143.1246531	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122995	11.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	8/16/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0498	SKBTI.0143	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0143	M1-0498 biopsy	CCFA_RISK
SKBTI.1033.1246475	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161151	9.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	11/3/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0369	SKBTI.1033	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1033	M1-0369 biopsy	CCFA_RISK
SKBTI.0749.1246228	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135663	15.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	3/25/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0232	SKBTI.0749	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0749	M1-0232 biopsy	CCFA_RISK
121400.1246372	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136351	46.0	None	12/19/65	human	0	9606	MiSeq	human gut metagenome	female	no	8	UBERON:feces	no	15.34	None	stool	10/2/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Current	PRISM	1939:8488	121400	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121400	8488 stool	CCFA_RISK
SKBTI.0915.1247359	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147019	16.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	10/7/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	arab	BI	GAZ:United States of America	None	RISK	1939:M1-0707	SKBTI.0915	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0915	M1-0707 biopsy	CCFA_RISK
121217.1246974	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136324	57.0	None	4/18/55	human	0	9606	MiSeq	human gut metagenome	male	no	17	UBERON:feces	no	15.34	None	stool	6/11/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8534	121217	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121217	8534 stool	CCFA_RISK
100214.1246953	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127135	23.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100214	100214	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100214	OR100214 stool	CCFA_RISK
SKBTI.1085.1247412	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162312	9.666666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	12/1/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0098	SKBTI.1085	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1085	M1-0098 biopsy	CCFA_RISK
SKBTI.1093.1246216	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162319	10.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	12/13/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0780	SKBTI.1093	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1093	M1-0780 biopsy	CCFA_RISK
SKBTI.0710.1246478	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135628	9.166666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	8/23/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0570	SKBTI.0710	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0710	M1-0570 biopsy	CCFA_RISK
100187.1246918	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127115	15.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100187	100187	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100187	OR100187 stool	CCFA_RISK
SKBTI.0120.1246941	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123042	13.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	11/18/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0221	SKBTI.0120	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0120	M1-0221 biopsy	CCFA_RISK
SKBTI073.1246643	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106944	15.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	6/17/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0170	SKBTI073	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI073	M1-0170 biopsy	CCFA_RISK
MGH104884.1246906	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125746	39.0	no	10/1/69	human	0	9606	MiSeq	human gut metagenome	male	no	12	UBERON:colon	no	15.34	None	biopsy	10/7/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7021	MGH104884	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH104884	7021 biopsy	CCFA_RISK
SKBTI.1337.1246469	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161203	15.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	10/13/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0586	SKBTI.1337	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1337	M1-0586 biopsy	CCFA_RISK
SKBTI.1100.1246300	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161050	10.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:cecum	no	15.34	None	biopsy	7/21/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0742	SKBTI.1100	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1100	M1-0742 biopsy	CCFA_RISK
121959.1246402	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153082	31.0	None	12/4/81	human	0	9606	MiSeq	human gut metagenome	male	no	6	UBERON:feces	no	15.34	None	stool	1/23/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8700	121959	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121959	8700 stool	CCFA_RISK
MGH103728.1247463	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125793	39.0	no	9/9/68	human	0	9606	MiSeq	human gut metagenome	female	no	7	UBERON:ileum	no	15.34	None	biopsy	6/18/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7185	MGH103728	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	yes	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH103728	7185 biopsy	CCFA_RISK
SKBTI.0182.1247424	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123030	13.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	7/6/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0037	SKBTI.0182	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0182	M1-0037 biopsy	CCFA_RISK
SKBTI.0271.1246360	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136015	12.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/4/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0592	SKBTI.0271	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0271	M1-0592 biopsy	CCFA_RISK
SKBTI.0656.1246508	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133791	16.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	7/25/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0705	SKBTI.0656	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0656	M1-0705 biopsy	CCFA_RISK
122010.1247187	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153052	82.0	None	8/14/30	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	12/23/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8683	122010	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	None	no	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	122010	8683 stool	CCFA_RISK
SKBTI.0228.1247018	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155001	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/24/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0303	SKBTI.0228	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0228	M1-0303 biopsy	CCFA_RISK
SKBTI026.1247398	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106897	14.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	8/14/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0061	SKBTI026	408170	BI	.1,g	L2	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI026	M1-0061 biopsy	CCFA_RISK
SKBTI.1276.1246123	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161176	12.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	yes	15.34	None	biopsy	8/18/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0789	SKBTI.1276	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B3	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1276	M1-0789 biopsy	CCFA_RISK
SKBTI.1318.1247045	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161193	7.083333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:cecum	no	15.34	None	biopsy	4/2/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0807	SKBTI.1318	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1318	M1-0807 biopsy	CCFA_RISK
SKBTI.0547.1246855	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133682	12.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/25/11	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0543	SKBTI.0547	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0547	M1-0543 biopsy	CCFA_RISK
SKBTI.0223.1246802	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135926	14.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	yes	15.34	None	biopsy	3/3/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0229	SKBTI.0223	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0223	M1-0229 biopsy	CCFA_RISK
MGH105553.1246787	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125722	52.0	no	3/16/56	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:colon	None	15.34	None	biopsy	1/7/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7365	MGH105553	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	MGH105553	7365 biopsy	CCFA_RISK
SKBTI.0605.1247159	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133740	12.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/27/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0376	SKBTI.0605	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0605	M1-0376 biopsy	CCFA_RISK
SKBTI.0661.1246409	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133796	11.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	8/3/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0468	SKBTI.0661	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0661	M1-0468 biopsy	CCFA_RISK
SKBTI.1121.1246265	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161060	13.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	8/1/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0752	SKBTI.1121	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1121	M1-0752 biopsy	CCFA_RISK
SKBTI.1056.1246237	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162433	7.333333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	9/29/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0261	SKBTI.1056	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1056	M1-0261 biopsy	CCFA_RISK
121953.1246966	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153057	31.0	None	12/4/81	human	0	9606	MiSeq	human gut metagenome	male	no	6	UBERON:feces	no	15.34	None	stool	1/23/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8700	121953	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121953	8700 stool	CCFA_RISK
SKBTI.0721.1246444	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135639	12.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	10/13/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0674	SKBTI.0721	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0721	M1-0674 biopsy	CCFA_RISK
SKBTI.0590.1246908	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133725	14.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	6/27/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0377	SKBTI.0590	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0590	M1-0377 biopsy	CCFA_RISK
SKBTI.1309.1246491	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162471	6.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:colon	no	15.34	None	biopsy	4/24/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0809	SKBTI.1309	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1309	M1-0809 biopsy	CCFA_RISK
SKBTI.1244.1247437	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162391	14.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	3/31/11	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0627	SKBTI.1244	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1244	M1-0627 biopsy	CCFA_RISK
122059.1246857	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153003	29.0	None	10/8/82	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:feces	no	15.34	None	stool	9/26/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8582	122059	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122059	8582 stool	CCFA_RISK
121212.1246767	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136319	27.0	None	8/9/84	human	0	9606	MiSeq	human gut metagenome	female	no	2	UBERON:feces	no	15.34	None	stool	5/16/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8464	121212	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121212	8464 stool	CCFA_RISK
SKBTI082.1246257	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106953	14.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/16/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0243	SKBTI082	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI082	M1-0243 biopsy	CCFA_RISK
SKBTI.0119.1246346	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135955	15.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	11/16/09	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0477	SKBTI.0119	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0119	M1-0477 biopsy	CCFA_RISK
SKBTI.0282.1246147	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155008	12.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/5/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0432	SKBTI.0282	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0282	M1-0432 biopsy	CCFA_RISK
MGH109339.1246622	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125725	37.0	no	12/24/71	human	0	9606	MiSeq	human gut metagenome	female	no	1	UBERON:ileum	no	15.34	None	biopsy	8/12/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7454	MGH109339	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH109339	7454 biopsy	CCFA_RISK
SKBTI.0229.1247019	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123084	12.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/25/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0304	SKBTI.0229	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0229	M1-0304 biopsy	CCFA_RISK
SKBTI.1162.1246549	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161081	9.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:cecum	yes	15.34	None	biopsy	7/26/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0822	SKBTI.1162	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1162	M1-0822 biopsy	CCFA_RISK
SKBTI.0540.1246250	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133675	16.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	5/24/11	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0279	SKBTI.0540	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0540	M1-0279 biopsy	CCFA_RISK
SKBTI.1312.1247312	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162474	7.083333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	None	15.34	None	biopsy	12/8/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0785	SKBTI.1312	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1312	M1-0785 biopsy	CCFA_RISK
SKBTI.0127.1247224	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122979	18.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	10/1/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0297	SKBTI.0127	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0127	M1-0297 biopsy	CCFA_RISK
SKBTI.0665.1246284	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133800	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	8/31/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0258	SKBTI.0665	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0665	M1-0258 biopsy	CCFA_RISK
MGH104690.1247235	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125720	45.0	yes	3/8/63	human	0	9606	MiSeq	human gut metagenome	male	no	34	UBERON:colon	yes	15.34	None	biopsy	9/16/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7003	MGH104690	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	yes	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Transverse colon	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH104690	7003 biopsy	CCFA_RISK
SKBTI.1228.1247034	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161107	9.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	2/20/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0837	SKBTI.1228	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1228	M1-0837 biopsy	CCFA_RISK
SKBTI.0253.1247272	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123108	13.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	3/14/11	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0317	SKBTI.0253	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0253	M1-0317 biopsy	CCFA_RISK
121474.1246486	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136402	34.0	None	8/2/78	human	0	9606	MiSeq	human gut metagenome	female	None	20	UBERON:feces	None	15.34	None	stool	8/14/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8611	121474	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121474	8611 stool	CCFA_RISK
SKBTI.0503.1246992	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133638	15.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/27/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0601	SKBTI.0503	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0503	M1-0601 biopsy	CCFA_RISK
SKBTI.0511.1246178	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133646	13.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	5/2/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0695	SKBTI.0511	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0511	M1-0695 biopsy	CCFA_RISK
SKBTI.0154.1246533	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123005	9.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	7/30/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	east_asian	BI	GAZ:United States of America	None	RISK	1939:M1-0497	SKBTI.0154	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0154	M1-0497 biopsy	CCFA_RISK
SKBTI.1271.1247423	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162453	15.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	None	15.34	None	biopsy	4/29/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0631	SKBTI.1271	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1271	M1-0631 biopsy	CCFA_RISK
SKBTI.1003.1246619	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162417	2.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	3/12/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0776	SKBTI.1003	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.1003	M1-0776 biopsy	CCFA_RISK
SKBTI.1295.1246856	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161184	12.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	yes	15.34	None	biopsy	8/18/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0790	SKBTI.1295	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1295	M1-0790 biopsy	CCFA_RISK
100072.1246982	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125834	18.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100072	100072	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100072	OR100072 stool	CCFA_RISK
122062.1247307	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153020	20.0	None	1/21/92	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:feces	yes	15.34	None	stool	10/22/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8599	122062	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122062	8599 stool	CCFA_RISK
MGH105192.1246837	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125789	33.0	no	5/10/75	human	0	9606	MiSeq	human gut metagenome	male	no	18	UBERON:rectum	yes	15.34	None	biopsy	11/18/08	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7233	MGH105192	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	yes	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH105192	7233 biopsy	CCFA_RISK
SKBTI.0141.1247198	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136008	12.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	8/5/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0440	SKBTI.0141	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0141	M1-0440 biopsy	CCFA_RISK
SKBTI.0881.1246323	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146985	15.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	yes	15.34	None	biopsy	2/3/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0531	SKBTI.0881	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0881	M1-0531 biopsy	CCFA_RISK
SKBTI.0191.1246278	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123039	14.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	7/28/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0522	SKBTI.0191	408170	BI	.1,g	L3	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0191	M1-0522 biopsy	CCFA_RISK
SKBTI.0255.1246590	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123110	13.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/15/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0111	SKBTI.0255	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0255	M1-0111 biopsy	CCFA_RISK
SKBTI.0506.1246925	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133641	15.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/28/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0322	SKBTI.0506	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0506	M1-0322 biopsy	CCFA_RISK
SKBTI.0546.1246182	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133681	6.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	5/23/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0435	SKBTI.0546	408170	BI	.1,g	L1	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0546	M1-0435 biopsy	CCFA_RISK
SKBTI.0529.1246436	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133664	4.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/26/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0106	SKBTI.0529	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0529	M1-0106 biopsy	CCFA_RISK
SKBTI.0111.1247103	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122966	4.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	9/9/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0063	SKBTI.0111	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0111	M1-0063 biopsy	CCFA_RISK
SKBTI.1129.1246576	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161062	16.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	8/8/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0799	SKBTI.1129	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1129	M1-0799 biopsy	CCFA_RISK
SKBTI.1229.1246952	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161108	8.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	2/16/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0745	SKBTI.1229	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1229	M1-0745 biopsy	CCFA_RISK
SKBTI.0868.1246331	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146972	15.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	1/24/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0573	SKBTI.0868	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0868	M1-0573 biopsy	CCFA_RISK
MGH102261.1246301	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125773	24.0	no	3/8/83	human	0	9606	MiSeq	human gut metagenome	female	no	2	UBERON:rectum	no	15.34	None	biopsy	2/26/08	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7125	MGH102261	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	yes	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	yes	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH102261	7125 biopsy	CCFA_RISK
SKBTI.0391.1246196	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-154984	16.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	None	15.34	None	biopsy	10/11/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0391	SKBTI.0391	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0391	M1-0391 biopsy	CCFA_RISK
SKBTI.0754.1246954	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135668	13.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	yes	15.34	None	biopsy	8/24/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0523	SKBTI.0754	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0754	M1-0523 biopsy	CCFA_RISK
SKBTI.1215.1246343	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162374	12.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	11/22/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0765	SKBTI.1215	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1215	M1-0765 biopsy	CCFA_RISK
SKBTI.0703.1246441	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155038	13.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	yes	15.34	None	biopsy	9/19/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0289	SKBTI.0703	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0703	M1-0289 biopsy	CCFA_RISK
SKBTI.0928.1246940	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147032	10.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	6/25/12	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	east_asian	BI	GAZ:United States of America	None	RISK	1939:M1-0712	SKBTI.0928	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0928	M1-0712 biopsy	CCFA_RISK
SKBTI.0731.1247425	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-154974	12.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	11/1/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0617	SKBTI.0731	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0731	M1-0617 biopsy	CCFA_RISK
100188.1247093	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127116	53.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100188	100188	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100188	OR100188 stool	CCFA_RISK
SKBTI.0265.1247058	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136007	5.416666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	1/15/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0680	SKBTI.0265	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0265	M1-0680 biopsy	CCFA_RISK
SKBTI038.1246928	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106909	16.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	11/10/08	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0196	SKBTI038	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI038	M1-0196 biopsy	CCFA_RISK
SKBTI.1002.1246244	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162416	9.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	3/15/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0413	SKBTI.1002	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1002	M1-0413 biopsy	CCFA_RISK
SKBTI.0114.1247070	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122969	7.166666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	10/5/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0216	SKBTI.0114	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0114	M1-0216 biopsy	CCFA_RISK
122038.1247249	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153038	21.0	None	8/2/91	human	0	9606	MiSeq	human gut metagenome	female	yes	1	UBERON:feces	yes	15.34	None	stool	12/4/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8649	122038	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122038	8649 stool	CCFA_RISK
SKBTI.0593.1247128	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133728	12.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	6/28/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0595	SKBTI.0593	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0593	M1-0595 biopsy	CCFA_RISK
SKBTI.0172.1246154	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135950	12.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	5/18/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	arab	BI	GAZ:United States of America	None	RISK	1939:M1-0239	SKBTI.0172	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0172	M1-0239 biopsy	CCFA_RISK
SKBTI.0116.1247470	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122970	12.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	yes	15.34	None	biopsy	11/9/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0220	SKBTI.0116	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0116	M1-0220 biopsy	CCFA_RISK
121189.1247011	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136306	37.0	None	10/10/74	human	0	9606	MiSeq	human gut metagenome	female	None	8	UBERON:feces	None	15.34	None	stool	4/19/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8469	121189	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	121189	8469 stool	CCFA_RISK
121312.1246929	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136340	43.0	None	6/21/69	human	0	9606	MiSeq	human gut metagenome	female	no	20	UBERON:feces	yes	15.34	None	stool	6/27/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Current	PRISM	1939:8569	121312	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121312	8569 stool	CCFA_RISK
MGH100601.1247258	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136047	27.0	yes	9/9/79	human	0	9606	MiSeq	human gut metagenome	female	no	6	UBERON:colon	no	15.34	None	biopsy	8/1/07	0.0	yes	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7111	MGH100601	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	yes	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH100601	7111 biopsy	CCFA_RISK
SKBTI.0209.1247324	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-154998	13.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	1/29/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0070	SKBTI.0209	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0209	M1-0070 biopsy	CCFA_RISK
SKBTI.0563.1246778	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133698	16.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	6/13/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0669	SKBTI.0563	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0563	M1-0669 biopsy	CCFA_RISK
SKBTI.0690.1246273	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135610	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	yes	15.34	None	biopsy	12/15/11	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0292	SKBTI.0690	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0690	M1-0292 biopsy	CCFA_RISK
SKBTI.1089.1246274	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162316	16.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	12/6/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0839	SKBTI.1089	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1089	M1-0839 biopsy	CCFA_RISK
SKBTI.1152.1247201	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162439	9.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:colon	no	15.34	None	biopsy	7/27/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0760	SKBTI.1152	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1152	M1-0760 biopsy	CCFA_RISK
SKBTI.0622.1247025	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133757	8.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/15/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0191	SKBTI.0622	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0622	M1-0191 biopsy	CCFA_RISK
SKBTI016.1246701	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106887	13.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	11/5/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0027	SKBTI016	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI016	M1-0027 biopsy	CCFA_RISK
121218.1246965	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136325	30.0	None	10/6/81	human	0	9606	MiSeq	human gut metagenome	male	no	15	UBERON:feces	no	15.34	None	stool	6/25/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8564	121218	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121218	8564 stool	CCFA_RISK
SKBTI.1175.1246501	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161088	10.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	yes	15.34	None	biopsy	6/21/10	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0796	SKBTI.1175	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1175	M1-0796 biopsy	CCFA_RISK
SKBTI.0236.1246777	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123091	14.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	3/1/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0314	SKBTI.0236	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0236	M1-0314 biopsy	CCFA_RISK
SKBTI.1111.1246524	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162329	9.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	7/25/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0704	SKBTI.1111	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1111	M1-0704 biopsy	CCFA_RISK
121466.1247362	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136290	60.0	None	8/12/49	human	0	9606	MiSeq	human gut metagenome	female	no	40	UBERON:feces	no	15.34	None	stool	5/11/10	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:7948	121466	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121466	7948 stool	CCFA_RISK
122115.1246871	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153089	30.0	None	10/13/82	human	0	9606	MiSeq	human gut metagenome	female	no	11	UBERON:feces	no	15.34	None	stool	3/1/13	0.0	None	ENVO:urban biome	None	Illumina	None	other	BI	GAZ:United States of America	Never	PRISM	1939:8726	122115	408170	BI	.1,g	J-Pouch	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B2	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122115	8726 stool	CCFA_RISK
121470.1246944	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136370	28.0	None	1/24/83	human	0	9606	MiSeq	human gut metagenome	female	no	16	UBERON:feces	no	15.34	None	stool	5/5/11	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:7486	121470	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121470	7486 stool	CCFA_RISK
SKBTI.0953.1247267	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147057	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	2/25/11	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	other	BI	GAZ:United States of America	None	RISK	1939:M1-0580	SKBTI.0953	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0953	M1-0580 biopsy	CCFA_RISK
SKBTI.0256.1246186	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136009	9.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	None	15.34	None	biopsy	3/15/11	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0578	SKBTI.0256	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0256	M1-0578 biopsy	CCFA_RISK
SKBTI011.1246249	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106882	9.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/27/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0206	SKBTI011	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI011	M1-0206 biopsy	CCFA_RISK
SKBTI.0979.1247383	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161116	12.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:cecum	no	15.34	None	biopsy	2/8/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0354	SKBTI.0979	408170	BI	.1,g	L1	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0979	M1-0354 biopsy	CCFA_RISK
SKBTI.1185.1247366	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162357	14.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	2/25/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0834	SKBTI.1185	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1185	M1-0834 biopsy	CCFA_RISK
SKBTI.0253.1246145	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155003	13.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	3/14/11	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0317	SKBTI.0253	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0253	M1-0317 biopsy	CCFA_RISK
SKBTI.0193.1246598	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123051	13.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	8/2/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0561	SKBTI.0193	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0193	M1-0561 biopsy	CCFA_RISK
122032.1246450	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153017	38.0	None	5/31/74	human	0	9606	MiSeq	human gut metagenome	male	no	1	UBERON:feces	yes	15.34	None	stool	2/27/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8585	122032	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122032	8585 stool	CCFA_RISK
100015.1247049	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125818	57.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100015	100015	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100015	OR100015 stool	CCFA_RISK
SKBTI.0970.1246745	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162400	11.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:cecum	no	15.34	None	biopsy	11/4/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0026	SKBTI.0970	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0970	M1-0026 biopsy	CCFA_RISK
SKBTI.0497.1247380	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133632	14.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	yes	15.34	None	biopsy	4/19/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0459	SKBTI.0497	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0497	M1-0459 biopsy	CCFA_RISK
SKBTI.0640.1246181	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133775	10.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/13/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0549	SKBTI.0640	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0640	M1-0549 biopsy	CCFA_RISK
SKBTI.0932.1246975	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147036	16.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/8/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0493	SKBTI.0932	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0932	M1-0493 biopsy	CCFA_RISK
SKBTI.1140.1246476	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162340	16.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	8/11/11	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0800	SKBTI.1140	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1140	M1-0800 biopsy	CCFA_RISK
SKBTI.0929.1246260	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147033	8.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	yes	15.34	None	biopsy	4/6/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0235	SKBTI.0929	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0929	M1-0235 biopsy	CCFA_RISK
SKBTI.1310.1247461	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162472	6.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	4/24/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0809	SKBTI.1310	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1310	M1-0809 biopsy	CCFA_RISK
MGH129951.1247358	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136068	66.0	no	9/23/45	human	0	9606	MiSeq	human gut metagenome	male	no	1	UBERON:colon	no	15.34	None	biopsy	5/15/12	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:8520	MGH129951	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Transverse colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH129951	8520 biopsy	CCFA_RISK
SKBTI.0190.1246201	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123038	11.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/22/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0479	SKBTI.0190	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0190	M1-0479 biopsy	CCFA_RISK
SKBTI.0603.1246269	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133738	5.416666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/2/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0151	SKBTI.0603	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0603	M1-0151 biopsy	CCFA_RISK
100181.1246841	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127111	67.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100181	100181	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100181	OR100181 stool	CCFA_RISK
SKBTI.0168.1246827	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123018	16.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/8/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0493	SKBTI.0168	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0168	M1-0493 biopsy	CCFA_RISK
SKBTI.1302.1246218	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161188	9.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	5/10/12	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0770	SKBTI.1302	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1302	M1-0770 biopsy	CCFA_RISK
121953.1247287	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153083	31.0	None	12/4/81	human	0	9606	MiSeq	human gut metagenome	male	no	6	UBERON:feces	no	15.34	None	stool	1/23/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8700	121953	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121953	8700 stool	CCFA_RISK
SKBTI.0132.1247149	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122984	11.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	yes	15.34	None	biopsy	8/16/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0256	SKBTI.0132	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0132	M1-0256 biopsy	CCFA_RISK
MGH100826.1246528	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125776	48.0	no	1/15/59	human	0	9606	MiSeq	human gut metagenome	female	no	20	UBERON:colon	no	15.34	None	biopsy	9/4/07	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7130	MGH100826	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Ascending colon	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH100826	7130 biopsy	CCFA_RISK
SKBTI.0587.1246373	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133722	15.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/20/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0701	SKBTI.0587	408170	BI	.1,g	L3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0587	M1-0701 biopsy	CCFA_RISK
SKBTI.0890.1246256	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146994	13.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	5/25/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0374	SKBTI.0890	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0890	M1-0374 biopsy	CCFA_RISK
SKBTI.0731.1246888	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135606	12.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	11/1/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0617	SKBTI.0731	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0731	M1-0617 biopsy	CCFA_RISK
SKBTI.1145.1246684	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161073	13.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	8/10/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0286	SKBTI.1145	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1145	M1-0286 biopsy	CCFA_RISK
SKBTI.0184.1247369	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123032	9.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	7/13/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0619	SKBTI.0184	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0184	M1-0619 biopsy	CCFA_RISK
SKBTI.0213.1246384	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123069	13.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	2/9/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0302	SKBTI.0213	408170	BI	.1,g	L2	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0213	M1-0302 biopsy	CCFA_RISK
SKBTI.1237.1246429	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162386	14.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	12/17/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0678	SKBTI.1237	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1237	M1-0678 biopsy	CCFA_RISK
SKBTI.0122.1246970	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122975	12.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	12/11/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	yes	african	BI	GAZ:United States of America	None	RISK	1939:M1-0029	SKBTI.0122	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0122	M1-0029 biopsy	CCFA_RISK
MGH104623.1246457	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125887	36.0	no	9/20/71	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:cecum	no	15.34	None	biopsy	9/3/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7347	MGH104623	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH104623	7347 biopsy	CCFA_RISK
121213.1246142	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136320	36.0	None	2/26/76	human	0	9606	MiSeq	human gut metagenome	female	no	6	UBERON:feces	no	15.34	None	stool	6/11/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8471	121213	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121213	8471 stool	CCFA_RISK
SKBTI.0224.1246955	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123079	14.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/4/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0230	SKBTI.0224	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0224	M1-0230 biopsy	CCFA_RISK
MGH102719.1247439	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125749	32.0	yes	6/18/75	human	0	9606	MiSeq	human gut metagenome	female	no	5	UBERON:colon	no	15.34	None	biopsy	3/18/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7037	MGH102719	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH102719	7037 biopsy	CCFA_RISK
122010.1246652	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153078	82.0	None	8/14/30	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	12/23/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8683	122010	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	None	no	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	122010	8683 stool	CCFA_RISK
SKBTI.0585.1246750	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133720	16.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/21/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0622	SKBTI.0585	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0585	M1-0622 biopsy	CCFA_RISK
SKBTI.0176.1246981	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123026	15.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/27/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0308	SKBTI.0176	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0176	M1-0308 biopsy	CCFA_RISK
121421.1246406	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136358	58.0	None	4/6/52	human	0	9606	MiSeq	human gut metagenome	female	no	16	UBERON:feces	no	15.34	None	stool	6/16/10	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:7947	121421	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B2	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121421	7947 stool	CCFA_RISK
SKBTI.0235.1246605	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123090	11.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/1/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0313	SKBTI.0235	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0235	M1-0313 biopsy	CCFA_RISK
SKBTI.0620.1246529	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133755	16.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/6/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0644	SKBTI.0620	408170	BI	.1,g	L3	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0620	M1-0644 biopsy	CCFA_RISK
MGH105658.1247134	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125790	36.0	no	5/1/72	human	0	9606	MiSeq	human gut metagenome	female	no	9	UBERON:colon	no	15.34	None	biopsy	1/21/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7221	MGH105658	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	yes	CD	UBERON:gastrointestinal system	sequencing by synthesis	B3	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH105658	7221 biopsy	CCFA_RISK
100204.1247092	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127127	18.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100204	100204	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100204	OR100204 stool	CCFA_RISK
SKBTI.1239.1246712	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161111	16.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	4/11/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0750	SKBTI.1239	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1239	M1-0750 biopsy	CCFA_RISK
SKBTI.0733.1246582	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135650	12.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	11/15/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0291	SKBTI.0733	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0733	M1-0291 biopsy	CCFA_RISK
121488.1246443	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136411	36.0	None	10/27/75	human	0	9606	MiSeq	human gut metagenome	female	no	9	UBERON:feces	no	15.34	None	stool	10/16/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8642	121488	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121488	8642 stool	CCFA_RISK
SKBTI.0619.1247073	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133754	9.083333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	None	15.34	None	biopsy	7/8/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0640	SKBTI.0619	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0619	M1-0640 biopsy	CCFA_RISK
MGH101249.1246536	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125873	37.0	yes	11/8/69	human	0	9606	MiSeq	human gut metagenome	male	no	10	UBERON:colon	no	15.34	None	biopsy	10/16/07	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7077	MGH101249	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Ascending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH101249	7077 biopsy	CCFA_RISK
121182.1246215	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136299	26.0	None	3/26/85	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:feces	no	15.34	None	stool	3/9/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8467	121182	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121182	8467 stool	CCFA_RISK
SKBTI.0251.1247301	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123106	13.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/10/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0187	SKBTI.0251	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0251	M1-0187 biopsy	CCFA_RISK
SKBTI.1291.1247334	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162461	15.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	8/26/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0756	SKBTI.1291	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1291	M1-0756 biopsy	CCFA_RISK
SKBTI.1120.1246645	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162331	10.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	None	15.34	None	biopsy	8/1/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0673	SKBTI.1120	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1120	M1-0673 biopsy	CCFA_RISK
SKBTI040.1246439	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106911	12.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	2/25/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0014	SKBTI040	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI040	M1-0014 biopsy	CCFA_RISK
122075.1246458	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153012	30.0	None	10/8/82	human	0	9606	MiSeq	human gut metagenome	female	no	1	UBERON:feces	no	15.34	None	stool	3/5/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8582	122075	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122075	8582 stool	CCFA_RISK
SKBTI.1268.1246698	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162450	15.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	4/28/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0322	SKBTI.1268	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1268	M1-0322 biopsy	CCFA_RISK
SKBTI.0496.1246204	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133631	12.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/18/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0691	SKBTI.0496	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0496	M1-0691 biopsy	CCFA_RISK
121403.1247087	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136354	49.0	None	3/28/63	human	0	9606	MiSeq	human gut metagenome	male	no	5	UBERON:feces	no	15.34	None	stool	9/28/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8558	121403	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121403	8558 stool	CCFA_RISK
SKBTI.1118.1247169	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162330	14.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	10/24/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0732	SKBTI.1118	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1118	M1-0732 biopsy	CCFA_RISK
100161.1246172	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125866	53.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100161	100161	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100161	OR100161 stool	CCFA_RISK
SKBTI.0768.1246711	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135681	9.166666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	None	15.34	None	biopsy	12/21/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0380	SKBTI.0768	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0768	M1-0380 biopsy	CCFA_RISK
SKBTI066.1247046	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127158	10.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	10/15/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0177	SKBTI066	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI066	M1-0177 biopsy	CCFA_RISK
SKBTI.0157.1246707	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135947	15.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/15/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0306	SKBTI.0157	408170	BI	.1,g	L3	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0157	M1-0306 biopsy	CCFA_RISK
SKBTI.1241.1247284	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162388	16.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/11/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0725	SKBTI.1241	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1241	M1-0725 biopsy	CCFA_RISK
121190.1246356	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136307	65.0	None	9/14/46	human	0	9606	MiSeq	human gut metagenome	male	no	39	UBERON:feces	yes	15.34	None	stool	3/19/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8475	121190	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B2	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121190	8475 stool	CCFA_RISK
SKBTI.0254.1246845	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123109	16.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	3/15/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0114	SKBTI.0254	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0254	M1-0114 biopsy	CCFA_RISK
SKBTI.1180.1246130	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162353	15.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	2/23/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0683	SKBTI.1180	408170	BI	.1,g	L3	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1180	M1-0683 biopsy	CCFA_RISK
MGH100525.1247317	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125744	36.0	no	5/10/71	human	0	9606	MiSeq	human gut metagenome	male	no	9	UBERON:colon	no	15.34	None	biopsy	8/8/07	0.0	yes	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7016	MGH100525	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	yes	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH100525	7016 biopsy	CCFA_RISK
SKBTI.1208.1247059	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161096	9.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:cecum	no	15.34	None	biopsy	2/14/12	0.0	no	ENVO:urban biome	None	Illumina	yes	other	BI	GAZ:United States of America	None	RISK	1939:M1-0195	SKBTI.1208	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1208	M1-0195 biopsy	CCFA_RISK
MGH109812.1246153	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125732	27.0	no	3/2/82	human	0	9606	MiSeq	human gut metagenome	male	no	4	UBERON:ileum	no	15.34	None	biopsy	9/2/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7624	MGH109812	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B3	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH109812	7624 biopsy	CCFA_RISK
SKBTI072.1246897	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106943	15.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/29/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0021	SKBTI072	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI072	M1-0021 biopsy	CCFA_RISK
100210.1247298	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127132	61.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	2	OSCCAR	1939:OR100210	100210	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100210	OR100210 stool	CCFA_RISK
SKBTI.0523.1246271	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133658	15.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/28/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0080	SKBTI.0523	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0523	M1-0080 biopsy	CCFA_RISK
100052.1246453	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125826	23.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100052	100052	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100052	OR100052 stool	CCFA_RISK
SKBTI.1115.1247450	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161056	9.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:cecum	yes	15.34	None	biopsy	7/26/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0822	SKBTI.1115	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1115	M1-0822 biopsy	CCFA_RISK
SKBTI.1066.1246699	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161033	15.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:colon	no	15.34	None	biopsy	9/21/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0500	SKBTI.1066	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Transverse colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1066	M1-0500 biopsy	CCFA_RISK
121456.1246221	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136280	31.0	None	3/2/79	human	0	9606	MiSeq	human gut metagenome	female	no	5	UBERON:feces	no	15.34	None	stool	9/21/10	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:7962	121456	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121456	7962 stool	CCFA_RISK
SKBTI.0143.1247308	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135945	11.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	8/16/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0498	SKBTI.0143	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0143	M1-0498 biopsy	CCFA_RISK
SKBTI.1046.1246367	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161161	5.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	9/16/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0588	SKBTI.1046	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1046	M1-0588 biopsy	CCFA_RISK
SKBTI.1294.1246815	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162464	13.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	8/26/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0744	SKBTI.1294	408170	BI	.1,g	L1	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1294	M1-0744 biopsy	CCFA_RISK
MGH102504.1247273	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125778	35.0	no	3/20/72	human	0	9606	MiSeq	human gut metagenome	male	no	25	UBERON:colon	yes	15.34	None	biopsy	3/10/08	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7135	MGH102504	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B3	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH102504	7135 biopsy	CCFA_RISK
SKBTI.0630.1246580	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133765	3.166666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	6/10/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0035	SKBTI.0630	408170	BI	.1,g	L1	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0630	M1-0035 biopsy	CCFA_RISK
SKBTI.0755.1246781	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135669	10.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	8/3/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0562	SKBTI.0755	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0755	M1-0562 biopsy	CCFA_RISK
SKBTI.1344.1246299	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162488	16.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	10/18/11	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0791	SKBTI.1344	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1344	M1-0791 biopsy	CCFA_RISK
MGH102701.1246596	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125785	46.0	no	3/12/62	human	0	9606	MiSeq	human gut metagenome	female	no	30	UBERON:ileum	yes	15.34	None	biopsy	3/18/08	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	None	PRISM	1939:7164	MGH102701	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B3	yes	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH102701	7164 biopsy	CCFA_RISK
SKBTI.1063.1246477	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161030	15.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:colon	no	15.34	None	biopsy	9/21/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0500	SKBTI.1063	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1063	M1-0500 biopsy	CCFA_RISK
SKBTI.1210.1246931	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161098	16.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	4/29/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0694	SKBTI.1210	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1210	M1-0694 biopsy	CCFA_RISK
SKBTI.1320.1246552	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161194	1.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	4/27/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0153	SKBTI.1320	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1320	M1-0153 biopsy	CCFA_RISK
SKBTI.0098.1247278	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122953	15.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	2/11/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0346	SKBTI.0098	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0098	M1-0346 biopsy	CCFA_RISK
SKBTI085.1247253	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106956	9.333333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	12/3/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0183	SKBTI085	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI085	M1-0183 biopsy	CCFA_RISK
SKBTI015.1247138	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106886	10.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/8/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0231	SKBTI015	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI015	M1-0231 biopsy	CCFA_RISK
100158.1246456	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125864	47.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100158	100158	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100158	OR100158 stool	CCFA_RISK
SKBTI.0153.1247415	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123004	6.083333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	10/1/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0553	SKBTI.0153	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0153	M1-0553 biopsy	CCFA_RISK
SKBTI.1031.1247110	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161150	10.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	11/3/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0092	SKBTI.1031	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1031	M1-0092 biopsy	CCFA_RISK
SKBTI.1011.1247377	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161133	16.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:cecum	no	15.34	None	biopsy	5/10/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0747	SKBTI.1011	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1011	M1-0747 biopsy	CCFA_RISK
SKBTI.1174.1246939	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161087	10.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	8/17/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0838	SKBTI.1174	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1174	M1-0838 biopsy	CCFA_RISK
SKBTI.0525.1246911	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155027	10.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/28/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0365	SKBTI.0525	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0525	M1-0365 biopsy	CCFA_RISK
SKBTI.1030.1246748	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161149	10.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	11/5/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0094	SKBTI.1030	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1030	M1-0094 biopsy	CCFA_RISK
100190.1246494	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127117	9.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100190	100190	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100190	OR100190 stool	CCFA_RISK
SKBTI.0110.1247026	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122965	9.166666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/21/09	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0020	SKBTI.0110	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0110	M1-0020 biopsy	CCFA_RISK
SKBTI.1342.1246211	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162486	16.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	10/17/11	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0757	SKBTI.1342	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1342	M1-0757 biopsy	CCFA_RISK
100089.1247168	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125846	22.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100089	100089	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100089	OR100089 stool	CCFA_RISK
MGH104945.1247409	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125777	47.0	no	8/12/61	human	0	9606	MiSeq	human gut metagenome	male	no	20	UBERON:cecum	no	15.34	None	biopsy	10/14/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7134	MGH104945	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH104945	7134 biopsy	CCFA_RISK
SKBTI.1262.1247411	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161174	12.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/27/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0836	SKBTI.1262	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1262	M1-0836 biopsy	CCFA_RISK
SKBTI.1293.1246451	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162463	13.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	8/26/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0744	SKBTI.1293	408170	BI	.1,g	L1	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1293	M1-0744 biopsy	CCFA_RISK
SKBTI.0212.1247473	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123068	14.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	2/1/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0353	SKBTI.0212	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0212	M1-0353 biopsy	CCFA_RISK
SKBTI.0232.1247457	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123087	8.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	yes	15.34	None	biopsy	4/6/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0235	SKBTI.0232	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0232	M1-0235 biopsy	CCFA_RISK
SKBTI.0275.1246424	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123129	14.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/31/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0627	SKBTI.0275	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0275	M1-0627 biopsy	CCFA_RISK
100207.1247256	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127130	15.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100207	100207	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100207	OR100207 stool	CCFA_RISK
121465.1246414	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136289	46.0	None	9/19/63	human	0	9606	MiSeq	human gut metagenome	female	None	3	UBERON:feces	None	15.34	None	stool	4/21/10	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:7943	121465	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	121465	7943 stool	CCFA_RISK
MGH105693.1246732	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125879	38.0	yes	12/18/70	human	0	9606	MiSeq	human gut metagenome	female	no	9	UBERON:ileum	no	15.34	None	biopsy	1/29/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7175	MGH105693	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	yes	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH105693	7175 biopsy	CCFA_RISK
121468.1247263	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153004	30.0	None	10/8/82	human	0	9606	MiSeq	human gut metagenome	female	no	1	UBERON:feces	no	15.34	None	stool	10/26/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8582	121468	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121468	8582 stool	CCFA_RISK
SKBTI.0216.1246266	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123072	9.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	2/10/10	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0356	SKBTI.0216	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0216	M1-0356 biopsy	CCFA_RISK
SKBTI.0943.1246435	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147047	7.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	4/11/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0372	SKBTI.0943	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0943	M1-0372 biopsy	CCFA_RISK
SKBTI.0522.1247183	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133701	15.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/23/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0078	SKBTI.0522	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0522	M1-0078 biopsy	CCFA_RISK
SKBTI.1236.1246678	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162385	14.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/12/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0457	SKBTI.1236	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1236	M1-0457 biopsy	CCFA_RISK
100107.1246180	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125859	12.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100107	100107	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100107	OR100107 stool	CCFA_RISK
SKBTI.0967.1247125	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162397	12.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:cecum	no	15.34	None	biopsy	10/27/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0218	SKBTI.0967	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0967	M1-0218 biopsy	CCFA_RISK
121968.1246353	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153080	31.0	None	12/4/81	human	0	9606	MiSeq	human gut metagenome	male	no	6	UBERON:feces	no	15.34	None	stool	1/23/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8700	121968	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121968	8700 stool	CCFA_RISK
SKBTI043.1246333	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106914	14.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	1/14/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0164	SKBTI043	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI043	M1-0164 biopsy	CCFA_RISK
MGH105361.1246445	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125762	38.0	no	8/8/70	human	0	9606	MiSeq	human gut metagenome	female	no	19	UBERON:ileum	no	15.34	None	biopsy	11/25/08	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7284	MGH105361	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	yes	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH105361	7284 biopsy	CCFA_RISK
MGH100698.1246875	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125791	75.0	no	4/3/32	human	0	9606	MiSeq	human gut metagenome	female	no	14	UBERON:ileum	no	15.34	None	biopsy	8/21/07	0.0	yes	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7225	MGH100698	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH100698	7225 biopsy	CCFA_RISK
SKBTI.0151.1247294	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123003	14.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	10/27/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0597	SKBTI.0151	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0151	M1-0597 biopsy	CCFA_RISK
SKBTI.0515.1246849	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133650	15.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/5/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0126	SKBTI.0515	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0515	M1-0126 biopsy	CCFA_RISK
SKBTI083.1246839	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106954	10.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/16/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0036	SKBTI083	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI083	M1-0036 biopsy	CCFA_RISK
SKBTI.0505.1246761	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133640	12.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/26/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0269	SKBTI.0505	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0505	M1-0269 biopsy	CCFA_RISK
100100.1246674	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125853	53.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100100	100100	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	yes	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100100	OR100100 stool	CCFA_RISK
122099.1246768	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153061	30.0	None	10/13/82	human	0	9606	MiSeq	human gut metagenome	female	no	11	UBERON:feces	no	15.34	None	stool	3/1/13	0.0	None	ENVO:urban biome	None	Illumina	None	other	BI	GAZ:United States of America	Never	PRISM	1939:8726	122099	408170	BI	.1,g	J-Pouch	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B2	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122099	8726 stool	CCFA_RISK
SKBTI058.1246566	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106929	11.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	9/9/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0062	SKBTI058	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI058	M1-0062 biopsy	CCFA_RISK
SKBTI.1081.1246410	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161044	15.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	11/22/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0749	SKBTI.1081	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1081	M1-0749 biopsy	CCFA_RISK
SKBTI.0363.1247102	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29E7.1.Solexa-124724	16.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	12/21/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0268	SKBTI.0363	408170	BI	.1,g	L2	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0363	M1-0268 biopsy	CCFA_RISK
121201.1247061	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136318	30.0	None	6/10/82	human	0	9606	MiSeq	human gut metagenome	female	no	6	UBERON:feces	no	15.34	None	stool	6/12/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8550	121201	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121201	8550 stool	CCFA_RISK
SKBTI.0756.1246400	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135602	12.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/27/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0579	SKBTI.0756	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0756	M1-0579 biopsy	CCFA_RISK
SKBTI.0519.1246686	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133654	12.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	5/10/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0486	SKBTI.0519	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0519	M1-0486 biopsy	CCFA_RISK
121980.1246352	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153059	48.0	None	1/8/65	human	0	9606	MiSeq	human gut metagenome	female	no	1	UBERON:feces	no	15.34	None	stool	2/13/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8712	121980	408170	BI	.1,g	E1	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121980	8712 stool	CCFA_RISK
SKBTI.1313.1246920	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162475	7.083333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	None	15.34	None	biopsy	12/8/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0785	SKBTI.1313	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1313	M1-0785 biopsy	CCFA_RISK
SKBTI.1206.1246813	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161094	3.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	2/8/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0108	SKBTI.1206	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1206	M1-0108 biopsy	CCFA_RISK
122034.1246359	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153050	21.0	None	2/14/91	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:feces	no	15.34	None	stool	1/14/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Current	PRISM	1939:8678	122034	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	122034	8678 stool	CCFA_RISK
SKBTI.0617.1246816	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133752	13.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/8/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0512	SKBTI.0617	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0617	M1-0512 biopsy	CCFA_RISK
SKBTI.0504.1246609	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133700	6.333333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/27/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0461	SKBTI.0504	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0504	M1-0461 biopsy	CCFA_RISK
SKBTI.1058.1246865	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161027	15.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	10/19/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0262	SKBTI.1058	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1058	M1-0262 biopsy	CCFA_RISK
SKBTI.1182.1247072	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162354	6.666666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	2/24/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0626	SKBTI.1182	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1182	M1-0626 biopsy	CCFA_RISK
SKBTI.0204.1247440	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-154997	15.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	1/12/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0478	SKBTI.0204	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0204	M1-0478 biopsy	CCFA_RISK
SKBTI056.1246357	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106927	16.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	7/2/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0171	SKBTI056	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI056	M1-0171 biopsy	CCFA_RISK
MGH101089.1246332	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125741	32.0	no	2/2/75	human	0	9606	MiSeq	human gut metagenome	female	no	1	UBERON:ileum	no	15.34	None	biopsy	9/26/07	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7251	MGH101089	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH101089	7251 biopsy	CCFA_RISK
121477.1246644	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136405	36.0	None	5/27/74	human	0	9606	MiSeq	human gut metagenome	female	no	12	UBERON:feces	yes	15.34	None	stool	6/21/10	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:7989	121477	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121477	7989 stool	CCFA_RISK
121187.1246148	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136304	25.0	None	7/9/86	human	0	9606	MiSeq	human gut metagenome	male	no	19	UBERON:feces	no	15.34	None	stool	2/29/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8452	121187	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121187	8452 stool	CCFA_RISK
SKBTI.0207.1246564	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123063	12.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/27/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0223	SKBTI.0207	408170	BI	.1,g	L2	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0207	M1-0223 biopsy	CCFA_RISK
120155.1246996	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136294	29.0	None	3/3/80	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	3/1/10	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	None	PRISM	1939:7879	120155	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	None	no	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	121155	7879 stool	CCFA_RISK
SKBTI.0934.1246826	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147038	12.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	5/18/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	arab	BI	GAZ:United States of America	None	RISK	1939:M1-0239	SKBTI.0934	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0934	M1-0239 biopsy	CCFA_RISK
SKBTI.0146.1247223	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122998	13.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	yes	15.34	None	biopsy	6/11/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	east_asian	BI	GAZ:United States of America	None	RISK	1939:M1-0386	SKBTI.0146	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0146	M1-0386 biopsy	CCFA_RISK
SKBTI.0704.1246421	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135608	7.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	9/13/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0471	SKBTI.0704	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0704	M1-0471 biopsy	CCFA_RISK
SKBTI.0734.1246141	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135651	8.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	11/10/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0341	SKBTI.0734	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0734	M1-0341 biopsy	CCFA_RISK
SKBTI.0573.1246286	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133803	16.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/17/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0635	SKBTI.0573	408170	BI	.1,g	L3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0573	M1-0635 biopsy	CCFA_RISK
SKBTI.0885.1246629	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146989	11.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	3/1/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0313	SKBTI.0885	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0885	M1-0313 biopsy	CCFA_RISK
100220.1247083	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127139	27.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100220	100220	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100220	OR100220 stool	CCFA_RISK
SKBTI.0268.1247386	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123123	12.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/23/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0116	SKBTI.0268	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0268	M1-0116 biopsy	CCFA_RISK
SKBTI.1028.1246874	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161147	10.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	11/3/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0093	SKBTI.1028	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1028	M1-0093 biopsy	CCFA_RISK
SKBTI.0242.1246464	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123097	11.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/7/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0401	SKBTI.0242	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0242	M1-0401 biopsy	CCFA_RISK
SKBTI.0942.1246434	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147046	5.416666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	5/23/12	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0158	SKBTI.0942	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0942	M1-0158 biopsy	CCFA_RISK
100080.1246540	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125840	74.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100080	100080	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100080	OR100080 stool	CCFA_RISK
121471.1246191	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136425	28.0	None	5/11/82	human	0	9606	MiSeq	human gut metagenome	male	no	17	UBERON:feces	no	15.34	None	stool	5/5/11	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:7759	121471	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121471	7759 stool	CCFA_RISK
SKBTI.0113.1246743	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122968	12.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	yes	15.34	None	biopsy	5/18/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0520	SKBTI.0113	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0113	M1-0520 biopsy	CCFA_RISK
SKBTI042.1247009	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106913	13.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	7/30/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0211	SKBTI042	408170	BI	.1,g	L2	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI042	M1-0211 biopsy	CCFA_RISK
SKBTI.1108.1246648	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162327	9.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:colon	no	15.34	None	biopsy	7/27/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0760	SKBTI.1108	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1108	M1-0760 biopsy	CCFA_RISK
SKBTI.0211.1246916	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123067	15.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	2/1/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0301	SKBTI.0211	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0211	M1-0301 biopsy	CCFA_RISK
SKBTI.1018.1246280	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162422	16.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	6/14/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0077	SKBTI.1018	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1018	M1-0077 biopsy	CCFA_RISK
SKBTI.0866.1247116	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146970	12.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	12/15/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0566	SKBTI.0866	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0866	M1-0566 biopsy	CCFA_RISK
SKBTI.0274.1247097	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135927	12.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/30/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0118	SKBTI.0274	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0274	M1-0118 biopsy	CCFA_RISK
SKBTI.0205.1247390	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123061	13.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/18/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0298	SKBTI.0205	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0205	M1-0298 biopsy	CCFA_RISK
SKBTI.1346.1247074	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161018	9.666666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	yes	15.34	None	biopsy	10/24/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0731	SKBTI.1346	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1346	M1-0731 biopsy	CCFA_RISK
121404.1246695	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136355	44.0	None	4/15/68	human	0	9606	MiSeq	human gut metagenome	female	no	4	UBERON:feces	no	15.34	None	stool	9/12/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8575	121404	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121404	8575 stool	CCFA_RISK
SKBTI.1130.1246867	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161063	16.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	8/10/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0782	SKBTI.1130	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1130	M1-0782 biopsy	CCFA_RISK
100182.1247008	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127112	69.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100182	100182	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	yes	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100182	OR100182 stool	CCFA_RISK
SKBTI.1024.1246425	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161143	9.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:colon	no	15.34	None	biopsy	7/13/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0619	SKBTI.1024	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Ascending colon	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1024	M1-0619 biopsy	CCFA_RISK
SKBTI.0301.1246255	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29E7.1.Solexa-124664	12.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	2/8/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0430	SKBTI.0301	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0301	M1-0430 biopsy	CCFA_RISK
SKBTI.1336.1246442	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161202	12.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	10/13/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0674	SKBTI.1336	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1336	M1-0674 biopsy	CCFA_RISK
122163.1246523	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153075	21.0	None	2/14/91	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:feces	no	15.34	None	stool	12/17/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Current	PRISM	1939:8678	122163	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	122163	8678 stool	CCFA_RISK
121978.1247445	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153030	41.0	None	5/1/71	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:feces	no	15.34	None	stool	2/19/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8636	121978	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121978	8636 stool	CCFA_RISK
SKBTI.0121.1246637	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122974	6.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	12/2/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0488	SKBTI.0121	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0121	M1-0488 biopsy	CCFA_RISK
SKBTI.0570.1247123	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133806	14.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	6/14/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0462	SKBTI.0570	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0570	M1-0462 biopsy	CCFA_RISK
100003.1246884	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125816	26.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100003	100003	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100003	OR100003 stool	CCFA_RISK
SKBTI.1136.1246957	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162339	14.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	8/9/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0795	SKBTI.1136	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1136	M1-0795 biopsy	CCFA_RISK
100001.1247426	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125815	19.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100001	100001	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100001	OR100001 stool	CCFA_RISK
SKBTI.1072.1247135	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161038	7.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	10/25/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0087	SKBTI.1072	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1072	M1-0087 biopsy	CCFA_RISK
SKBTI.1013.1246730	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161135	13.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	5/12/10	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0362	SKBTI.1013	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1013	M1-0362 biopsy	CCFA_RISK
100191.1246961	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127118	41.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100191	100191	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100191	OR100191 stool	CCFA_RISK
SKBTI.0583.1246788	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133704	11.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/23/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0510	SKBTI.0583	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0583	M1-0510 biopsy	CCFA_RISK
121180.1246978	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136297	31.0	None	11/12/80	human	0	9606	MiSeq	human gut metagenome	female	None	9	UBERON:feces	None	15.34	None	stool	3/11/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8458	121180	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121180	8458 stool	CCFA_RISK
122072.1246419	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153009	30.0	None	10/8/82	human	0	9606	MiSeq	human gut metagenome	female	no	1	UBERON:feces	no	15.34	None	stool	3/5/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8582	122072	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122072	8582 stool	CCFA_RISK
SKBTI.0741.1246770	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135655	7.666666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	5/16/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0323	SKBTI.0741	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0741	M1-0323 biopsy	CCFA_RISK
SKBTI.0273.1247229	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123128	11.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/30/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0537	SKBTI.0273	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0273	M1-0537 biopsy	CCFA_RISK
SKBTI.0872.1247209	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146976	16.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	2/16/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0484	SKBTI.0872	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0872	M1-0484 biopsy	CCFA_RISK
SKBTI.0643.1246702	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133778	13.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	7/5/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0283	SKBTI.0643	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0643	M1-0283 biopsy	CCFA_RISK
SKBTI.1123.1247207	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162333	6.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/14/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0458	SKBTI.1123	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1123	M1-0458 biopsy	CCFA_RISK
SKBTI.0150.1246545	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136010	12.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	10/27/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0596	SKBTI.0150	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0150	M1-0596 biopsy	CCFA_RISK
SKBTI021.1246850	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106892	8.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	9/9/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0563	SKBTI021	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI021	M1-0563 biopsy	CCFA_RISK
SKBTI.0541.1246998	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133688	8.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/31/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0280	SKBTI.0541	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0541	M1-0280 biopsy	CCFA_RISK
SKBTI.1197.1247292	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162365	11.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	2/1/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0735	SKBTI.1197	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1197	M1-0735 biopsy	CCFA_RISK
SKBTI.0177.1247379	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123027	11.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/3/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0521	SKBTI.0177	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0177	M1-0521 biopsy	CCFA_RISK
MGH105450.1246607	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125892	58.0	no	1/14/50	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:colon	None	15.34	None	biopsy	12/10/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7361	MGH105450	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	MGH105450	7361 biopsy	CCFA_RISK
122164.1246355	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153073	29.0	None	7/1/83	human	0	9606	MiSeq	human gut metagenome	female	no	3	UBERON:feces	no	15.34	None	stool	12/6/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8670	122164	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	122164	8670 stool	CCFA_RISK
SKBTI.0422.1247247	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29E7.1.Solexa-124785	14.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	yes	15.34	None	biopsy	10/22/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0086	SKBTI.0422	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0422	M1-0086 biopsy	CCFA_RISK
SKBTI.0956.1247154	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147060	10.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	2/3/12	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0342	SKBTI.0956	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0956	M1-0342 biopsy	CCFA_RISK
SKBTI.0708.1246834	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135605	16.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	10/3/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0055	SKBTI.0708	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0708	M1-0055 biopsy	CCFA_RISK
SKBTI048.1247350	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106919	5.083333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/21/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0295	SKBTI048	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI048	M1-0295 biopsy	CCFA_RISK
SKBTI.1117.1247057	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161058	10.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	yes	15.34	None	biopsy	7/26/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0285	SKBTI.1117	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1117	M1-0285 biopsy	CCFA_RISK
MGH104421.1247120	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125752	38.0	no	7/16/70	human	0	9606	MiSeq	human gut metagenome	female	no	6	UBERON:colon	yes	15.34	None	biopsy	8/19/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7049	MGH104421	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Transverse colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH104421	7049 biopsy	CCFA_RISK
SKBTI.1224.1246466	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161106	9.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	1/27/10	0.0	no	ENVO:urban biome	None	Illumina	no	east_asian	BI	GAZ:United States of America	None	RISK	1939:M1-0759	SKBTI.1224	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1224	M1-0759 biopsy	CCFA_RISK
SKBTI.1183.1246467	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162355	16.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	2/24/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0659	SKBTI.1183	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1183	M1-0659 biopsy	CCFA_RISK
122058.1246184	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153015	38.0	None	5/31/74	human	0	9606	MiSeq	human gut metagenome	male	no	1	UBERON:feces	yes	15.34	None	stool	9/26/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8585	122058	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122058	8585 stool	CCFA_RISK
SKBTI.1112.1247280	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161053	15.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	None	15.34	None	biopsy	7/28/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0405	SKBTI.1112	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1112	M1-0405 biopsy	CCFA_RISK
MGH113486.1246459	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125738	53.0	no	8/20/56	human	0	9606	MiSeq	human gut metagenome	female	no	28	UBERON:rectum	no	15.34	None	biopsy	1/27/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7859	MGH113486	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	yes	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH113486	7859 biopsy	CCFA_RISK
SKBTI.0608.1246779	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133743	15.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	None	15.34	None	biopsy	6/29/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0671	SKBTI.0608	408170	BI	.1,g	L2	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0608	M1-0671 biopsy	CCFA_RISK
SKBTI.0228.1246851	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123083	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/24/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0303	SKBTI.0228	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0228	M1-0303 biopsy	CCFA_RISK
SKBTI.0918.1246997	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147022	5.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	1/24/12	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0604	SKBTI.0918	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0918	M1-0604 biopsy	CCFA_RISK
SKBTI.0916.1247466	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147020	13.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	12/9/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0708	SKBTI.0916	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0916	M1-0708 biopsy	CCFA_RISK
100128.1246258	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125863	8.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100128	100128	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	100128	OR100128 stool	CCFA_RISK
MGH103108.1246870	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125774	48.0	no	4/1/60	human	0	9606	MiSeq	human gut metagenome	male	yes	20	UBERON:ileum	yes	15.34	None	biopsy	4/29/08	0.0	yes	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Current	PRISM	1939:7126	MGH103108	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	yes	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH103108	7126 biopsy	CCFA_RISK
121214.1246862	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136321	26.0	None	10/11/85	human	0	9606	MiSeq	human gut metagenome	female	no	1	UBERON:feces	no	15.34	None	stool	5/15/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8511	121214	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121214	8511 stool	CCFA_RISK
SKBTI.0226.1247136	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135994	9.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	3/15/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0413	SKBTI.0226	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0226	M1-0413 biopsy	CCFA_RISK
122113.1246427	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153086	30.0	None	10/13/82	human	0	9606	MiSeq	human gut metagenome	female	no	11	UBERON:feces	no	15.34	None	stool	3/1/13	0.0	None	ENVO:urban biome	None	Illumina	None	other	BI	GAZ:United States of America	Never	PRISM	1939:8726	122113	408170	BI	.1,g	J-Pouch	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B2	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122113	8726 stool	CCFA_RISK
SKBTI.0219.1246800	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123075	10.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	yes	15.34	None	biopsy	3/31/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0358	SKBTI.0219	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0219	M1-0358 biopsy	CCFA_RISK
SKBTI.0266.1247285	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123121	11.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/22/11	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0456	SKBTI.0266	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0266	M1-0456 biopsy	CCFA_RISK
121478.1246295	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136406	21.0	None	3/30/89	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:feces	no	15.34	None	stool	3/7/11	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8129	121478	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121478	8129 stool	CCFA_RISK
SKBTI.1037.1246499	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162426	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	9/3/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0720	SKBTI.1037	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.1037	M1-0720 biopsy	CCFA_RISK
SKBTI.0977.1247053	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162405	8.166666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:colon	no	15.34	None	biopsy	10/22/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0025	SKBTI.0977	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0977	M1-0025 biopsy	CCFA_RISK
100047.1246185	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125822	31.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100047	100047	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100047	OR100047 stool	CCFA_RISK
SKBTI.1141.1246341	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162341	16.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	8/11/11	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0800	SKBTI.1141	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1141	M1-0800 biopsy	CCFA_RISK
SKBTI.0756.1247104	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-154972	12.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/27/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0579	SKBTI.0756	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0756	M1-0579 biopsy	CCFA_RISK
SKBTI.0884.1247441	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146988	11.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	yes	15.34	None	biopsy	3/1/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0271	SKBTI.0884	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0884	M1-0271 biopsy	CCFA_RISK
100062.1246762	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125829	12.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100062	100062	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	100062	OR100062 stool	CCFA_RISK
121479.1247255	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136407	62.0	None	4/30/48	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	3/8/11	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8197	121479	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121479	8197 stool	CCFA_RISK
SKBTI.0767.1246623	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155063	8.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	11/17/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0599	SKBTI.0767	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0767	M1-0599 biopsy	CCFA_RISK
SKBTI.0108.1246241	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122963	9.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	7/6/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0172	SKBTI.0108	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0108	M1-0172 biopsy	CCFA_RISK
122077.1246131	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153007	30.0	None	10/8/82	human	0	9606	MiSeq	human gut metagenome	female	no	1	UBERON:feces	no	15.34	None	stool	3/5/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8582	122077	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122077	8582 stool	CCFA_RISK
SKBTI.0277.1246562	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123131	13.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/24/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0117	SKBTI.0277	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0277	M1-0117 biopsy	CCFA_RISK
SKBTI.0676.1247410	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135688	14.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	12/14/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0146	SKBTI.0676	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0676	M1-0146 biopsy	CCFA_RISK
SKBTI088.1247300	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106959	8.666666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	12/13/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0650	SKBTI088	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI088	M1-0650 biopsy	CCFA_RISK
SKBTI.1010.1246481	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162421	15.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	5/7/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0237	SKBTI.1010	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1010	M1-0237 biopsy	CCFA_RISK
122053.1246378	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153053	67.0	None	5/22/45	human	0	9606	MiSeq	human gut metagenome	male	no	51	UBERON:feces	no	15.34	None	stool	1/10/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8692	122053	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	122053	8692 stool	CCFA_RISK
SKBTI.0124.1247131	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122976	13.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	9/10/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0213	SKBTI.0124	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0124	M1-0213 biopsy	CCFA_RISK
SKBTI.1286.1247055	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162457	13.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	8/25/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0843	SKBTI.1286	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1286	M1-0843 biopsy	CCFA_RISK
SKBTI.0206.1247297	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123062	10.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/20/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0352	SKBTI.0206	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0206	M1-0352 biopsy	CCFA_RISK
121450.1246156	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136367	42.0	None	3/9/70	human	0	9606	MiSeq	human gut metagenome	female	no	15	UBERON:feces	no	15.34	None	stool	9/19/12	0.0	None	ENVO:urban biome	None	Illumina	None	african	BI	GAZ:United States of America	Current	PRISM	1939:8563	121450	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121450	8563 stool	CCFA_RISK
SKBTI062.1246504	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106933	10.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/26/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0081	SKBTI062	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI062	M1-0081 biopsy	CCFA_RISK
121475.1246242	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136403	57.0	None	5/24/53	human	0	9606	MiSeq	human gut metagenome	female	no	28	UBERON:feces	no	15.34	None	stool	5/4/11	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:7445	121475	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121475	7445 stool	CCFA_RISK
SKBTI.1258.1246723	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161172	14.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:cecum	no	15.34	None	biopsy	4/14/11	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0797	SKBTI.1258	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1258	M1-0797 biopsy	CCFA_RISK
SKBTI.1067.1246307	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162306	15.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:colon	no	15.34	None	biopsy	10/14/10	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0039	SKBTI.1067	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1067	M1-0039 biopsy	CCFA_RISK
SKBTI.0115.1247421	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135939	15.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	11/2/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0351	SKBTI.0115	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0115	M1-0351 biopsy	CCFA_RISK
SKBTI.0912.1247348	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147016	13.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	12/22/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0474	SKBTI.0912	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0912	M1-0474 biopsy	CCFA_RISK
SKBTI.1149.1246179	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162438	16.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	8/16/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0755	SKBTI.1149	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1149	M1-0755 biopsy	CCFA_RISK
SKBTI.0645.1247145	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133780	16.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	6/14/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0077	SKBTI.0645	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0645	M1-0077 biopsy	CCFA_RISK
SKBTI031.1246276	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106902	15.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/22/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0079	SKBTI031	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI031	M1-0079 biopsy	CCFA_RISK
121422.1246561	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136359	34.0	None	7/15/75	human	0	9606	MiSeq	human gut metagenome	female	no	2	UBERON:feces	no	15.34	None	stool	5/5/10	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:7954	121422	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121422	7954 stool	CCFA_RISK
SKBTI.0935.1246261	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147039	15.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	5/26/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0363	SKBTI.0935	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0935	M1-0363 biopsy	CCFA_RISK
121308.1246337	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136336	51.0	None	8/13/61	human	0	9606	MiSeq	human gut metagenome	female	no	26	UBERON:feces	no	15.34	None	stool	9/11/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8485	121308	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B2	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121308	8485 stool	CCFA_RISK
SKBTI.0637.1246248	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133772	15.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	yes	15.34	None	biopsy	5/17/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0420	SKBTI.0637	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0637	M1-0420 biopsy	CCFA_RISK
SKBTI.1044.1247469	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161159	14.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	9/15/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0826	SKBTI.1044	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1044	M1-0826 biopsy	CCFA_RISK
SKBTI.1299.1247431	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162466	14.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	9/6/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0818	SKBTI.1299	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1299	M1-0818 biopsy	CCFA_RISK
SKBTI.0922.1247339	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147026	10.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	2/21/12	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0709	SKBTI.0922	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0922	M1-0709 biopsy	CCFA_RISK
SKBTI.1214.1246879	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161100	9.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	2/20/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0837	SKBTI.1214	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1214	M1-0837 biopsy	CCFA_RISK
SKBTI.1061.1246417	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161028	14.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	10/15/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0814	SKBTI.1061	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1061	M1-0814 biopsy	CCFA_RISK
SKBTI.1189.1246772	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161092	9.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	3/3/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0828	SKBTI.1189	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1189	M1-0828 biopsy	CCFA_RISK
100228.1246589	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127146	35.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100228	100228	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100228	OR100228 stool	CCFA_RISK
SKBTI.1020.1246239	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161141	15.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	6/16/10	0.0	no	ENVO:urban biome	None	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0825	SKBTI.1020	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1020	M1-0825 biopsy	CCFA_RISK
MGH102894.1247205	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125792	37.0	no	7/28/70	human	0	9606	MiSeq	human gut metagenome	female	no	6	UBERON:colon	no	15.34	None	biopsy	4/9/08	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7181	MGH102894	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	yes	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Ascending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH102894	7181 biopsy	CCFA_RISK
SKBTI.0968.1247333	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162398	10.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:cecum	no	15.34	None	biopsy	11/2/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0219	SKBTI.0968	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0968	M1-0219 biopsy	CCFA_RISK
SKBTI008.1247338	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106879	10.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	yes	15.34	None	biopsy	4/12/10	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0360	SKBTI008	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI008	M1-0360 biopsy	CCFA_RISK
121451.1246659	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136368	37.0	None	3/7/75	human	0	9606	MiSeq	human gut metagenome	female	no	22	UBERON:feces	no	15.34	None	stool	6/27/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8559	121451	408170	BI	.1,g	J-Pouch	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121451	8559 stool	CCFA_RISK
SKBTI.1022.1246350	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162424	3.333333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:colon	no	15.34	None	biopsy	5/18/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0792	SKBTI.1022	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Ascending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1022	M1-0792 biopsy	CCFA_RISK
SKBTI.0591.1247012	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133705	13.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/23/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0511	SKBTI.0591	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0591	M1-0511 biopsy	CCFA_RISK
SKBTI.0284.1247364	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123138	11.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	1/7/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0567	SKBTI.0284	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0284	M1-0567 biopsy	CCFA_RISK
SKBTI.0719.1246628	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155043	9.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	10/6/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0408	SKBTI.0719	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0719	M1-0408 biopsy	CCFA_RISK
SKBTI.0984.1246902	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162409	12.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:cecum	no	15.34	None	biopsy	1/27/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0223	SKBTI.0984	408170	BI	.1,g	L2	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0984	M1-0223 biopsy	CCFA_RISK
SKBTI.0886.1247252	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146990	16.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	2/12/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0293	SKBTI.0886	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0886	M1-0293 biopsy	CCFA_RISK
SKBTI.0531.1246710	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133666	11.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	5/19/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0434	SKBTI.0531	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0531	M1-0434 biopsy	CCFA_RISK
SKBTI.0286.1247033	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123140	8.083333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/13/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0102	SKBTI.0286	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0286	M1-0102 biopsy	CCFA_RISK
SKBTI062.1246572	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127159	10.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/26/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0081	SKBTI062	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI062	M1-0081 biopsy	CCFA_RISK
SKBTI.1209.1246285	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161097	16.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/29/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0694	SKBTI.1209	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1209	M1-0694 biopsy	CCFA_RISK
SKBTI.0684.1246689	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135696	9.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/17/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0075	SKBTI.0684	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0684	M1-0075 biopsy	CCFA_RISK
SKBTI.0662.1246426	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133797	6.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	8/16/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0469	SKBTI.0662	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0662	M1-0469 biopsy	CCFA_RISK
SKBTI.1218.1246167	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162375	12.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	12/8/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0767	SKBTI.1218	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1218	M1-0767 biopsy	CCFA_RISK
SKBTI.0135.1246390	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136072	16.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	9/1/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0367	SKBTI.0135	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0135	M1-0367 biopsy	CCFA_RISK
SKBTI.1238.1247200	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161110	16.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:cecum	no	15.34	None	biopsy	4/11/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0750	SKBTI.1238	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1238	M1-0750 biopsy	CCFA_RISK
MGH105239.1246905	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136035	60.0	no	4/15/48	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:colon	None	15.34	None	biopsy	11/19/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7360	MGH105239	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	MGH105239	7360 biopsy	CCFA_RISK
SKBTI066.1247166	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106937	10.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	10/15/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0177	SKBTI066	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI066	M1-0177 biopsy	CCFA_RISK
SKBTI.0144.1246362	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122996	11.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	8/13/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0254	SKBTI.0144	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0144	M1-0254 biopsy	CCFA_RISK
SKBTI.0244.1247190	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136001	14.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/7/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0684	SKBTI.0244	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0244	M1-0684 biopsy	CCFA_RISK
SKBTI.1029.1246449	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161148	9.416666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	11/9/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0528	SKBTI.1029	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1029	M1-0528 biopsy	CCFA_RISK
SKBTI.0122.1246656	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136071	12.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	12/11/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	yes	african	BI	GAZ:United States of America	None	RISK	1939:M1-0029	SKBTI.0122	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0122	M1-0029 biopsy	CCFA_RISK
SKBTI068.1246650	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106939	16.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	8/20/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0175	SKBTI068	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI068	M1-0175 biopsy	CCFA_RISK
SKBTI.1220.1246728	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161104	13.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	12/12/08	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0758	SKBTI.1220	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1220	M1-0758 biopsy	CCFA_RISK
SKBTI.0483.1247150	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133618	9.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/13/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0121	SKBTI.0483	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0483	M1-0121 biopsy	CCFA_RISK
121445.1247271	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136362	20.0	None	1/21/92	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:feces	yes	15.34	None	stool	8/1/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8599	121445	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121445	8599 stool	CCFA_RISK
SKBTI.0579.1247464	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133714	11.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/22/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0594	SKBTI.0579	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0579	M1-0594 biopsy	CCFA_RISK
MGH101123.1246369	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136046	53.0	yes	5/19/54	human	0	9606	MiSeq	human gut metagenome	female	no	9	UBERON:colon	no	15.34	None	biopsy	10/2/07	0.0	yes	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7097	MGH101123	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH101123	7097 biopsy	CCFA_RISK
MGH104824.1247230	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125888	46.0	yes	2/8/62	human	0	9606	MiSeq	human gut metagenome	male	no	17	UBERON:ileum	yes	15.34	None	biopsy	9/24/08	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7352	MGH104824	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH104824	7352 biopsy	CCFA_RISK
SKBTI.0245.1246270	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123100	8.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/7/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0685	SKBTI.0245	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0245	M1-0685 biopsy	CCFA_RISK
SKBTI.0678.1247402	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135690	10.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	None	15.34	None	biopsy	5/7/12	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0676	SKBTI.0678	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0678	M1-0676 biopsy	CCFA_RISK
SKBTI.0265.1246995	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123120	5.416666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	1/15/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0680	SKBTI.0265	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0265	M1-0680 biopsy	CCFA_RISK
SKBTI.0930.1247051	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147034	11.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/29/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0417	SKBTI.0930	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0930	M1-0417 biopsy	CCFA_RISK
SKBTI.1203.1246230	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162369	4.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	None	15.34	None	biopsy	2/9/12	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0786	SKBTI.1203	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1203	M1-0786 biopsy	CCFA_RISK
SKBTI.0982.1247037	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161117	None	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:cecum	no	15.34	None	biopsy	1/19/10	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0771	SKBTI.0982	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0982	M1-0771 biopsy	CCFA_RISK
SKBTI.1273.1247465	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162455	15.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	5/3/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0540	SKBTI.1273	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1273	M1-0540 biopsy	CCFA_RISK
SKBTI.0147.1247156	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122999	7.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/9/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0577	SKBTI.0147	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0147	M1-0577 biopsy	CCFA_RISK
121198.1246569	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136315	20.0	None	4/14/92	human	0	9606	MiSeq	human gut metagenome	male	no	1	UBERON:feces	no	15.34	None	stool	5/29/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8502	121198	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121198	8502 stool	CCFA_RISK
122119.1247288	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153043	21.0	None	8/2/91	human	0	9606	MiSeq	human gut metagenome	female	yes	1	UBERON:feces	yes	15.34	None	stool	3/4/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8649	122119	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122119	8649 stool	CCFA_RISK
SKBTI.0183.1246247	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123031	15.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	7/7/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0247	SKBTI.0183	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0183	M1-0247 biopsy	CCFA_RISK
SKBTI.1086.1246708	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162313	11.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	12/6/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0099	SKBTI.1086	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1086	M1-0099 biopsy	CCFA_RISK
SKBTI.0539.1247023	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133674	13.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/20/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0278	SKBTI.0539	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0539	M1-0278 biopsy	CCFA_RISK
SKBTI.0589.1247007	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133724	13.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/27/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0333	SKBTI.0589	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0589	M1-0333 biopsy	CCFA_RISK
SKBTI.0138.1246557	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122990	13.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	8/3/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0552	SKBTI.0138	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0138	M1-0552 biopsy	CCFA_RISK
121386.1246649	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136344	57.0	None	10/16/53	human	0	9606	MiSeq	human gut metagenome	female	no	31	UBERON:feces	no	15.34	None	stool	5/4/11	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:7843	121386	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B2	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121386	7843 stool	CCFA_RISK
SKBTI.0642.1246507	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133777	6.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/28/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0281	SKBTI.0642	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0642	M1-0281 biopsy	CCFA_RISK
SKBTI.0737.1247337	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135603	13.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	yes	15.34	None	biopsy	11/21/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0514	SKBTI.0737	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0737	M1-0514 biopsy	CCFA_RISK
SKBTI.1266.1246943	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162448	6.333333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/27/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0461	SKBTI.1266	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1266	M1-0461 biopsy	CCFA_RISK
SKBTI.0580.1246725	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133715	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/17/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0136	SKBTI.0580	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0580	M1-0136 biopsy	CCFA_RISK
SKBTI.0208.1246281	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123064	12.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	12/21/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0490	SKBTI.0208	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0208	M1-0490 biopsy	CCFA_RISK
SKBTI049.1247244	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106920	7.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/24/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0399	SKBTI049	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI049	M1-0399 biopsy	CCFA_RISK
MGH105841.1247387	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125770	41.0	yes	6/18/67	human	0	9606	MiSeq	human gut metagenome	male	no	25	UBERON:cecum	no	15.34	None	biopsy	3/3/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7117	MGH105841	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH105841	7117 biopsy	CCFA_RISK
SKBTI.1338.1247013	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161204	11.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	yes	15.34	None	biopsy	10/13/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0339	SKBTI.1338	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1338	M1-0339 biopsy	CCFA_RISK
SKBTI067.1246705	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106938	7.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	12/23/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0006	SKBTI067	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI067	M1-0006 biopsy	CCFA_RISK
SKBTI.0134.1246794	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135942	15.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	yes	15.34	None	biopsy	8/26/10	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0257	SKBTI.0134	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0134	M1-0257 biopsy	CCFA_RISK
SKBTI.0162.1246517	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123012	15.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	5/7/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0237	SKBTI.0162	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0162	M1-0237 biopsy	CCFA_RISK
SKBTI.1226.1247384	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162379	13.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	9/14/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0763	SKBTI.1226	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1226	M1-0763 biopsy	CCFA_RISK
SKBTI065.1247084	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106936	10.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	11/22/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0648	SKBTI065	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI065	M1-0648 biopsy	CCFA_RISK
MGH100695.1246812	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136043	35.0	no	3/15/72	human	0	9606	MiSeq	human gut metagenome	male	no	20	UBERON:rectum	yes	15.34	None	biopsy	8/21/07	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7079	MGH100695	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	yes	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH100695	7079 biopsy	CCFA_RISK
121310.1247096	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136338	66.0	None	6/9/46	human	0	9606	MiSeq	human gut metagenome	female	no	14	UBERON:feces	no	15.34	None	stool	7/4/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8541	121310	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121310	8541 stool	CCFA_RISK
SKBTI.1255.1246440	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161170	5.083333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	7/21/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0295	SKBTI.1255	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1255	M1-0295 biopsy	CCFA_RISK
SKBTI.0652.1246739	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155019	10.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	5/13/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0518	SKBTI.0652	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0652	M1-0518 biopsy	CCFA_RISK
122006.1246809	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153031	23.0	None	2/13/89	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:feces	no	15.34	None	stool	11/15/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8646	122006	408170	BI	.1,g	E1	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	122006	8646 stool	CCFA_RISK
121282.1246224	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136331	22.0	None	10/26/89	human	0	9606	MiSeq	human gut metagenome	male	no	4	UBERON:feces	no	15.34	None	stool	8/6/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8595	121282	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121282	8595 stool	CCFA_RISK
SKBTI039.1246775	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106910	14.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	12/30/09	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0032	SKBTI039	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI039	M1-0032 biopsy	CCFA_RISK
100183.1246704	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127113	24.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100183	100183	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	yes	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100183	OR100183 stool	CCFA_RISK
121495.1246143	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136415	37.0	None	10/1/74	human	0	9606	MiSeq	human gut metagenome	female	no	12	UBERON:feces	yes	15.34	None	stool	4/11/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:7122	121495	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121495	7122 stool	CCFA_RISK
SKBTI.0700.1247095	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135620	13.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	11/3/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0091	SKBTI.0700	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0700	M1-0091 biopsy	CCFA_RISK
SKBTI.1055.1247319	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161166	14.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	None	15.34	None	biopsy	9/28/10	0.0	no	ENVO:urban biome	None	Illumina	no	east_asian	BI	GAZ:United States of America	None	RISK	1939:M1-0390	SKBTI.1055	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1055	M1-0390 biopsy	CCFA_RISK
SKBTI091.1247453	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127152	16.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	12/6/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0649	SKBTI091	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI091	M1-0649 biopsy	CCFA_RISK
SKBTI046.1246959	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127162	16.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/27/10	0.0	no	ENVO:urban biome	None	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0168	SKBTI046	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI046	M1-0168 biopsy	CCFA_RISK
SKBTI.0869.1247257	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146973	16.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	None	15.34	None	biopsy	1/19/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0652	SKBTI.0869	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0869	M1-0652 biopsy	CCFA_RISK
SKBTI.0913.1246936	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147017	16.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	12/16/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0516	SKBTI.0913	408170	BI	.1,g	L1	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0913	M1-0516 biopsy	CCFA_RISK
SKBTI.0484.1247458	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133619	14.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/12/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0457	SKBTI.0484	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0484	M1-0457 biopsy	CCFA_RISK
SKBTI.0664.1247460	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133799	16.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	9/1/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0367	SKBTI.0664	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0664	M1-0367 biopsy	CCFA_RISK
100009.1247231	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125817	55.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100009	100009	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100009	OR100009 stool	CCFA_RISK
SKBTI.1314.1246910	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162476	9.666666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/10/12	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0737	SKBTI.1314	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1314	M1-0737 biopsy	CCFA_RISK
100099.1247449	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125852	83.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100099	100099	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100099	OR100099 stool	CCFA_RISK
MGH103660.1247375	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125756	53.0	yes	9/16/54	human	0	9606	MiSeq	human gut metagenome	male	no	32	UBERON:ileum	no	15.34	None	biopsy	6/17/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	yes	None	BI	GAZ:United States of America	Never	PRISM	1939:7064	MGH103660	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH103660	7064 biopsy	CCFA_RISK
SKBTI.0261.1247357	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123116	12.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/21/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0687	SKBTI.0261	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0261	M1-0687 biopsy	CCFA_RISK
SKBTI.0123.1246312	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123043	8.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	12/11/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0489	SKBTI.0123	408170	BI	.1,g	L3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0123	M1-0489 biopsy	CCFA_RISK
SKBTI004.1246380	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106875	10.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	2/5/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0205	SKBTI004	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI004	M1-0205 biopsy	CCFA_RISK
SKBTI.1165.1246502	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161082	13.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	8/10/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0286	SKBTI.1165	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1165	M1-0286 biopsy	CCFA_RISK
121968.1247455	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153054	31.0	None	12/4/81	human	0	9606	MiSeq	human gut metagenome	male	no	6	UBERON:feces	no	15.34	None	stool	1/23/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8700	121968	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121968	8700 stool	CCFA_RISK
SKBTI.0883.1246205	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146987	9.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	2/25/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0186	SKBTI.0883	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0883	M1-0186 biopsy	CCFA_RISK
SKBTI.0658.1246553	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133793	10.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	8/2/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0336	SKBTI.0658	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0658	M1-0336 biopsy	CCFA_RISK
SKBTI.0878.1246465	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146982	12.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	2/8/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0430	SKBTI.0878	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0878	M1-0430 biopsy	CCFA_RISK
MGH112373.1246418	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125726	44.0	no	7/16/65	human	0	9606	MiSeq	human gut metagenome	female	no	16	UBERON:colon	no	15.34	None	biopsy	12/9/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7584	MGH112373	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH112373	7584 biopsy	CCFA_RISK
SKBTI.0588.1247477	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133723	11.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/28/11	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0137	SKBTI.0588	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0588	M1-0137 biopsy	CCFA_RISK
SKBTI.1168.1247199	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161084	10.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	7/21/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0742	SKBTI.1168	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1168	M1-0742 biopsy	CCFA_RISK
SKBTI.0243.1246262	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123098	14.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	3/4/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0272	SKBTI.0243	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0243	M1-0272 biopsy	CCFA_RISK
SKBTI.0565.1246379	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133623	10.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/10/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0133	SKBTI.0565	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0565	M1-0133 biopsy	CCFA_RISK
SKBTI094.1247316	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106965	8.166666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	10/22/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0025	SKBTI094	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI094	M1-0025 biopsy	CCFA_RISK
MGH104671.1247429	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125772	37.0	yes	7/8/71	human	0	9606	MiSeq	human gut metagenome	female	no	10	UBERON:colon	no	15.34	None	biopsy	8/10/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7124	MGH104671	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH104671	7124 biopsy	CCFA_RISK
SKBTI074.1246706	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106945	10.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	12/23/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0030	SKBTI074	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI074	M1-0030 biopsy	CCFA_RISK
SKBTI.0395.1246393	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-154986	15.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	10/19/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0262	SKBTI.0395	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0395	M1-0262 biopsy	CCFA_RISK
SKBTI.1333.1246382	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161201	11.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	10/12/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0729	SKBTI.1333	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1333	M1-0729 biopsy	CCFA_RISK
SKBTI.0648.1246473	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133783	12.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/23/10	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0310	SKBTI.0648	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0648	M1-0310 biopsy	CCFA_RISK
122004.1246297	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153048	30.0	None	12/1/82	human	0	9606	MiSeq	human gut metagenome	male	no	5	UBERON:feces	yes	15.34	None	stool	12/11/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8675	122004	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122004	8675 stool	CCFA_RISK
SKBTI.0244.1246930	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123099	14.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/7/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0684	SKBTI.0244	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0244	M1-0684 biopsy	CCFA_RISK
122096.1246993	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153042	21.0	None	8/2/91	human	0	9606	MiSeq	human gut metagenome	female	yes	1	UBERON:feces	yes	15.34	None	stool	3/4/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8649	122096	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122096	8649 stool	CCFA_RISK
100233.1246246	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127148	19.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100233	100233	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100233	OR100233 stool	CCFA_RISK
121983.1246348	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153033	23.0	None	2/13/89	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:feces	no	15.34	None	stool	12/10/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8646	121983	408170	BI	.1,g	E1	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121983	8646 stool	CCFA_RISK
SKBTI.0280.1246774	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123134	9.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/13/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0121	SKBTI.0280	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0280	M1-0121 biopsy	CCFA_RISK
SKBTI034.1246776	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106905	15.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	yes	15.34	None	biopsy	7/27/09	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0060	SKBTI034	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI034	M1-0060 biopsy	CCFA_RISK
SKBTI.0298.1246976	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29E7.1.Solexa-124661	15.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	yes	15.34	None	biopsy	2/3/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0531	SKBTI.0298	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0298	M1-0531 biopsy	CCFA_RISK
SKBTI.1328.1247203	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162482	15.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	10/5/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0802	SKBTI.1328	408170	BI	.1,g	L3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1328	M1-0802 biopsy	CCFA_RISK
SKBTI055.1247115	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106926	11.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/15/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0010	SKBTI055	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI055	M1-0010 biopsy	CCFA_RISK
SKBTI.1075.1246420	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161041	12.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	10/27/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0596	SKBTI.1075	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1075	M1-0596 biopsy	CCFA_RISK
100090.1246912	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125847	13.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100090	100090	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	100090	OR100090 stool	CCFA_RISK
120156.1246895	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136292	30.0	None	1/14/79	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	1/13/10	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:7844	120156	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	None	no	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	121159	7844 stool	CCFA_RISK
SKBTI036.1246510	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106907	11.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/8/09	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0008	SKBTI036	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI036	M1-0008 biopsy	CCFA_RISK
SKBTI.1052.1246226	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161165	7.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	9/24/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0260	SKBTI.1052	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1052	M1-0260 biopsy	CCFA_RISK
SKBTI.1307.1247068	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162470	5.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	5/2/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0155	SKBTI.1307	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1307	M1-0155 biopsy	CCFA_RISK
121420.1247325	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136357	None	None	11/20/82	human	0	9606	MiSeq	human gut metagenome	male	no	None	UBERON:feces	no	15.34	None	stool	None	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:7789	121420	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121420	7789 stool	CCFA_RISK
MGH105618.1247374	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125742	28.0	no	6/3/80	human	0	9606	MiSeq	human gut metagenome	male	no	5	UBERON:ileum	no	15.34	None	biopsy	1/14/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7007	MGH105618	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH105618	7007 biopsy	CCFA_RISK
SKBTI.1049.1246565	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162429	11.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	9/20/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0259	SKBTI.1049	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1049	M1-0259 biopsy	CCFA_RISK
SKBTI.1235.1246803	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162384	11.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/11/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0690	SKBTI.1235	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1235	M1-0690 biopsy	CCFA_RISK
MGH109614.1246972	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125728	69.0	no	2/4/40	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:colon	None	15.34	None	biopsy	8/24/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	None	PRISM	1939:7610	MGH109614	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	MGH109614	7610 biopsy	CCFA_RISK
SKBTI.0263.1247241	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123118	10.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	yes	15.34	None	biopsy	1/24/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0681	SKBTI.0263	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0263	M1-0681 biopsy	CCFA_RISK
121482.1247262	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136410	64.0	None	8/23/48	human	0	9606	MiSeq	human gut metagenome	female	no	1	UBERON:feces	no	15.34	None	stool	10/23/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8503	121482	408170	BI	.1,g	E1	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121482	8503 stool	CCFA_RISK
SKBTI.0566.1246220	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133633	12.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/14/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0134	SKBTI.0566	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0566	M1-0134 biopsy	CCFA_RISK
SKBTI.0765.1246651	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135678	8.666666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	1/24/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0398	SKBTI.0765	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0765	M1-0398 biopsy	CCFA_RISK
121389.1246126	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136347	65.0	None	6/1/46	human	0	9606	MiSeq	human gut metagenome	male	no	10	UBERON:feces	no	15.34	None	stool	2/6/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8447	121389	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121389	8447 stool	CCFA_RISK
SKBTI.0486.1246471	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133621	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	4/14/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0320	SKBTI.0486	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0486	M1-0320 biopsy	CCFA_RISK
SKBTI.0204.1247065	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123060	15.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	1/12/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0478	SKBTI.0204	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0204	M1-0478 biopsy	CCFA_RISK
100209.1247393	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127131	11.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100209	100209	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	yes	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100209	OR100209 stool	CCFA_RISK
SKBTI.1335.1246899	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162484	13.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	None	15.34	None	biopsy	10/12/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0844	SKBTI.1335	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1335	M1-0844 biopsy	CCFA_RISK
121195.1246166	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136312	30.0	None	3/13/82	human	0	9606	MiSeq	human gut metagenome	male	no	2	UBERON:feces	no	15.34	None	stool	6/4/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8374	121195	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121195	8374 stool	CCFA_RISK
SKBTI.0528.1246670	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133663	12.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	None	15.34	None	biopsy	5/16/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0663	SKBTI.0528	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0528	M1-0663 biopsy	CCFA_RISK
SKBTI.0194.1246488	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123052	6.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	yes	15.34	None	biopsy	8/2/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0250	SKBTI.0194	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0194	M1-0250 biopsy	CCFA_RISK
SKBTI.0989.1246840	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162413	7.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:cecum	no	15.34	None	biopsy	1/29/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0300	SKBTI.0989	408170	BI	.1,g	L1	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0989	M1-0300 biopsy	CCFA_RISK
SKBTI.1043.1246489	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162428	14.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	yes	15.34	None	biopsy	11/10/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0572	SKBTI.1043	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1043	M1-0572 biopsy	CCFA_RISK
SKBTI.0877.1246934	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146981	16.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	2/18/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0110	SKBTI.0877	408170	BI	.1,g	L2	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0877	M1-0110 biopsy	CCFA_RISK
SKBTI.0173.1246354	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135951	14.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/20/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0421	SKBTI.0173	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0173	M1-0421 biopsy	CCFA_RISK
MGH113364.1247340	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125727	28.0	no	10/7/81	human	0	9606	MiSeq	human gut metagenome	female	no	13	UBERON:ileum	yes	15.34	None	biopsy	1/25/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7594	MGH113364	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	yes	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH113364	7594 biopsy	CCFA_RISK
SKBTI.0865.1246401	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146969	9.166666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	12/30/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0530	SKBTI.0865	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0865	M1-0530 biopsy	CCFA_RISK
SKBTI.0892.1246132	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146996	13.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	None	15.34	None	biopsy	5/31/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0634	SKBTI.0892	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0892	M1-0634 biopsy	CCFA_RISK
121500.1247250	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136420	22.0	None	1/17/90	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:feces	no	15.34	None	stool	9/17/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8600	121500	408170	BI	.1,g	E3	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	121500	8600 stool	CCFA_RISK
SKBTI.0492.1246783	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133627	11.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	None	15.34	None	biopsy	4/8/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0629	SKBTI.0492	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0492	M1-0629 biopsy	CCFA_RISK
122009.1246683	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153046	31.0	None	6/12/81	human	0	9606	MiSeq	human gut metagenome	female	None	18	UBERON:feces	None	15.34	None	stool	11/14/12	0.0	None	ENVO:urban biome	None	Illumina	None	other	BI	GAZ:United States of America	Former	PRISM	1939:8658	122009	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	122009	8658 stool	CCFA_RISK
121279.1246886	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136328	29.0	None	10/8/82	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:feces	no	15.34	None	stool	7/17/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8582	121279	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121279	8582 stool	CCFA_RISK
SKBTI.0595.1247237	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155013	13.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/29/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0638	SKBTI.0595	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0595	M1-0638 biopsy	CCFA_RISK
SKBTI093.1246214	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106964	12.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	2/8/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0354	SKBTI093	408170	BI	.1,g	L1	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI093	M1-0354 biopsy	CCFA_RISK
SKBTI.1324.1246819	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161196	9.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	10/3/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0773	SKBTI.1324	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1324	M1-0773 biopsy	CCFA_RISK
SKBTI.1289.1247274	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162460	14.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	8/29/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0728	SKBTI.1289	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1289	M1-0728 biopsy	CCFA_RISK
SKBTI.1263.1246506	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162446	16.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	4/21/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0124	SKBTI.1263	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1263	M1-0124 biopsy	CCFA_RISK
100071.1247048	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125833	43.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100071	100071	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100071	OR100071 stool	CCFA_RISK
SKBTI.1242.1246188	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162389	14.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	3/28/11	0.0	no	ENVO:urban biome	None	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0371	SKBTI.1242	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1242	M1-0371 biopsy	CCFA_RISK
100105.1247327	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125857	55.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100105	100105	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100105	OR100105 stool	CCFA_RISK
SKBTI.1248.1247428	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161112	16.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	2/12/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0293	SKBTI.1248	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1248	M1-0293 biopsy	CCFA_RISK
121385.1246584	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136343	34.0	None	2/17/77	human	0	9606	MiSeq	human gut metagenome	male	no	21	UBERON:feces	yes	15.34	None	stool	5/25/11	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:7791	121385	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121385	7791 stool	CCFA_RISK
SKBTI.1053.1246926	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162431	6.083333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:cecum	no	15.34	None	biopsy	10/1/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0553	SKBTI.1053	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.1053	M1-0553 biopsy	CCFA_RISK
SKBTI.0160.1246964	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123011	11.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/29/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0417	SKBTI.0160	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0160	M1-0417 biopsy	CCFA_RISK
SKBTI.1340.1247165	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161206	8.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	10/14/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0340	SKBTI.1340	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1340	M1-0340 biopsy	CCFA_RISK
SKBTI.0276.1246951	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123130	8.166666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	4/4/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0274	SKBTI.0276	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0276	M1-0274 biopsy	CCFA_RISK
100048.1246661	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125823	50.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100048	100048	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100048	OR100048 stool	CCFA_RISK
SKBTI.1070.1246370	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161036	16.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:cecum	no	15.34	None	biopsy	10/19/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0501	SKBTI.1070	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1070	M1-0501 biopsy	CCFA_RISK
121480.1247162	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136408	41.0	None	11/16/70	human	0	9606	MiSeq	human gut metagenome	male	no	15	UBERON:feces	no	15.34	None	stool	10/24/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8264	121480	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121480	8264 stool	CCFA_RISK
SKBTI.1227.1246129	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162380	15.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	9/15/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0764	SKBTI.1227	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1227	M1-0764 biopsy	CCFA_RISK
SKBTI.1094.1247346	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162320	9.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	3/3/10	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0384	SKBTI.1094	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1094	M1-0384 biopsy	CCFA_RISK
121219.1247140	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136326	34.0	None	12/7/77	human	0	9606	MiSeq	human gut metagenome	female	no	2	UBERON:feces	no	15.34	None	stool	8/10/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8591	121219	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121219	8591 stool	CCFA_RISK
SKBTI.0247.1247343	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123102	8.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/8/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0050	SKBTI.0247	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0247	M1-0050 biopsy	CCFA_RISK
SKBTI.1155.1246722	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161078	8.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	7/27/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0624	SKBTI.1155	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1155	M1-0624 biopsy	CCFA_RISK
SKBTI.0604.1246336	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133739	14.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	6/29/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0332	SKBTI.0604	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0604	M1-0332 biopsy	CCFA_RISK
SKBTI.1153.1247397	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161076	12.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	7/27/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0547	SKBTI.1153	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1153	M1-0547 biopsy	CCFA_RISK
SKBTI095.1246731	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-107058	14.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	9/14/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0064	SKBTI095	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI095	M1-0064 biopsy	CCFA_RISK
SKBTI.0199.1247181	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123056	13.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/7/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0416	SKBTI.0199	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0199	M1-0416 biopsy	CCFA_RISK
MGH101666.1246883	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125884	57.0	no	3/21/50	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:rectum	None	15.34	None	biopsy	12/17/07	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7298	MGH101666	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	MGH101666	7298 biopsy	CCFA_RISK
SKBTI041.1246632	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106912	8.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	10/21/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0179	SKBTI041	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI041	M1-0179 biopsy	CCFA_RISK
SKBTI052.1247066	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106923	4.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/26/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0106	SKBTI052	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI052	M1-0106 biopsy	CCFA_RISK
MGH100896.1247293	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125875	34.0	yes	2/16/73	human	0	9606	MiSeq	human gut metagenome	female	no	6	UBERON:ileum	no	15.34	None	biopsy	9/11/07	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7094	MGH100896	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B3	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH100896	7094 biopsy	CCFA_RISK
SKBTI.0521.1246921	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133656	7.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	yes	15.34	None	biopsy	5/12/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0277	SKBTI.0521	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0521	M1-0277 biopsy	CCFA_RISK
121969.1247036	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153037	21.0	None	8/2/91	human	0	9606	MiSeq	human gut metagenome	female	yes	1	UBERON:feces	yes	15.34	None	stool	11/8/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8649	121969	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121969	8649 stool	CCFA_RISK
121196.1247031	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136313	38.0	None	6/6/73	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:feces	no	15.34	None	stool	6/1/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8477	121196	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121196	8477 stool	CCFA_RISK
SKBTI.0937.1247302	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147041	11.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	6/8/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0309	SKBTI.0937	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0937	M1-0309 biopsy	CCFA_RISK
SKBTI029.1246737	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106900	15.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	9/9/09	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0024	SKBTI029	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI029	M1-0024 biopsy	CCFA_RISK
122117.1247175	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153066	21.0	None	8/2/91	human	0	9606	MiSeq	human gut metagenome	female	yes	1	UBERON:feces	yes	15.34	None	stool	3/4/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8649	122117	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122117	8649 stool	CCFA_RISK
SKBTI.0533.1246396	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133668	11.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	5/17/11	0.0	no	ENVO:urban biome	None	Illumina	no	east_asian	BI	GAZ:United States of America	None	RISK	1939:M1-0602	SKBTI.0533	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0533	M1-0602 biopsy	CCFA_RISK
SKBTI.0481.1246986	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133616	8.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/20/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0123	SKBTI.0481	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0481	M1-0123 biopsy	CCFA_RISK
SKBTI.0214.1246893	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123070	5.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	2/15/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0224	SKBTI.0214	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0214	M1-0224 biopsy	CCFA_RISK
SKBTI.0178.1246646	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135956	15.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	None	15.34	None	biopsy	5/17/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0385	SKBTI.0178	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0178	M1-0385 biopsy	CCFA_RISK
SKBTI.0240.1246634	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123095	16.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/3/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0612	SKBTI.0240	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0240	M1-0612 biopsy	CCFA_RISK
SKBTI.0759.1247269	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135672	10.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	7/26/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0081	SKBTI.0759	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0759	M1-0081 biopsy	CCFA_RISK
SKBTI.0568.1246405	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133678	11.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/14/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0403	SKBTI.0568	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0568	M1-0403 biopsy	CCFA_RISK
122078.1246162	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153014	38.0	None	5/31/74	human	0	9606	MiSeq	human gut metagenome	male	no	1	UBERON:feces	yes	15.34	None	stool	9/4/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8585	122078	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122078	8585 stool	CCFA_RISK
SKBTI.1259.1247265	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161173	14.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	4/14/11	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0797	SKBTI.1259	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1259	M1-0797 biopsy	CCFA_RISK
122096.1247400	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153067	21.0	None	8/2/91	human	0	9606	MiSeq	human gut metagenome	female	yes	1	UBERON:feces	yes	15.34	None	stool	3/4/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8649	122096	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122096	8649 stool	CCFA_RISK
SKBTI.0537.1246513	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133672	14.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	yes	15.34	None	biopsy	5/23/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0128	SKBTI.0537	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0537	M1-0128 biopsy	CCFA_RISK
SKBTI.1225.1246395	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162378	9.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	8/23/11	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0762	SKBTI.1225	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1225	M1-0762 biopsy	CCFA_RISK
SKBTI.1128.1246963	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162337	11.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	8/3/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0468	SKBTI.1128	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1128	M1-0468 biopsy	CCFA_RISK
121388.1246171	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136346	68.0	None	9/22/42	human	0	9606	MiSeq	human gut metagenome	female	no	3	UBERON:feces	no	15.34	None	stool	1/4/11	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8112	121388	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121388	8112 stool	CCFA_RISK
SKBTI.0931.1247311	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147035	16.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	4/28/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0034	SKBTI.0931	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0931	M1-0034 biopsy	CCFA_RISK
SKBTI.0149.1246577	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123001	9.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	11/10/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0483	SKBTI.0149	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0149	M1-0483 biopsy	CCFA_RISK
100085.1246334	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125842	34.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100085	100085	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100085	OR100085 stool	CCFA_RISK
SKBTI.0954.1246174	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147058	10.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	2/8/12	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0149	SKBTI.0954	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0954	M1-0149 biopsy	CCFA_RISK
SKBTI.1068.1246950	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161034	16.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	10/19/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0501	SKBTI.1068	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1068	M1-0501 biopsy	CCFA_RISK
SKBTI.0482.1246693	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133617	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/5/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0539	SKBTI.0482	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0482	M1-0539 biopsy	CCFA_RISK
SKBTI.1019.1246282	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161140	13.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	6/14/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0242	SKBTI.1019	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1019	M1-0242 biopsy	CCFA_RISK
100180.1246973	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127110	50.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100180	100180	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100180	OR100180 stool	CCFA_RISK
SKBTI.1260.1246828	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162444	14.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	yes	15.34	None	biopsy	4/19/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0459	SKBTI.1260	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1260	M1-0459 biopsy	CCFA_RISK
SKBTI.1308.1246296	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161191	8.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/24/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0823	SKBTI.1308	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1308	M1-0823 biopsy	CCFA_RISK
100163.1246125	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125868	20.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100163	100163	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	yes	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100163	OR100163 stool	CCFA_RISK
SKBTI.0671.1247010	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135617	16.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	5/24/10	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0076	SKBTI.0671	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0671	M1-0076 biopsy	CCFA_RISK
SKBTI.0980.1246677	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162407	13.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:cecum	no	15.34	None	biopsy	2/9/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0302	SKBTI.0980	408170	BI	.1,g	L2	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0980	M1-0302 biopsy	CCFA_RISK
100104.1247040	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125856	44.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	2	OSCCAR	1939:OR100104	100104	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100104	OR100104 stool	CCFA_RISK
100177.1246647	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127108	39.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	yes	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100177	100177	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100177	OR100177 stool	CCFA_RISK
SKBTI.0448.1246164	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29E7.1.Solexa-124811	11.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	11/11/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0181	SKBTI.0448	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0448	M1-0181 biopsy	CCFA_RISK
SKBTI.1327.1246128	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162481	15.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	10/5/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0802	SKBTI.1327	408170	BI	.1,g	L3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1327	M1-0802 biopsy	CCFA_RISK
100197.1246801	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127122	7.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100197	100197	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100197	OR100197 stool	CCFA_RISK
SKBTI064.1246302	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106935	9.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	12/23/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0031	SKBTI064	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI064	M1-0031 biopsy	CCFA_RISK
SKBTI.1032.1247227	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162425	13.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	11/3/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0091	SKBTI.1032	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.1032	M1-0091 biopsy	CCFA_RISK
100212.1247085	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127134	66.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100212	100212	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100212	OR100212 stool	CCFA_RISK
SKBTI020.1246452	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106891	10.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	10/22/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0180	SKBTI020	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI020	M1-0180 biopsy	CCFA_RISK
SKBTI.1064.1247129	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161031	15.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:colon	no	15.34	None	biopsy	9/21/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0500	SKBTI.1064	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1064	M1-0500 biopsy	CCFA_RISK
MGH113059.1247179	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125733	25.0	no	8/1/84	human	0	9606	MiSeq	human gut metagenome	female	no	6	UBERON:ileum	no	15.34	None	biopsy	1/12/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7632	MGH113059	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	yes	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH113059	7632 biopsy	CCFA_RISK
SKBTI.1036.1247004	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161154	13.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	10/28/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0748	SKBTI.1036	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1036	M1-0748 biopsy	CCFA_RISK
SKBTI.0257.1246558	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123112	14.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/16/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0115	SKBTI.0257	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0257	M1-0115 biopsy	CCFA_RISK
SKBTI.1017.1246799	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161139	15.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	5/26/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0363	SKBTI.1017	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1017	M1-0363 biopsy	CCFA_RISK
MGH100079.1246631	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125839	53.0	no	3/13/54	human	0	9606	MiSeq	human gut metagenome	female	no	31	UBERON:ileum	no	15.34	None	biopsy	6/27/07	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7161	MGH100079	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B3	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH100079	7161 biopsy	CCFA_RISK
SKBTI.0495.1247332	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133630	15.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	yes	15.34	None	biopsy	4/8/11	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	other	BI	GAZ:United States of America	None	RISK	1939:M1-0119	SKBTI.0495	408170	BI	.1,g	L1	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0495	M1-0119 biopsy	CCFA_RISK
SKBTI.0201.1246869	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123058	9.166666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	None	15.34	None	biopsy	12/21/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0380	SKBTI.0201	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0201	M1-0380 biopsy	CCFA_RISK
MGH104413.1246703	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125784	22.0	yes	11/19/85	human	0	9606	MiSeq	human gut metagenome	male	no	3	UBERON:colon	no	15.34	None	biopsy	8/19/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7160	MGH104413	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH104413	7160 biopsy	CCFA_RISK
SKBTI.1354.1247212	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161022	10.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	10/26/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0378	SKBTI.1354	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1354	M1-0378 biopsy	CCFA_RISK
SKBTI.0998.1247434	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161126	15.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	None	15.34	None	biopsy	4/12/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0777	SKBTI.0998	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0998	M1-0777 biopsy	CCFA_RISK
SKBTI.0752.1246808	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135666	14.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	1/29/10	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0491	SKBTI.0752	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0752	M1-0491 biopsy	CCFA_RISK
SKBTI.0911.1246361	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147015	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	yes	15.34	None	biopsy	12/15/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0292	SKBTI.0911	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0911	M1-0292 biopsy	CCFA_RISK
SKBTI.0313.1246498	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29E7.1.Solexa-124676	16.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	2/24/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0659	SKBTI.0313	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0313	M1-0659 biopsy	CCFA_RISK
SKBTI.0542.1247221	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133677	13.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	yes	15.34	None	biopsy	5/24/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0324	SKBTI.0542	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0542	M1-0324 biopsy	CCFA_RISK
121446.1246612	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136363	57.0	None	9/30/54	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	7/21/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8589	121446	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	None	no	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	121446	8589 stool	CCFA_RISK
SKBTI.1269.1247030	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162451	12.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/27/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0373	SKBTI.1269	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1269	M1-0373 biopsy	CCFA_RISK
121447.1246283	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136364	26.0	None	10/13/85	human	0	9606	MiSeq	human gut metagenome	female	None	7	UBERON:feces	None	15.34	None	stool	7/21/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8586	121447	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	121447	8586 stool	CCFA_RISK
122099.1246903	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153087	30.0	None	10/13/82	human	0	9606	MiSeq	human gut metagenome	female	no	11	UBERON:feces	no	15.34	None	stool	3/1/13	0.0	None	ENVO:urban biome	None	Illumina	None	other	BI	GAZ:United States of America	Never	PRISM	1939:8726	122099	408170	BI	.1,g	J-Pouch	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B2	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122099	8726 stool	CCFA_RISK
100176.1246432	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127107	26.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	2	OSCCAR	1939:OR100176	100176	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	yes	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100176	OR100176 stool	CCFA_RISK
SKBTI.1015.1246193	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161137	13.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	None	15.34	None	biopsy	5/17/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0778	SKBTI.1015	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1015	M1-0778 biopsy	CCFA_RISK
SKBTI.0987.1246620	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162411	13.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	1/22/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0812	SKBTI.0987	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0987	M1-0812 biopsy	CCFA_RISK
SKBTI.1230.1246913	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161109	8.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	2/16/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0745	SKBTI.1230	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1230	M1-0745 biopsy	CCFA_RISK
SKBTI.0097.1247143	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122952	10.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	11/25/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	yes	african	BI	GAZ:United States of America	None	RISK	1939:M1-0002	SKBTI.0097	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0097	M1-0002 biopsy	CCFA_RISK
121952.1246685	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153081	31.0	None	12/4/81	human	0	9606	MiSeq	human gut metagenome	male	no	6	UBERON:feces	no	15.34	None	stool	1/23/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8700	121952	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121952	8700 stool	CCFA_RISK
SKBTI.0246.1247381	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123101	9.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/7/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0575	SKBTI.0246	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0246	M1-0575 biopsy	CCFA_RISK
SKBTI.0248.1247146	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123103	6.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/9/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0591	SKBTI.0248	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0248	M1-0591 biopsy	CCFA_RISK
SKBTI.0197.1246614	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123141	6.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	yes	15.34	None	biopsy	2/8/11	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0442	SKBTI.0197	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0197	M1-0442 biopsy	CCFA_RISK
SKBTI.1076.1246152	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161042	14.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	12/29/08	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0715	SKBTI.1076	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1076	M1-0715 biopsy	CCFA_RISK
SKBTI.0764.1246696	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155062	12.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	9/8/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0368	SKBTI.0764	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0764	M1-0368 biopsy	CCFA_RISK
SKBTI.1021.1246789	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162423	12.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	7/1/10	0.0	no	ENVO:urban biome	None	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0779	SKBTI.1021	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1021	M1-0779 biopsy	CCFA_RISK
MGH101763.1246575	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125740	20.0	no	6/3/87	human	0	9606	MiSeq	human gut metagenome	male	no	1	UBERON:ileum	yes	15.34	None	biopsy	12/19/07	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Current	PRISM	1939:7250	MGH101763	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B3	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Neo-ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH101763	7250 biopsy	CCFA_RISK
121280.1246751	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136329	38.0	None	5/31/74	human	0	9606	MiSeq	human gut metagenome	male	no	1	UBERON:feces	yes	15.34	None	stool	7/26/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8585	121280	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121280	8585 stool	CCFA_RISK
SKBTI.1349.1246563	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161019	15.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	10/7/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0616	SKBTI.1349	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1349	M1-0616 biopsy	CCFA_RISK
SKBTI.0951.1246127	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147055	12.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	12/9/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0426	SKBTI.0951	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0951	M1-0426 biopsy	CCFA_RISK
SKBTI.0279.1246859	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123133	2.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/14/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0122	SKBTI.0279	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0279	M1-0122 biopsy	CCFA_RISK
SKBTI009.1246949	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106880	14.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	yes	15.34	None	biopsy	3/31/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0359	SKBTI009	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI009	M1-0359 biopsy	CCFA_RISK
SKBTI.1279.1246495	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161177	11.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	8/25/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0783	SKBTI.1279	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1279	M1-0783 biopsy	CCFA_RISK
100060.1247170	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125828	60.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	2	OSCCAR	1939:OR100060	100060	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100060	OR100060 stool	CCFA_RISK
SKBTI.0159.1247391	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123010	16.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/28/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0034	SKBTI.0159	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0159	M1-0034 biopsy	CCFA_RISK
SKBTI037.1246306	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106908	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	11/24/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0182	SKBTI037	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI037	M1-0182 biopsy	CCFA_RISK
SKBTI.0995.1247413	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161123	10.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:cecum	yes	15.34	None	biopsy	3/31/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0358	SKBTI.0995	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0995	M1-0358 biopsy	CCFA_RISK
SKBTI054.1246675	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106925	12.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	12/28/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0162	SKBTI054	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI054	M1-0162 biopsy	CCFA_RISK
SKBTI.1296.1247105	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161185	12.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	yes	15.34	None	biopsy	8/18/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0790	SKBTI.1296	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1296	M1-0790 biopsy	CCFA_RISK
SKBTI.0527.1246814	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133662	11.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	yes	15.34	None	biopsy	6/28/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0422	SKBTI.0527	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0527	M1-0422 biopsy	CCFA_RISK
SKBTI.0638.1247079	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133773	9.666666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/17/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0494	SKBTI.0638	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0638	M1-0494 biopsy	CCFA_RISK
SKBTI.0102.1246554	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122957	4.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	1/20/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0202	SKBTI.0102	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0102	M1-0202 biopsy	CCFA_RISK
SKBTI.0278.1246500	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123132	15.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	3/30/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0051	SKBTI.0278	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0278	M1-0051 biopsy	CCFA_RISK
121154.1246277	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136296	65.0	None	6/15/45	human	0	9606	MiSeq	human gut metagenome	female	None	4	UBERON:feces	None	15.34	None	stool	5/4/11	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	None	PRISM	1939:7769	121154	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121179	7769 stool	CCFA_RISK
SKBTI.0411.1246559	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135982	4.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	11/11/10	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0605	SKBTI.0411	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0411	M1-0605 biopsy	CCFA_RISK
121405.1246611	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136356	42.0	None	4/13/70	human	0	9606	MiSeq	human gut metagenome	female	no	23	UBERON:feces	no	15.34	None	stool	9/30/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8616	121405	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121405	8616 stool	CCFA_RISK
MGH109781.1247141	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125731	64.0	yes	8/9/45	human	0	9606	MiSeq	human gut metagenome	male	no	24	UBERON:colon	no	15.34	None	biopsy	9/2/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7621	MGH109781	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH109781	7621 biopsy	CCFA_RISK
SKBTI.1105.1246830	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162324	12.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:colon	no	15.34	None	biopsy	7/25/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0842	SKBTI.1105	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1105	M1-0842 biopsy	CCFA_RISK
MGH113669.1247108	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125739	27.0	no	3/3/82	human	0	9606	MiSeq	human gut metagenome	female	None	9	UBERON:colon	None	15.34	None	biopsy	2/3/10	0.0	yes	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7871	MGH113669	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	MGH113669	7871 biopsy	CCFA_RISK
100049.1247075	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125824	46.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100049	100049	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100049	OR100049 stool	CCFA_RISK
121503.1247118	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136423	36.0	None	6/8/76	human	0	9606	MiSeq	human gut metagenome	male	no	17	UBERON:feces	no	15.34	None	stool	8/14/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8551	121503	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121503	8551 stool	CCFA_RISK
SKBTI019.1246984	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106890	14.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	12/10/08	0.0	no	ENVO:urban biome	inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0003	SKBTI019	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI019	M1-0003 biopsy	CCFA_RISK
SKBTI.1057.1247436	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161026	16.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	None	15.34	None	biopsy	10/11/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0391	SKBTI.1057	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1057	M1-0391 biopsy	CCFA_RISK
SKBTI.1090.1246539	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162317	11.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	12/10/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0394	SKBTI.1090	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1090	M1-0394 biopsy	CCFA_RISK
SKBTI.1098.1247042	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161048	14.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	yes	15.34	None	biopsy	10/22/10	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0086	SKBTI.1098	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1098	M1-0086 biopsy	CCFA_RISK
100078.1246603	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125838	31.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100078	100078	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	100078	OR100078 stool	CCFA_RISK
SKBTI.1074.1246979	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161040	15.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	10/27/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0721	SKBTI.1074	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1074	M1-0721 biopsy	CCFA_RISK
SKBTI.1184.1247184	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162356	14.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:cecum	no	15.34	None	biopsy	2/25/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0834	SKBTI.1184	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1184	M1-0834 biopsy	CCFA_RISK
SKBTI.0246.1246386	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136076	9.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/7/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0575	SKBTI.0246	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0246	M1-0575 biopsy	CCFA_RISK
100162.1247353	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125867	36.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100162	100162	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100162	OR100162 stool	CCFA_RISK
SKBTI.1034.1246338	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161152	11.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	11/16/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0821	SKBTI.1034	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1034	M1-0821 biopsy	CCFA_RISK
SKBTI.0173.1246792	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123023	14.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/20/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0421	SKBTI.0173	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0173	M1-0421 biopsy	CCFA_RISK
SKBTI.1323.1246671	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161195	8.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:cecum	no	15.34	None	biopsy	4/24/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0823	SKBTI.1323	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1323	M1-0823 biopsy	CCFA_RISK
MGH102203.1247017	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125743	41.0	no	12/10/66	human	0	9606	MiSeq	human gut metagenome	female	no	20	UBERON:colon	no	15.34	None	biopsy	2/20/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Current	PRISM	1939:7010	MGH102203	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Ascending colon	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH102203	7010 biopsy	CCFA_RISK
121476.1246989	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136404	63.0	None	11/19/46	human	0	9606	MiSeq	human gut metagenome	male	no	44	UBERON:feces	no	15.34	None	stool	4/7/10	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:7938	121476	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121476	7938 stool	CCFA_RISK
122117.1246729	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153041	21.0	None	8/2/91	human	0	9606	MiSeq	human gut metagenome	female	yes	1	UBERON:feces	yes	15.34	None	stool	3/4/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8649	122117	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122117	8649 stool	CCFA_RISK
SKBTI.0131.1246568	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122983	10.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	11/2/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0219	SKBTI.0131	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0131	M1-0219 biopsy	CCFA_RISK
SKBTI.1041.1246755	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161157	15.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	11/10/10	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0621	SKBTI.1041	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1041	M1-0621 biopsy	CCFA_RISK
SKBTI.0746.1246641	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155053	9.166666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	12/2/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0311	SKBTI.0746	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0746	M1-0311 biopsy	CCFA_RISK
SKBTI.0939.1246784	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147043	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	12/20/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0104	SKBTI.0939	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0939	M1-0104 biopsy	CCFA_RISK
SKBTI.1261.1246687	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162445	16.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	4/20/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0460	SKBTI.1261	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1261	M1-0460 biopsy	CCFA_RISK
SKBTI.0231.1246532	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123086	5.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	4/6/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0234	SKBTI.0231	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0231	M1-0234 biopsy	CCFA_RISK
SKBTI.0717.1246969	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135635	5.666666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	10/6/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0338	SKBTI.0717	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0717	M1-0338 biopsy	CCFA_RISK
SKBTI.1292.1246547	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162462	15.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	8/26/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0756	SKBTI.1292	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1292	M1-0756 biopsy	CCFA_RISK
MGH106271.1246415	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125883	57.0	yes	6/27/51	human	0	9606	MiSeq	human gut metagenome	male	no	19	UBERON:rectum	no	15.34	None	biopsy	4/7/09	0.0	yes	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7242	MGH106271	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH106271	7242 biopsy	CCFA_RISK
100077.1246422	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125837	15.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100077	100077	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100077	OR100077 stool	CCFA_RISK
SKBTI086.1247044	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106957	12.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	11/29/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0097	SKBTI086	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI086	M1-0097 biopsy	CCFA_RISK
SKBTI003.1246724	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127155	14.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	12/30/08	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0198	SKBTI003	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI003	M1-0198 biopsy	CCFA_RISK
MGH100695.1247456	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125760	35.0	no	3/15/72	human	0	9606	MiSeq	human gut metagenome	male	no	20	UBERON:rectum	yes	15.34	None	biopsy	8/21/07	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7079	MGH100695	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	yes	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH100695	7079 biopsy	CCFA_RISK
MGH104316.1246807	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136044	51.0	yes	5/25/57	human	0	9606	MiSeq	human gut metagenome	male	no	9	UBERON:colon	no	15.34	None	biopsy	8/5/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7287	MGH104316	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Transverse colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH104316	7287 biopsy	CCFA_RISK
SKBTI.0099.1246757	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122954	13.833	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	None	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0347	SKBTI.0099	408170	BI	.1,g	L1	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminalileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0099	biopsy M1-0347	CCFA_RISK
SKBTI.1065.1246587	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161032	15.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:cecum	no	15.34	None	biopsy	9/21/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0500	SKBTI.1065	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1065	M1-0500 biopsy	CCFA_RISK
SKBTI.0177.1246766	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136074	11.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/3/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0521	SKBTI.0177	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0177	M1-0521 biopsy	CCFA_RISK
121398.1247197	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136349	47.0	None	4/12/63	human	0	9606	MiSeq	human gut metagenome	male	no	8	UBERON:feces	no	15.34	None	stool	6/1/10	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:7492	121398	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121398	7492 stool	CCFA_RISK
SKBTI.1127.1246735	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162336	13.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	8/3/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0798	SKBTI.1127	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1127	M1-0798 biopsy	CCFA_RISK
100196.1246487	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127121	51.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	2	OSCCAR	1939:OR100196	100196	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	100196	OR100196 stool	CCFA_RISK
122101.1246391	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153013	30.0	None	10/8/82	human	0	9606	MiSeq	human gut metagenome	female	no	1	UBERON:feces	no	15.34	None	stool	3/5/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8582	122101	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122101	8582 stool	CCFA_RISK
100117.1247242	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125862	33.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100117	100117	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100117	OR100117 stool	CCFA_RISK
SKBTI071.1247028	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106942	7.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	2/9/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0355	SKBTI071	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI071	M1-0355 biopsy	CCFA_RISK
MGH111702.1246479	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125736	44.0	no	12/17/64	human	0	9606	MiSeq	human gut metagenome	female	no	16	UBERON:colon	no	15.34	None	biopsy	10/14/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7749	MGH111702	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH111702	7749 biopsy	CCFA_RISK
SKBTI.1232.1247225	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162382	14.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	3/4/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0590	SKBTI.1232	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1232	M1-0590 biopsy	CCFA_RISK
SKBTI.0548.1246238	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133683	13.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	None	15.34	None	biopsy	5/24/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0633	SKBTI.0548	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0548	M1-0633 biopsy	CCFA_RISK
122037.1247454	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153022	22.0	None	1/17/90	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:feces	no	15.34	None	stool	11/15/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8600	122037	408170	BI	.1,g	E3	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	122037	8600 stool	CCFA_RISK
SKBTI.1200.1247173	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162366	10.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	2/6/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0736	SKBTI.1200	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1200	M1-0736 biopsy	CCFA_RISK
SKBTI.1311.1247432	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162473	4.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	4/19/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0738	SKBTI.1311	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1311	M1-0738 biopsy	CCFA_RISK
SKBTI.1122.1247240	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162332	4.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	7/29/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0753	SKBTI.1122	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1122	M1-0753 biopsy	CCFA_RISK
100205.1246838	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127128	16.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100205	100205	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100205	OR100205 stool	CCFA_RISK
SKBTI.0985.1247086	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161119	12.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:cecum	no	15.34	None	biopsy	12/21/09	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0490	SKBTI.0985	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0985	M1-0490 biopsy	CCFA_RISK
SKBTI.1256.1246243	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161171	8.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	6/13/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0726	SKBTI.1256	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1256	M1-0726 biopsy	CCFA_RISK
MGH102965.1246437	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125759	37.0	yes	6/16/70	human	0	9606	MiSeq	human gut metagenome	female	no	2	UBERON:colon	no	15.34	None	biopsy	4/16/08	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7267	MGH102965	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH102965	7267 biopsy	CCFA_RISK
SKBTI.0949.1246937	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147053	16.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	11/24/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0096	SKBTI.0949	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0949	M1-0096 biopsy	CCFA_RISK
MGH104824.1247071	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136034	46.0	yes	2/8/62	human	0	9606	MiSeq	human gut metagenome	male	no	17	UBERON:ileum	yes	15.34	None	biopsy	9/24/08	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7352	MGH104824	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH104824	7352 biopsy	CCFA_RISK
121285.1246733	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136334	55.0	None	7/4/57	human	0	9606	MiSeq	human gut metagenome	male	None	7	UBERON:feces	None	15.34	None	stool	8/14/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8610	121285	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	121285	8610 stool	CCFA_RISK
SKBTI.0491.1246544	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133626	11.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/11/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0690	SKBTI.0491	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0491	M1-0690 biopsy	CCFA_RISK
SKBTI.0560.1247148	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133695	14.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	6/6/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0665	SKBTI.0560	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0560	M1-0665 biopsy	CCFA_RISK
MGH103891.1247371	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125755	44.0	no	11/21/63	human	0	9606	MiSeq	human gut metagenome	female	no	16	UBERON:colon	no	15.34	None	biopsy	7/1/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Current	PRISM	1939:7061	MGH103891	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	yes	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	yes	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Ascending colon	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH103891	7061 biopsy	CCFA_RISK
100101.1247239	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125854	58.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100101	100101	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100101	OR100101 stool	CCFA_RISK
SKBTI.0624.1246633	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133759	9.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	None	15.34	None	biopsy	7/8/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0639	SKBTI.0624	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0725	M1-0639 biopsy	CCFA_RISK
SKBTI.0510.1246292	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133645	15.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	None	15.34	None	biopsy	4/29/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0631	SKBTI.0510	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0510	M1-0631 biopsy	CCFA_RISK
SKBTI.0707.1246608	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135626	8.416666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	9/29/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0192	SKBTI.0707	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0707	M1-0192 biopsy	CCFA_RISK
SKBTI.1187.1246947	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162359	14.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	3/1/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0314	SKBTI.1187	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1187	M1-0314 biopsy	CCFA_RISK
121390.1247365	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136348	66.0	None	6/15/45	human	0	9606	MiSeq	human gut metagenome	female	yes	5	UBERON:feces	no	15.34	None	stool	5/22/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:7769	121390	408170	BI	.1,g	L4	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B2	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121390	7769 stool	CCFA_RISK
SKBTI.1281.1246303	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162456	6.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/14/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0458	SKBTI.1281	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1281	M1-0458 biopsy	CCFA_RISK
SKBTI.1147.1247101	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162436	12.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	8/15/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0788	SKBTI.1147	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1147	M1-0788 biopsy	CCFA_RISK
SKBTI.0751.1246389	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135665	15.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	11/3/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0263	SKBTI.0751	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0751	M1-0263 biopsy	CCFA_RISK
SKBTI.0222.1246765	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123078	9.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	3/3/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0384	SKBTI.0222	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0222	M1-0384 biopsy	CCFA_RISK
122057.1246165	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153064	21.0	None	8/2/91	human	0	9606	MiSeq	human gut metagenome	female	yes	1	UBERON:feces	yes	15.34	None	stool	1/2/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8649	122057	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122057	8649 stool	CCFA_RISK
SKBTI.0499.1247475	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133634	13.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/20/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0321	SKBTI.0499	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0499	M1-0321 biopsy	CCFA_RISK
MGH104031.1246987	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125783	40.0	yes	11/15/67	human	0	9606	MiSeq	human gut metagenome	female	no	13	UBERON:colon	no	15.34	None	biopsy	7/8/08	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7156	MGH104031	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH104031	7156 biopsy	CCFA_RISK
SKBTI.1077.1247114	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161043	11.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	11/16/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0555	SKBTI.1077	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1077	M1-0555 biopsy	CCFA_RISK
SKBTI.0271.1246207	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123126	12.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/4/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0592	SKBTI.0271	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0271	M1-0592 biopsy	CCFA_RISK
122004.1246853	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153074	30.0	None	12/1/82	human	0	9606	MiSeq	human gut metagenome	male	no	5	UBERON:feces	yes	15.34	None	stool	12/11/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8675	122004	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122004	8675 stool	CCFA_RISK
SKBTI.0871.1246124	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146975	13.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	12/23/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0607	SKBTI.0871	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0871	M1-0607 biopsy	CCFA_RISK
SKBTI.1151.1247347	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161075	11.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	8/8/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0615	SKBTI.1151	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1151	M1-0615 biopsy	CCFA_RISK
SKBTI.0262.1246726	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123117	15.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/21/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0319	SKBTI.0262	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0262	M1-0319 biopsy	CCFA_RISK
SKBTI.1008.1246146	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162420	15.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/15/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0306	SKBTI.1008	408170	BI	.1,g	L3	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.1008	M1-0306 biopsy	CCFA_RISK
SKBTI.1221.1246578	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161105	13.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:cecum	no	15.34	None	biopsy	8/25/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0761	SKBTI.1221	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1221	M1-0761 biopsy	CCFA_RISK
SKBTI.1303.1246234	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161189	10.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	None	15.34	None	biopsy	5/7/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0676	SKBTI.1303	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1303	M1-0676 biopsy	CCFA_RISK
121284.1246668	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136333	27.0	None	5/16/85	human	0	9606	MiSeq	human gut metagenome	male	no	6	UBERON:feces	no	15.34	None	stool	8/3/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8605	121284	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121284	8605 stool	CCFA_RISK
SKBTI091.1247314	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106962	16.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	12/6/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0649	SKBTI091	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI091	M1-0649 biopsy	CCFA_RISK
SKBTI.0594.1246183	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133729	10.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	None	15.34	None	biopsy	6/24/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0637	SKBTI.0594	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0594	M1-0637 biopsy	CCFA_RISK
SKBTI.1142.1246900	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161071	8.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	8/11/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0824	SKBTI.1142	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1142	M1-0824 biopsy	CCFA_RISK
SKBTI.0187.1246621	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123035	5.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/23/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0551	SKBTI.0187	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0187	M1-0551 biopsy	CCFA_RISK
SKBTI.0139.1247077	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122991	14.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	yes	15.34	None	biopsy	8/4/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	yes	other	BI	GAZ:United States of America	None	RISK	1939:M1-0366	SKBTI.0139	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0139	M1-0366 biopsy	CCFA_RISK
SKBTI.0742.1247322	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135656	7.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	2/8/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0412	SKBTI.0742	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0742	M1-0412 biopsy	CCFA_RISK
SKBTI.1079.1246482	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162308	15.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	11/19/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0723	SKBTI.1079	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1079	M1-0723 biopsy	CCFA_RISK
SKBTI.0654.1246889	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133789	8.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/27/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0624	SKBTI.0654	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0654	M1-0624 biopsy	CCFA_RISK
SKBTI078.1246624	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106949	15.0	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	None	15.34	None	biopsy	12/23/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0161	SKBTI078	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI078	M1-0161 biopsy	CCFA_RISK
SKBTI.0876.1246377	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146980	10.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	1/11/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0185	SKBTI.0876	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0876	M1-0185 biopsy	CCFA_RISK
SKBTI.1350.1246617	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161020	8.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	10/26/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0733	SKBTI.1350	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1350	M1-0733 biopsy	CCFA_RISK
SKBTI.0556.1247290	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133691	16.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/6/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0436	SKBTI.0556	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0556	M1-0436 biopsy	CCFA_RISK
122074.1246793	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153011	30.0	None	10/8/82	human	0	9606	MiSeq	human gut metagenome	female	no	1	UBERON:feces	no	15.34	None	stool	3/5/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8582	122074	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122074	8582 stool	CCFA_RISK
SKBTI.0281.1247228	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123135	14.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/12/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0457	SKBTI.0281	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0281	M1-0457 biopsy	CCFA_RISK
100211.1246832	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127133	74.0	yes	None	human	0	9606	MiSeq	human gut metagenome	female	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100211	100211	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100211	OR100211 stool	CCFA_RISK
SKBTI.0601.1247363	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133736	15.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/29/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0139	SKBTI.0601	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0601	M1-0139 biopsy	CCFA_RISK
SKBTI.0705.1246279	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155039	13.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	9/7/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0584	SKBTI.0705	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0705	M1-0584 biopsy	CCFA_RISK
SKBTI.0104.1246134	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122959	13.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/21/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0345	SKBTI.0104	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0104	M1-0345 biopsy	CCFA_RISK
SKBTI.1060.1246847	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162305	12.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	10/18/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0085	SKBTI.1060	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.1060	M1-0085 biopsy	CCFA_RISK
SKBTI.1222.1247133	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162376	9.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:cecum	no	15.34	None	biopsy	8/23/11	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0762	SKBTI.1222	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1222	M1-0762 biopsy	CCFA_RISK
SKBTI.1347.1246438	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162299	8.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:cecum	no	15.34	None	biopsy	10/21/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0835	SKBTI.1347	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1347	M1-0835 biopsy	CCFA_RISK
SKBTI.1254.1246881	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161169	5.083333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:cecum	no	15.34	None	biopsy	7/21/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0295	SKBTI.1254	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1254	M1-0295 biopsy	CCFA_RISK
SKBTI.0669.1246782	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133727	14.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	8/27/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0524	SKBTI.0669	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0669	M1-0524 biopsy	CCFA_RISK
121309.1246542	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136337	64.0	None	1/13/48	human	0	9606	MiSeq	human gut metagenome	male	no	30	UBERON:feces	no	15.34	None	stool	7/6/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:8505	121309	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121309	8505 stool	CCFA_RISK
SKBTI.0554.1247233	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133689	13.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/7/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0131	SKBTI.0554	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0554	M1-0131 biopsy	CCFA_RISK
SKBTI.0924.1246543	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147028	10.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	12/6/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0145	SKBTI.0924	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0924	M1-0145 biopsy	CCFA_RISK
SKBTI.1000.1246231	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161128	15.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	None	15.34	None	biopsy	3/2/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0775	SKBTI.1000	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1000	M1-0775 biopsy	CCFA_RISK
SKBTI.0230.1247214	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123085	14.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	4/6/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0415	SKBTI.0230	408170	BI	.1,g	L2	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0230	M1-0415 biopsy	CCFA_RISK
121307.1246550	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136335	25.0	None	3/7/87	human	0	9606	MiSeq	human gut metagenome	male	no	5	UBERON:feces	no	15.34	None	stool	7/5/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8466	121307	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121307	8466 stool	CCFA_RISK
SKBTI.1231.1246660	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162381	12.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	4/4/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0689	SKBTI.1231	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1231	M1-0689 biopsy	CCFA_RISK
SKBTI.1257.1247275	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162443	6.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/14/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0458	SKBTI.1257	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1257	M1-0458 biopsy	CCFA_RISK
SKBTI.1188.1246977	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161091	13.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	3/2/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0724	SKBTI.1188	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1188	M1-0724 biopsy	CCFA_RISK
MGH105700.1246519	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125764	34.0	no	6/17/74	human	0	9606	MiSeq	human gut metagenome	male	no	7	UBERON:ileum	no	15.34	None	biopsy	2/3/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7295	MGH105700	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	yes	CD	UBERON:gastrointestinal system	sequencing by synthesis	B3	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH105700	7295 biopsy	CCFA_RISK
SKBTI.1201.1246480	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162367	10.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	2/6/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0736	SKBTI.1201	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1201	M1-0736 biopsy	CCFA_RISK
SKBTI069.1246594	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106940	7.666666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/6/09	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0007	SKBTI069	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI069	M1-0007 biopsy	CCFA_RISK
100043.1246460	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125820	21.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100043	100043	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	100043	OR100043 stool	CCFA_RISK
SKBTI.0940.1246210	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147044	15.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	12/10/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0451	SKBTI.0940	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0940	M1-0451 biopsy	CCFA_RISK
SKBTI.0965.1247047	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161025	15.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:cecum	no	15.34	None	biopsy	2/24/10	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0227	SKBTI.0965	408170	BI	.1,g	L1	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0965	M1-0227 biopsy	CCFA_RISK
SKBTI.1009.1246428	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161132	11.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/29/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0417	SKBTI.1009	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1009	M1-0417 biopsy	CCFA_RISK
121387.1247113	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136345	60.0	None	2/4/52	human	0	9606	MiSeq	human gut metagenome	female	no	14	UBERON:feces	no	15.34	None	stool	9/25/12	0.0	None	ENVO:urban biome	None	Illumina	None	african	BI	GAZ:United States of America	Former	PRISM	1939:8095	121387	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121387	8095 stool	CCFA_RISK
SKBTI.1322.1247202	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162480	4.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/25/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0739	SKBTI.1322	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1322	M1-0739 biopsy	CCFA_RISK
SKBTI.0575.1246760	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133801	13.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	yes	15.34	None	biopsy	6/13/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0698	SKBTI.0575	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0575	M1-0698 biopsy	CCFA_RISK
121401.1247192	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136352	72.0	None	2/13/40	human	0	9606	MiSeq	human gut metagenome	female	no	1	UBERON:feces	no	15.34	None	stool	9/23/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8513	121401	408170	BI	.1,g	E1	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121401	8513 stool	CCFA_RISK
SKBTI.0592.1246198	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133706	15.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/28/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0559	SKBTI.0592	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0592	M1-0559 biopsy	CCFA_RISK
100109.1247329	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125860	48.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Current	OSCCAR	1939:OR100109	100109	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	100109	OR100109 stool	CCFA_RISK
121979.1246433	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153035	24.0	None	2/13/89	human	0	9606	MiSeq	human gut metagenome	female	no	1	UBERON:feces	no	15.34	None	stool	2/20/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8646	121979	408170	BI	.1,g	E1	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121979	8646 stool	CCFA_RISK
SKBTI.0136.1247052	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122988	13.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	9/28/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0038	SKBTI.0136	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0136	M1-0038 biopsy	CCFA_RISK
MGH104671.1247313	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136049	37.0	yes	7/8/71	human	0	9606	MiSeq	human gut metagenome	female	no	10	UBERON:colon	no	15.34	None	biopsy	8/10/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7124	MGH104671	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH104671	7124 biopsy	CCFA_RISK
SKBTI.0516.1247182	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133651	12.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	5/4/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0276	SKBTI.0516	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0516	M1-0276 biopsy	CCFA_RISK
MGH104316.1246666	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125763	51.0	yes	5/25/57	human	0	9606	MiSeq	human gut metagenome	male	no	9	UBERON:colon	no	15.34	None	biopsy	8/5/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7287	MGH104316	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Transverse colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH104316	7287 biopsy	CCFA_RISK
SKBTI.0198.1246368	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135988	16.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/7/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0305	SKBTI.0198	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0198	M1-0305 biopsy	CCFA_RISK
SKBTI.0203.1246320	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123142	2.333333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	None	15.34	None	biopsy	1/4/10	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0381	SKBTI.0203	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0203	M1-0381 biopsy	CCFA_RISK
SKBTI.0230.1247005	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155002	14.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	4/6/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0415	SKBTI.0230	408170	BI	.1,g	L2	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0230	M1-0415 biopsy	CCFA_RISK
SKBTI.0270.1247151	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123125	14.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/28/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0371	SKBTI.0270	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0270	M1-0371 biopsy	CCFA_RISK
MGH103128.1246694	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136055	39.0	no	11/15/68	human	0	9606	MiSeq	human gut metagenome	male	no	19	UBERON:ileum	no	15.34	None	biopsy	4/29/08	0.0	yes	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7056	MGH103128	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	yes	CD	UBERON:gastrointestinal system	sequencing by synthesis	B3	yes	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH103128	7056 biopsy	CCFA_RISK
SKBTI.1331.1246586	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161199	5.666666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	10/6/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0338	SKBTI.1331	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1331	M1-0338 biopsy	CCFA_RISK
SKBTI.1167.1246325	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161083	15.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	None	15.34	None	biopsy	7/28/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0405	SKBTI.1167	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1167	M1-0405 biopsy	CCFA_RISK
SKBTI.0961.1246630	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161023	12.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:cecum	no	15.34	None	biopsy	9/10/09	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0716	SKBTI.0961	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0961	M1-0716 biopsy	CCFA_RISK
SKBTI.0264.1246455	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155006	11.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/12/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0679	SKBTI.0264	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0264	M1-0679 biopsy	CCFA_RISK
SKBTI.0152.1246403	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123044	7.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	9/24/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0260	SKBTI.0152	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0152	M1-0260 biopsy	CCFA_RISK
122097.1247067	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153010	30.0	None	10/8/82	human	0	9606	MiSeq	human gut metagenome	female	no	1	UBERON:feces	no	15.34	None	stool	3/5/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8582	122097	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	122097	8582 stool	CCFA_RISK
SKBTI.0141.1246144	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122993	12.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	8/5/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0440	SKBTI.0141	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0141	M1-0440 biopsy	CCFA_RISK
SKBTI.0867.1247189	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-146971	11.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	1/7/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0567	SKBTI.0867	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0867	M1-0567 biopsy	CCFA_RISK
SKBTI.0145.1246298	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122997	16.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	8/16/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0255	SKBTI.0145	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0145	M1-0255 biopsy	CCFA_RISK
122034.1246771	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153076	21.0	None	2/14/91	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:feces	no	15.34	None	stool	1/14/13	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Current	PRISM	1939:8678	122034	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	122034	8678 stool	CCFA_RISK
SKBTI.0098.1246924	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135928	15.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	2/11/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0346	SKBTI.0098	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0098	M1-0346 biopsy	CCFA_RISK
SKBTI.0282.1246785	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123136	12.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/5/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0432	SKBTI.0282	408170	BI	.1,g	L2	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0282	M1-0432 biopsy	CCFA_RISK
SKBTI.0250.1246882	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123105	14.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	3/10/11	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0112	SKBTI.0250	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0250	M1-0112 biopsy	CCFA_RISK
SKBTI.1352.1246592	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162301	16.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	10/26/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0804	SKBTI.1352	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1352	M1-0804 biopsy	CCFA_RISK
SKBTI.0239.1246848	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123094	9.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/3/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0660	SKBTI.0239	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0239	M1-0660 biopsy	CCFA_RISK
SKBTI.1170.1246122	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162349	10.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:colon	no	15.34	None	biopsy	7/22/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0831	SKBTI.1170	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1170	M1-0831 biopsy	CCFA_RISK
SKBTI.0115.1246150	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122973	15.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	11/2/09	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0351	SKBTI.0115	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0115	M1-0351 biopsy	CCFA_RISK
SKBTI.0536.1246602	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133671	10.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	5/26/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0053	SKBTI.0536	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0536	M1-0053 biopsy	CCFA_RISK
SKBTI.1109.1247174	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162328	9.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	7/27/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0760	SKBTI.1109	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1109	M1-0760 biopsy	CCFA_RISK
SKBTI.1103.1247081	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161051	8.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	7/27/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0624	SKBTI.1103	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1103	M1-0624 biopsy	CCFA_RISK
SKBTI.0134.1247142	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122986	15.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	yes	15.34	None	biopsy	8/26/10	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0257	SKBTI.0134	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0134	M1-0257 biopsy	CCFA_RISK
SKBTI.0650.1246901	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133707	15.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	None	15.34	None	biopsy	7/28/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0405	SKBTI.0650	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0650	M1-0405 biopsy	CCFA_RISK
100092.1247222	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125849	62.0	yes	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100092	100092	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	100092	OR100092 stool	CCFA_RISK
SKBTI.1195.1247299	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161093	14.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	10/28/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0722	SKBTI.1195	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1195	M1-0722 biopsy	CCFA_RISK
SKBTI.0507.1246187	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133642	12.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/27/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0373	SKBTI.0507	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0507	M1-0373 biopsy	CCFA_RISK
SKBTI.0517.1247211	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133652	11.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	5/5/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0189	SKBTI.0517	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0517	M1-0189 biopsy	CCFA_RISK
SKBTI.0277.1247443	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136012	13.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/24/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0117	SKBTI.0277	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0277	M1-0117 biopsy	CCFA_RISK
SKBTI.0487.1247035	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133622	2.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/14/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0122	SKBTI.0487	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0487	M1-0122 biopsy	CCFA_RISK
SKBTI.1099.1247163	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161049	11.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	7/21/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0335	SKBTI.1099	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1099	M1-0335 biopsy	CCFA_RISK
SKBTI081.1246795	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106952	16.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	12/11/09	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0028	SKBTI081	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI081	M1-0028 biopsy	CCFA_RISK
SKBTI.0571.1246927	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133805	16.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	6/15/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0463	SKBTI.0571	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0571	M1-0463 biopsy	CCFA_RISK
SKBTI.0914.1246971	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29H3.1.Solexa-147018	16.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	yes	15.34	None	biopsy	8/4/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	east_asian	BI	GAZ:United States of America	None	RISK	1939:M1-0706	SKBTI.0914	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0914	M1-0706 biopsy	CCFA_RISK
122009.1246667	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29T3.1.Solexa-153072	31.0	None	6/12/81	human	0	9606	MiSeq	human gut metagenome	female	None	18	UBERON:feces	None	15.34	None	stool	11/14/12	0.0	None	ENVO:urban biome	None	Illumina	None	other	BI	GAZ:United States of America	Former	PRISM	1939:8658	122009	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	122009	8658 stool	CCFA_RISK
SKBTI.0198.1247382	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123055	16.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/7/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0305	SKBTI.0198	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0198	M1-0305 biopsy	CCFA_RISK
SKBTI.0156.1247394	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123007	16.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	10/19/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0501	SKBTI.0156	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0156	M1-0501 biopsy	CCFA_RISK
100016.1247155	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125819	46.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	None	0.0	yes	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	Never	OSCCAR	1939:OR100016	100016	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	None	IC	UBERON:feces	sequencing by synthesis	None	no	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	100016	OR100016 stool	CCFA_RISK
SKBTI.0632.1246416	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133767	11.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/8/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0309	SKBTI.0632	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0842	M1-0309 biopsy	CCFA_RISK
SKBTI.0238.1247283	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123093	12.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/2/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0316	SKBTI.0238	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0238	M1-0316 biopsy	CCFA_RISK
SKBTI.0118.1246522	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122972	11.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	yes	15.34	None	biopsy	11/19/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0487	SKBTI.0118	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0118	M1-0487 biopsy	CCFA_RISK
121193.1247063	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136310	48.0	None	1/25/64	human	0	9606	MiSeq	human gut metagenome	female	no	18	UBERON:feces	no	15.34	None	stool	4/17/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8494	121193	408170	BI	.1,g	E2	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121193	8494 stool	CCFA_RISK
SKBTI032.1247022	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106903	15.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	1/27/09	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0011	SKBTI032	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI032	M1-0011 biopsy	CCFA_RISK
SKBTI.0333.1247354	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-154980	15.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	11/10/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0598	SKBTI.0333	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0333	M1-0598 biopsy	CCFA_RISK
SKBTI.0572.1246658	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133804	13.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/14/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0545	SKBTI.0572	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0572	M1-0545 biopsy	CCFA_RISK
SKBTI.0227.1246253	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123082	None	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	None	15.34	None	biopsy	3/15/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0357	SKBTI.0227	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0227	M1-0357 biopsy	CCFA_RISK
SKBTI.0971.1246484	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161114	14.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:colon	no	15.34	None	biopsy	2/25/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0813	SKBTI.0971	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0971	M1-0813 biopsy	CCFA_RISK
MGH102797.1246385	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125769	41.0	no	7/28/66	human	0	9606	MiSeq	human gut metagenome	female	no	4	UBERON:ileum	no	15.34	None	biopsy	3/26/08	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7116	MGH102797	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B3	yes	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH102797	7116 biopsy	CCFA_RISK
SKBTI.0767.1246917	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135680	8.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	11/17/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0599	SKBTI.0767	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0767	M1-0599 biopsy	CCFA_RISK
SKBTI.0631.1247041	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133766	15.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/25/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0232	SKBTI.0631	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0631	M1-0232 biopsy	CCFA_RISK
121452.1247003	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136277	60.0	None	2/4/50	human	0	9606	MiSeq	human gut metagenome	female	no	19	UBERON:feces	yes	15.34	None	stool	6/8/10	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:7971	121452	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121452	7971 stool	CCFA_RISK
SKBTI.0186.1246672	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123034	14.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	7/14/10	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0249	SKBTI.0186	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0186	M1-0249 biopsy	CCFA_RISK
SKBTI.1298.1246756	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162465	14.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	9/6/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0818	SKBTI.1298	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1298	M1-0818 biopsy	CCFA_RISK
121496.1246759	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136416	67.0	None	3/12/45	human	0	9606	MiSeq	human gut metagenome	male	no	37	UBERON:feces	yes	15.34	None	stool	4/10/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Former	PRISM	1939:7238	121496	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121496	7238 stool	CCFA_RISK
SKBTI.0258.1247419	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123113	7.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/16/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0535	SKBTI.0258	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0258	M1-0535 biopsy	CCFA_RISK
SKBTI.1023.1246119	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161142	12.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	6/23/10	0.0	no	ENVO:urban biome	None	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0310	SKBTI.1023	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1023	M1-0310 biopsy	CCFA_RISK
SKBTI.1048.1246199	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161163	16.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:cecum	no	15.34	None	biopsy	9/17/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0833	SKBTI.1048	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1048	M1-0833 biopsy	CCFA_RISK
SKBTI.0181.1246719	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136075	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	7/2/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0245	SKBTI.0181	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0181	M1-0245 biopsy	CCFA_RISK
121467.1246327	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136291	54.0	None	4/13/55	human	0	9606	MiSeq	human gut metagenome	male	yes	28	UBERON:feces	no	15.34	None	stool	1/25/10	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:7853	121467	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B3	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121467	7853 stool	CCFA_RISK
121497.1246842	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136417	34.0	None	7/6/78	human	0	9606	MiSeq	human gut metagenome	female	no	13	UBERON:feces	no	15.34	None	stool	9/19/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Current	PRISM	1939:8622	121497	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B2	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121497	8622 stool	CCFA_RISK
MGH106034.1247069	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125780	25.0	yes	8/24/81	human	0	9606	MiSeq	human gut metagenome	male	no	10	UBERON:rectum	no	15.34	None	biopsy	2/6/07	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7145	MGH106034	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH106034	7145 biopsy	CCFA_RISK
SKBTI.0543.1246535	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133702	14.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/20/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0326	SKBTI.0543	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0543	M1-0326 biopsy	CCFA_RISK
121197.1247171	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136314	53.0	None	12/16/58	human	0	9606	MiSeq	human gut metagenome	male	no	31	UBERON:feces	no	15.34	None	stool	4/19/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8496	121197	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121197	8496 stool	CCFA_RISK
SKBTI.1211.1247024	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161099	16.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/6/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0699	SKBTI.1211	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1211	M1-0699 biopsy	CCFA_RISK
SKBTI092.1246887	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127153	7.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/29/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0300	SKBTI092	408170	BI	.1,g	L1	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI092	M1-0300 biopsy	CCFA_RISK
SKBTI.0161.1246229	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123045	11.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	4/29/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0517	SKBTI.0161	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0161	M1-0517 biopsy	CCFA_RISK
MGH105057.1246697	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125890	50.0	no	7/28/58	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:colon	None	15.34	None	biopsy	10/22/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7356	MGH105057	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	MGH105057	7356 biopsy	CCFA_RISK
SKBTI.0163.1247195	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123013	9.083333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/10/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0418	SKBTI.0163	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0163	M1-0418 biopsy	CCFA_RISK
SKBTI.0157.1246907	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123008	15.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/15/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0306	SKBTI.0157	408170	BI	.1,g	L3	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.0157	M1-0306 biopsy	CCFA_RISK
MGH101003.1247243	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125788	30.0	no	3/6/77	human	0	9606	MiSeq	human gut metagenome	male	no	12	UBERON:colon	no	15.34	None	biopsy	9/18/07	0.0	yes	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7228	MGH101003	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	yes	UC	UBERON:gastrointestinal system	sequencing by synthesis	None	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Descending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	MGH101003	7228 biopsy	CCFA_RISK
SKBTI.0259.1247216	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123114	11.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	None	15.34	None	biopsy	3/16/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0661	SKBTI.0259	408170	BI	.1,g	L3	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0259	M1-0661 biopsy	CCFA_RISK
MGH101748.1247032	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125750	50.0	yes	12/16/57	human	0	9606	MiSeq	human gut metagenome	female	no	10	UBERON:colon	no	15.34	None	biopsy	12/18/07	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	Never	PRISM	1939:7039	MGH101748	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Ascending colon	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH101748	7039 biopsy	CCFA_RISK
SKBTI.1173.1247321	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161086	13.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:rectum	no	15.34	None	biopsy	7/25/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0781	SKBTI.1173	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1173	M1-0781 biopsy	CCFA_RISK
SKBTI.0142.1247126	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-122994	11.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	8/6/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0480	SKBTI.0142	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0142	M1-0480 biopsy	CCFA_RISK
SKBTI.1135.1246413	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162338	14.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	8/9/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0795	SKBTI.1135	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1135	M1-0795 biopsy	CCFA_RISK
SKBTI.1249.1246317	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162440	10.91666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	4/3/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0808	SKBTI.1249	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1249	M1-0808 biopsy	CCFA_RISK
MGH103539.1246371	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125781	45.0	yes	3/15/63	human	0	9606	MiSeq	human gut metagenome	male	no	23	UBERON:colon	no	15.34	None	biopsy	6/10/08	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7153	MGH103539	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Sigmoid	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH103539	7153 biopsy	CCFA_RISK
SKBTI.0287.1247430	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136005	12.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	1/13/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0103	SKBTI.0287	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0287	M1-0103 biopsy	CCFA_RISK
SKBTI013.1246574	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106884	13.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/1/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0059	SKBTI013	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI013	M1-0059 biopsy	CCFA_RISK
SKBTI.0226.1247286	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123081	9.833333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	3/15/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0413	SKBTI.0226	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0226	M1-0413 biopsy	CCFA_RISK
120157.1246601	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136295	23.0	None	8/16/86	human	0	9606	MiSeq	human gut metagenome	male	None	None	UBERON:feces	None	15.34	None	stool	3/22/10	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	None	PRISM	1939:7906	120157	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	None	no	UBERON:feces	sequencing by synthesis	None	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	121178	7906 stool	CCFA_RISK
SKBTI027.1247232	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106898	14.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/6/10	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0173	SKBTI027	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI027	M1-0173 biopsy	CCFA_RISK
SKBTI.1287.1246942	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162458	13.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	8/25/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0843	SKBTI.1287	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1287	M1-0843 biopsy	CCFA_RISK
SKBTI.1213.1247264	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162373	5.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	2/15/12	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0805	SKBTI.1213	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1213	M1-0805 biopsy	CCFA_RISK
SKBTI.0508.1246383	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133643	15.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	4/29/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0125	SKBTI.0508	408170	BI	.1,g	L3	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0508	M1-0125 biopsy	CCFA_RISK
SKBTI.0713.1246511	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135631	7.333333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	8/25/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0288	SKBTI.0713	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0713	M1-0288 biopsy	CCFA_RISK
SKBTI.0267.1246891	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123122	13.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	3/23/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0318	SKBTI.0267	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0267	M1-0318 biopsy	CCFA_RISK
SKBTI.0641.1247015	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155017	3.583333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	6/16/11	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0464	SKBTI.0641	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0641	M1-0464 biopsy	CCFA_RISK
SKBTI.0672.1246688	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135618	10.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	2/14/12	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0056	SKBTI.0672	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0672	M1-0056 biopsy	CCFA_RISK
SKBTI.1125.1247091	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162334	14.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	8/5/11	0.0	no	ENVO:urban biome	None	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0406	SKBTI.1125	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1125	M1-0406 biopsy	CCFA_RISK
SKBTI.0682.1246734	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A29AM.1.Solexa-135694	9.416666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	5/16/12	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0711	SKBTI.0682	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0682	M1-0711 biopsy	CCFA_RISK
SKBTI.0618.1247191	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133753	12.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	7/7/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0546	SKBTI.0618	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0618	M1-0546 biopsy	CCFA_RISK
SKBTI.1288.1247416	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162459	14.16666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	8/29/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0728	SKBTI.1288	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1288	M1-0728 biopsy	CCFA_RISK
SKBTI.1172.1247248	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162350	12.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	7/25/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0842	SKBTI.1172	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1172	M1-0842 biopsy	CCFA_RISK
SKBTI063.1247098	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106934	13.58333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	5/6/09	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0022	SKBTI063	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI063	M1-0022 biopsy	CCFA_RISK
SKBTI.0189.1246454	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123037	14.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/24/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0495	SKBTI.0189	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0189	M1-0495 biopsy	CCFA_RISK
SKBTI.0237.1246742	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123092	15.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	3/1/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0315	SKBTI.0237	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0237	M1-0315 biopsy	CCFA_RISK
SKBTI.1062.1246758	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161029	14.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:cecum	no	15.34	None	biopsy	10/15/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0814	SKBTI.1062	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1062	M1-0814 biopsy	CCFA_RISK
SKBTI.0233.1246991	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123088	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	2/25/11	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	other	BI	GAZ:United States of America	None	RISK	1939:M1-0580	SKBTI.0233	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0233	M1-0580 biopsy	CCFA_RISK
MGH106271.1246160	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136033	57.0	yes	6/27/51	human	0	9606	MiSeq	human gut metagenome	male	no	19	UBERON:rectum	no	15.34	None	biopsy	4/7/09	0.0	yes	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Former	PRISM	1939:7242	MGH106271	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH106271	7242 biopsy	CCFA_RISK
SKBTI.0112.1246189	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135937	14.41666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	1/29/10	0.0	no	ENVO:urban biome	inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0491	SKBTI.0112	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0112	M1-0491 biopsy	CCFA_RISK
SKBTI.1038.1246448	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162427	16.5	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	9/3/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0720	SKBTI.1038	408170	BI	.1,g	None	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.1038	M1-0720 biopsy	CCFA_RISK
SKBTI.0275.1247370	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-136016	14.66666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	3/31/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	african	BI	GAZ:United States of America	None	RISK	1939:M1-0627	SKBTI.0275	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0275	M1-0627 biopsy	CCFA_RISK
SKBTI.0609.1246252	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133744	10.75	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	7/4/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0702	SKBTI.0609	408170	BI	.1,g	L1	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0609	M1-0702 biopsy	CCFA_RISK
SKBTI.0567.1247219	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133639	15.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	6/13/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0329	SKBTI.0567	408170	BI	.1,g	L1	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0567	M1-0329 biopsy	CCFA_RISK
SKBTI.0647.1247016	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133782	10.83333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	yes	15.34	None	biopsy	7/26/11	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0285	SKBTI.0647	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0647	M1-0285 biopsy	CCFA_RISK
SKBTI.1353.1247119	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162302	16.33333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:rectum	no	15.34	None	biopsy	10/26/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0804	SKBTI.1353	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.1353	M1-0804 biopsy	CCFA_RISK
121402.1247186	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136353	24.0	None	8/5/88	human	0	9606	MiSeq	human gut metagenome	male	no	10	UBERON:feces	no	15.34	None	stool	10/1/12	0.0	None	ENVO:urban biome	None	Illumina	None	other	BI	GAZ:United States of America	Never	PRISM	1939:8377	121402	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B2	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121402	8377 stool	CCFA_RISK
SKBTI.1196.1247407	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A4848.1.Solexa-162364	11.0	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	2/1/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0735	SKBTI.1196	408170	BI	.1,g	None	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.1196	M1-0735 biopsy	CCFA_RISK
SKBTI.0136.1246640	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135943	13.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	9/28/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	None	RISK	1939:M1-0038	SKBTI.0136	408170	BI	.1,g	L2	years	1939	UC	study of normal and IBD samples	no	UC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	SKBTI.0136	M1-0038 biopsy	CCFA_RISK
SKBTI.0211.1247078	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2F7T.1.Solexa-135991	15.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	no	15.34	None	biopsy	2/1/10	0.0	no	ENVO:urban biome	None	Illumina	no	other	BI	GAZ:United States of America	None	RISK	1939:M1-0301	SKBTI.0211	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0211	M1-0301 biopsy	CCFA_RISK
121215.1247158	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136322	63.0	None	7/23/48	human	0	9606	MiSeq	human gut metagenome	female	no	11	UBERON:feces	no	15.34	None	stool	6/11/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8515	121215	408170	BI	.1,g	E3	years	1939	UC	study of normal and IBD samples	None	UC	UBERON:feces	sequencing by synthesis	no	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	UC	42.358	121215	8515 stool	CCFA_RISK
SKBTI.0218.1246657	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP7.1.Solexa-123074	13.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	2/24/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0226	SKBTI.0218	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0218	M1-0226 biopsy	CCFA_RISK
MGH101446.1246835	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2246.1.Solexa-125771	53.0	no	2/18/54	human	0	9606	MiSeq	human gut metagenome	male	no	5	UBERON:rectum	no	15.34	None	biopsy	10/31/07	0.0	no	ENVO:urban biome	non-inflamed	Illumina	no	None	BI	GAZ:United States of America	Current	PRISM	1939:7123	MGH101446	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B2	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	MGH101446	7123 biopsy	CCFA_RISK
SKBTI.1326.1247062	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161198	9.083333333	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:rectum	no	15.34	None	biopsy	9/2/09	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0741	SKBTI.1326	408170	BI	.1,g	L3	years	1939	IC	study of normal and IBD samples	no	IC	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	IC	42.358	SKBTI.1326	M1-0741 biopsy	CCFA_RISK
121423.1246854	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2NWB.1.Solexa-136360	70.0	None	5/6/42	human	0	9606	MiSeq	human gut metagenome	male	no	57	UBERON:feces	no	15.34	None	stool	10/21/12	0.0	None	ENVO:urban biome	None	Illumina	None	caucasian	BI	GAZ:United States of America	Never	PRISM	1939:8579	121423	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	None	CD	UBERON:feces	sequencing by synthesis	B1	None	-71.06	ENVO:feces	16S rRNA	None	ENVO:human-associated habitat	None	stool	UBERON:feces	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	121423	8579 stool	CCFA_RISK
SKBTI.0254.1246289	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2RAA.1.Solexa-155004	16.25	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:ileum	no	15.34	None	biopsy	3/15/11	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0114	SKBTI.0254	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI.0254	M1-0114 biopsy	CCFA_RISK
SKBTI.0518.1246864	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A1UEN.1.Solexa-133653	13.75	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:ileum	yes	15.34	None	biopsy	3/1/11	0.0	no	ENVO:urban biome	inflamed	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0506	SKBTI.0518	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.0518	M1-0506 biopsy	CCFA_RISK
SKBTI.1317.1247132	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161192	9.416666667	no	None	human	0	9606	MiSeq	human gut metagenome	male	no	0	UBERON:rectum	no	15.34	None	biopsy	4/30/12	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0810	SKBTI.1317	408170	BI	.1,g	None	years	1939	CD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Rectum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1317	M1-0810 biopsy	CCFA_RISK
SKBTI024.1246988	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2WP4.1.Solexa-106895	16.25	no	None	human	0	9606	MiSeq	human gut metagenome	female	yes	0	UBERON:ileum	no	15.34	None	biopsy	3/25/10	0.0	no	ENVO:urban biome	non-inflamed	Illumina	yes	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0072	SKBTI024	408170	BI	.1,g	L2	years	1939	cCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	non-inflamed	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	no	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI024	M1-0072 biopsy	CCFA_RISK
SKBTI.1035.1246669	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A2G81.1.Solexa-161153	11.08333333	no	None	human	0	9606	MiSeq	human gut metagenome	male	yes	0	UBERON:cecum	no	15.34	None	biopsy	11/16/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0821	SKBTI.1035	408170	BI	.1,g	L3	years	1939	iCD	study of normal and IBD samples	no	CD	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Cecum	UBERON:mucosa	yes	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	CD	42.358	SKBTI.1035	M1-0821 biopsy	CCFA_RISK
SKBTI089.1247376	None	GTGCCAGCMGCCGCGGTAA	V4	n	BI	CCFA_RISK	A222Y.1.Solexa-127151	5.916666667	no	None	human	0	9606	MiSeq	human gut metagenome	female	no	0	UBERON:ileum	no	15.34	None	biopsy	9/16/10	0.0	no	ENVO:urban biome	None	Illumina	no	caucasian	BI	GAZ:United States of America	None	RISK	1939:M1-0588	SKBTI089	408170	BI	.1,g	None	years	1939	no	study of normal and IBD samples	no	no	UBERON:gastrointestinal system	sequencing by synthesis	B1	no	-71.06	ENVO:organic material	16S rRNA	None	ENVO:human-associated habitat	None	Terminal ileum	UBERON:mucosa	None	None	BI	FWD:GTGCCAGCMGCCGCGGTAA; REV:GGACTACHVGGGTWTCTAAT	This analysis was done as in Caporaso et al 2011 Genome research. The PCR primers (F515/R806) were developed against the V4 region of the 16S rRNA (both bacteria and archaea), which we determined would yield optimal community clustering with reads of this length using a procedure similar to that of ref. 15. [For reference, this primer pair amplifies the region 533_786 in the Escherichia coli strain 83972 sequence (greengenes accession no. prokMSA_id:470367).] The reverse PCR primer is barcoded with a 12-base error-correcting Golay code to facilitate multiplexing of up to ?_1,500 samples per lane, and both PCR primers contain sequencer adapter regions.	no	42.358	SKBTI089	M1-0588 biopsy	CCFA_RISK